Latest news with #Danos
Yahoo
21-05-2025
- Business
- Yahoo
Coave Therapeutics Establishes New Scientific Advisory Board to Accelerate Innovation in Genetic Medicines for Eye and CNS Diseases
Paris, France – May 21, 2025 – Coave Therapeutics ('Coave'), a company pioneering the future of genetic medicines, today announces the evolution of its Scientific Advisory Board (SAB). This renewed SAB reflects Coave's strategic shift from a platform-focused approach to the development of a therapeutic pipeline, as the Company advances multiple gene therapy programs. The SAB brings together internationally recognized leaders in adeno-associated viral (AAV) vector biology, gene therapy development for ophthalmology and central nervous system (CNS) diseases, and innovative approaches to extra-hepatic gene delivery. The SAB members include: Olivier Danos, PhD (Chair) – Chief Scientific Officer at REGENXBIO (Rockville, MD, USA) Dr. Danos is a pioneer in gene therapy with over 30 years of academic and industrial leadership, including roles at Biogen, Genethon and University College London, and now leads REGENXBIO's scientific strategy Robin Ali, PhD – Professor of Human Molecular Genetics at King's College London (London, UK) and Founder of MeiraGTx Dr. Ali is a world-leading expert in gene therapy for retinal diseases and a pioneer of translational research advancing vision restoration therapies Aravind Asokan, PhD – Professor at Duke University School of Medicine and Director of the Danaher Beacon for Gene Therapy Innovation (Durham, NC, USA) Dr. Asokan specializes in AAV vector biology and synthetic virology, developing engineered AAVs to enable next-generation gene therapies Juliette Hordeaux, DVM, PhD – Chief Scientific Officer at GEMMA Biotherapeutics (Philadelphia, PA, USA) and formerly Executive Director of Translational Research at the Gene Therapy Program, University of Pennsylvania (Philadelphia, PA, USA) Dr. Hordeaux is a recognized leader in the development of AAV-based CNS-targeted gene therapies, focused on translating preclinical innovations to clinical-stage programs Federico Mingozzi, PhD – Chief Executive Officer of Nava Therapeutics (Philadelphia, PA, USA) Dr. Mingozzi brings extensive expertise in gene therapy R&D and translation, having previously served as Chief Scientific Officer at Spark Therapeutics and earlier led programs at Genethon, INSERM and the Children's Hospital of Philadelphia Amy Pooler, PhD – Senior Vice President, Research and Development at Life Edit Therapeutics (Durham, NC, USA), previously Vice President, Head of Research at Sangamo Therapeutics (Brisbane, CA, USA) Dr. Pooler has extensive experience in translational neuroscience and genetic medicine, with leadership roles in developing CNS-targeted therapies at Sangamo and Life Edit The SAB members will provide strategic scientific and clinical guidance to support Coave's R&D initiatives, leveraging its ALIGATER™ (Advanced Vectors-Ligand Conjugates) platform to unlock improved precision and safety in genetic medicine. Their combined expertise strengthens Coave's leadership in developing AAV-based therapeutics targeting diseases beyond the liver, including the eye and CNS. Lolita Petit, CSO of Coave Therapeutics commented, 'We are absolutely delighted to welcome this exceptional group of world-leading experts to our Scientific Advisory Board. Their collective expertise across AAV biology, gene therapy development and translational research will be invaluable as we continue to enhance our ALIGATER™ platform and advance our therapeutic pipeline. Their support reinforces our commitment to delivering next-generation genetic medicines with improved precision and safety and accelerates our mission to transform the lives of patients with serious unmet medical needs.' *** Photos of SAB members available on request About ALIGATER™Coave's proprietary ALIGATER™ (Advanced Vectors-Ligand Conjugates) platform is a breakthrough technology addressing key limitations in the delivery of genetic payloads to extra-hepatic tissues, including limited tissue specificity, delivery efficiency and safety. ALIGATER™ enables conjugation of targeting ligands, such as small molecules, peptides, or antibody fragments, on AAV or non-viral vectors, offering superior delivery efficiency, tissue specificity and safety profile for a broad range of diseases. Importantly, the platform streamlines the manufacturing process by avoiding prior AAV capsid modifications. These capabilities will enable Coave to develop best-in-class gene therapies designed for specific indications. About Coave Therapeutics Coave Therapeutics is a genetic medicine company pioneering the development of innovative solutions to enhance the precision, safety, efficacy and manufacturability of genetic medicines. With its proprietary ALIGATER™ platform, Coave is at the forefront of addressing challenges in gene therapy delivery to extra-hepatic tissues, creating a robust pipeline targeting CNS, neuromuscular and eye diseases. Headquartered in Paris, France, Coave Therapeutics is backed by leading international life sciences investors. For more information about the science, pipeline, and people, please visit and follow us on LinkedIn. CONTACTS Coave Therapeutics Rodolphe Clerval, CEO contact@ MEDiSTRAVA Sylvie Berrebi, Mark Swallow coavetx@ in to access your portfolio
Yahoo
14-05-2025
- Health
- Yahoo
Likely ‘rabid' fox bites hiker 6 times in rare attack
SAN MARCOS, Texas (KXAN) – Michelle Danos, a Texas State University student, said she went to a lower Purgatory Creek trail Sunday evening to clear her head. 'I got off work, thought maybe I want to go on a hike,' she said. Fox reportedly attacks at least four in San Marcos, prompting rabies concerns She walked toward a field of blooming Prairie coneflowers when she heard rustling behind her. 'It was a fox,' Danos said. 'It just started walking towards me.' While it wasn't foaming at the mouth or charging at her, Danos said she knew something was off as it began approaching her. Foxes generally are elusive and keep to themselves. 'It got behind me and ended up biting my ankle,' she said. Danos tried running away, hitting it with rocks, and physically throwing the fox, but it kept returning to attack her. She finally escaped after throwing the fox into a cactus. She got bitten six times and lost her cellphone in the attack. 'I've had a lot of [rabies] shots,' she said. 'I have to get more tomorrow, and then seven days, and then 14 days. So it's a process.' The fox, which officials are pretty sure was rabid, bit several people on Sunday. Natasia Moore, an urban biologist with the Texas Parks and Wildlife Department, said fox attacks in Texas are exceedingly rare. 'It's not typical behavior,' Moore said. 'This [is] the first case of a fox attack in Texas that I know of to date.' Moore went with crews on Monday to the Purgatory Creek Natural Area to investigate the incident. Officials were interested in finding out if there was denning activity in the area, which could have been a cause for the aggression. 'In urban areas, if an animal is showing aggression, it can be because they are protecting a den site,' Moore said. 'We did not see any fox activity.' 'Unfortunately, [a rabies infection] is looking like the most likely scenario,' Moore continued. ' Raccoon in San Marcos tests positive for rabies, residents urged to vaccinate pets According to the Centers for Disease Control and Prevention, rabies is 'a fatal but preventable viral disease' that can spread between people and animals through bites and scratches. The disease can cause severe brain disease and death if not treated before symptoms start. As of Tuesday evening, the fox had not been located. Officials told Nexstar's KXAN that if it has rabies, it likely will die soon, if not already dead. Pet owners should vaccinate their pets against rabies, which is essential in preventing the spread of the virus and is required by state law, the city said. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Yahoo
14-05-2025
- Yahoo
‘Rabid' fox bites hiker six times in rare fox attack
SAN MARCOS, Texas (KXAN) – Michelle Danos, a Texas State University student, said she went to a lower Purgatory Creek trail Sunday evening to clear her head. 'I got off work, thought maybe I want to go on a hike,' she said. Fox reportedly attacks at least four in San Marcos, prompting rabies concerns She walked toward a field of blooming Prairie coneflowers when she heard rustling behind her. 'It was a fox,' Danos said. 'It just started walking towards me.' While it wasn't foaming at the mouth or charging at her, Danos said she knew something was off as it began approaching her. Foxes generally are elusive and keep to themselves. 'It got behind me and ended up biting my ankle,' she said. Danos tried running away, hitting it with rocks, and physically throwing the fox, but it kept returning to attack her. She finally escaped after throwing the fox into a cactus. She got bitten six times and lost her cellphone in the attack. 'I've had a lot of [rabies] shots,' she said. 'I have to get more tomorrow, and then seven days, and then 14 days. So it's a process.' The fox, which officials are pretty sure was rabid, bit several people on Sunday. Natasia Moore, an urban biologist with the Texas Parks and Wildlife Department, said fox attacks in Texas are exceedingly rare. 'It's not typical behavior,' Moore said. 'This [is] the first case of a fox attack in Texas that I know of to date.' Moore went with crews on Monday to the Purgatory Creek Natural Area to investigate the incident. Officials were interested in finding out if there was denning activity in the area, which could have been a cause of the aggression. 'In urban areas, if an animal is showing aggression, it can be because they are protecting a den site,' Moore said. 'We did not see any fox activity.' 'Unfortunately, [a rabies infection] is looking like the most likely scenario,' Moore continued. As of Tuesday evening, the fox has still not been located. Pet owners should vaccinate their pets against rabies, which is essential in preventing the spread of the virus and is required by state law, the city said. People can find out more about obtaining vaccinations by visiting this link. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
Yahoo
19-02-2025
- Business
- Yahoo
Danos Foundation awards $438,100 in grants to 22 nonprofits
Feb. 19—GRAY, La. — The Danos Foundation has awarded $438,100 in grants to 22 nonprofit organizations across South Louisiana, Mississippi, Texas and Montana. The Foundation received over 100 applications and selected recipients based on their impact and alignment with its purpose. Funds awarded through Danos GIVES, the Foundation's grant-giving program, support organizations that strengthen families, create sustainable solutions and make a lasting impact in communities where Danos employees live and work. "The Danos Foundation embodies our belief that God created all people in His image, and we have a responsibility to care for and serve others," said Mark Danos, CEO of Danos Family Investments. "Through Danos GIVES, we invest in organizations that directly impact the communities our colleagues call home." Texas grant recipients include eight nonprofit organizations: Hope's Path, $50,000; Permian Basin Mission Center, $30,000; Skillpoint Alliance, $30,000; Family Promise of Odessa, Inc., $25,000; Houston Furniture Bank, $20,000; Bynum School, $10,000; Basin Dream Center, $10,000; Bill's Backpacks, $4,000. Danos employees established the Danos Foundation in 2017 to fulfill the company's purpose: "Honor God. Develop great people to solve big challenges for our customers and communities." Funded by employee contributions and supplemented by Danos, the Foundation extends its impact beyond Danos GIVES through Danos WORKS, which provides funding to organizations where employees volunteer. This initiative further strengthens the communities where Danos employees live and work. As Danos Group has expanded, so has the reach of the Danos Foundation, now supporting employees' communities through Performance Energy Services and Danos Operations Services. For a complete list of GIVES recipients, visit To apply for a 2025 grant, visit
