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Time of India
3 days ago
- Health
- Time of India
Hair Regrowth Without Transplant? New Molecular Approach Offers Hope
Mumbai: A team of scientists by mapping the complete molecular network of human hair, have identified several treatment procedures that can potentially eliminate the need for surgery or transplants for restoring hair growth. According to a recent study published in "Stem Cell Research & Therapy" integrating stem cell biology, gene therapy, and molecular signalling can potentially help to treat hair loss conditions like androgenetic alopecia (AGA) without the need of a transplant. The study co-authored by a multidisciplinary team from US and India, involving researchers of QR678, a hair regrowth formulation and The Esthetic Clinics (TEC) , suggest androgenetic alopecia (AGA)—the most common form of hair loss—not as an irreversible condition, but as a breakdown in regenerative signalling that can potentially be reversed.' Under the study, the researchers analysed five key molecular pathways—Wnt/β-catenin, Sonic Hedgehog (Shh), Bone Morphogenetic Protein (BMP), Notch, and AKT/MAPK—that collectively manage the hair follicle lifecycle. During their analysis, researchers found that in conditions like AGA, the communication between these aforementioned pathways breaks down, particularly with Wnt suppression and BMP overactivation, causing follicles to fall into dormancy. To correct such breakdowns the study outlined that gene-editing tools like CRISPR and stem cell therapies can help to correct misfiring signals, rebuild a supportive microenvironment. As per the researchers some of these treatments have already shown success in lab-grown tissue and animal models, and early clinical trials are expected to begin within the next two years. 'By mapping out the molecular misfires behind hair follicle dormancy, we now have a clearer pathway to develop therapies that don't just slow hair loss—but potentially reverse it by reawakening the body's own regenerative systems,' said Dr Michael Gold, dermatologist and founder of Gold Skin Care Center, USA. 'Hair follicles don't disappear; they go dormant due to disrupted cellular signals. By identifying how these signals fail—and how they can be restored—we move closer to resetting the system at a molecular level. It's a fundamental shift in how hair loss can be understood, and ultimately, reversed,' Dr Debraj Shome, senior author and Director at TEC, added. Scientists involved in the study suggest the global hair loss treatment market, valued around $4 billion (₹34,000 crore) available solutions includes only external therapies–-drugs, and treatment procedures—surgery, transplants. Whereas, the study's findings signal a space for exploring gene- and cell-based molecular therapies—a therapeutic domain that follows a completely different approach with differentiated targeting and treatment mechanisms.

Associated Press
07-06-2025
- Health
- Associated Press
Dr. Michael H. Gold Inducted into The International Order of Fantastic Professionals
'Dr. Michael Gold's depth of expertise and extraordinary commitment to global education and innovation are unparalleled.'— Dr. Allen Lycka EDMONTON, ALBERTA, CANADA, June 7, 2025 / / -- The International Order of Fantastic Professionals is proud to announce that Dr. Michael H. Gold, a board-certified dermatologist, internationally recognized researcher, and founder of multiple leading dermatologic institutions, has been officially inducted into the IOFP and awarded the Global Leader in Dermatologic Advancement 2025. IOFP celebrates Dr. Gold's distinguished career, spanning over three decades. His groundbreaking contributions to dermatologic science, cosmetic medicine, and global education have elevated the field of aesthetic dermatology worldwide. Since founding Gold Skin Care Center and its affiliated organizations in Nashville, Tennessee, in 1990, Dr. Gold has overseen the development and implementation of cutting-edge technologies and procedures in dermatologic and aesthetic medicine. Through the Tennessee Clinical Research Center, he has led pivotal FDA Phase II-IV trials, directly influencing the future of dermatologic treatments and product innovation. Beyond his clinical work, Dr. Gold is a committed educator and author, having written over 500 scientific articles, contributed to 40 textbook chapters, and served as editor-in-chief for multiple international dermatology journals. He is also the co-founder of SCALE, DASIL, and the 5-Continent Congress conferences, which have become pillars in the global dermatology and aesthetics communities. ' Dr. Michael Gold's depth of expertise and extraordinary commitment to global education and innovation are unparalleled,' said Dr. Allen Lycka, founder and CEO of the International Order of Fantastic Professionals. 'We look forward to watching the continued change his leadership inspires in others around the world.' About the International Order of Fantastic Professionals (IOFP): The International Order of Fantastic Professionals (IOFP) is a prestigious global community of forward-thinking leaders committed to innovation, collaboration, and making a meaningful difference. Representing a diverse range of industries, IOFP members are recognized for their excellence and for delivering innovative solutions to today's most pressing challenges. Learn more at For media inquiries and more information on IOFP initiatives, contact: Tami McCalla, Director of Operations Email: [email protected] Dr. Allen Lycka Dr. Allen Lycka Prof Corp email us here Legal Disclaimer: EIN Presswire provides this news content 'as is' without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.