
Hair Regrowth Without Transplant? New Molecular Approach Offers Hope
According to a recent study published in "Stem Cell Research & Therapy" integrating stem cell biology, gene therapy, and
molecular signalling
can potentially help to treat hair loss conditions like
androgenetic alopecia
(AGA) without the need of a transplant.
The study co-authored by a multidisciplinary team from US and India, involving researchers of QR678, a
hair regrowth
formulation and The Esthetic Clinics (TEC)
, suggest
androgenetic alopecia (AGA)—the most common form of hair loss—not as an irreversible condition, but as a breakdown in regenerative signalling that can potentially be reversed.'
Under the study, the researchers analysed five key molecular pathways—Wnt/β-catenin, Sonic Hedgehog (Shh), Bone Morphogenetic Protein (BMP), Notch, and AKT/MAPK—that collectively manage the hair follicle lifecycle.
During their analysis, researchers found that in conditions like AGA, the communication between these aforementioned pathways breaks down, particularly with Wnt suppression and BMP overactivation, causing follicles to fall into dormancy.
To correct such breakdowns the study outlined that gene-editing tools like CRISPR and stem cell therapies can help to correct misfiring signals, rebuild a supportive microenvironment.
As per the researchers some of these treatments have already shown success in lab-grown tissue and animal models, and early clinical trials are expected to begin within the next two years.
'By mapping out the molecular misfires behind hair follicle dormancy, we now have a clearer pathway to develop therapies that don't just slow hair loss—but potentially reverse it by reawakening the body's own regenerative systems,' said Dr Michael Gold, dermatologist and founder of Gold Skin Care Center, USA.
'Hair follicles don't disappear; they go dormant due to disrupted cellular signals. By identifying how these signals fail—and how they can be restored—we move closer to resetting the system at a molecular level. It's a fundamental shift in how hair loss can be understood, and ultimately, reversed,' Dr Debraj Shome, senior author and Director at TEC, added.
Scientists involved in the study suggest the global hair loss treatment market, valued around $4 billion (₹34,000 crore) available solutions includes only external therapies–-drugs, and treatment procedures—surgery, transplants.
Whereas, the study's findings signal a space for exploring gene- and cell-based molecular therapies—a therapeutic domain that follows a completely different approach with differentiated targeting and treatment mechanisms.
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Hindustan Times
11 hours ago
- Hindustan Times
World Lipstick Day: Dermatologist reveals if using lipstick every day safe for your lips
Let's admit it ladies, we all have tons of lipstick shades in our drawer and we of course don't mind adding a few more! Be it a ravishing and bold red lip shade for a night out or a nude shade for all your work days, we have different shades for different occasion. However, frequent and unmindful usage of lipsticks can lead to skin concerns, says a dermatologist on the occasion of World Lipstick Day. World Lipstick Day: Dr. Rinky Kapoor tells how safe are lipstick(Pexels) 'Lips are uniquely vulnerable because they lack oil glands and have thinner skin, making them prone to dryness, irritation, and pigmentation. Prolonged use of low-quality lipsticks, particularly those containing synthetic dyes, preservatives, or fragrances, can contribute to issues like allergic contact cheilitis or chronic chapping, especially if the product isn't removed thoroughly at the end of the day,' dermatologist Dr Rinky Kapoor, Director and Co-Founder of The Esthetic Clinics, tells HT Lifestyle. This is why it is crucial to pick your lipstick wisely and refrain from any low-quality lipsticks. She suggests on choosing high quality lipsticks, preferably, apply with SPF infused lip balm to protect them from the UV rays. Are lipsticks safe to use daily? Most dermatologically-tested lipsticks are safe for daily wear. According to Dr Kapoor, these days, many modern formulas include hydrating agents like vitamin E, squalene, or natural oils that are safe to use. However, repeated application, especially without a hydrating base, can cause dryness or irritation in some users. She also claims that a few lipsticks may also have low levels of heavy metals like lead or cadmium in certain products, which is unsafe for your lips in the long run. 'That's why I advise using lipsticks from transparent, well-regulated brands and paying attention to how your lips respond," says Dr Kapoor. Are natural or organic lipsticks better for lips? 'Not always,' says the expert. 'The terms 'natural' and 'organic' are appealing, but they don't guarantee safety. While organic lipsticks may avoid synthetic dyes and preservatives, they are not immune to causing irritation. The real benefit lies in simpler ingredient lists and fewer additives, which can help those with sensitivities," she adds. In a nutshell, the safest lipstick, as per her is not the most botanical, it's the one that's well-tested, well-formulated, and suited to your individual skin type. How to maintain lip care while using lipstick regularly? Avoid over-applying drying, matte formulas, and always remove lipstick completely at the end of the day. 'Healthy lips require more than just choosing the right lipstick, it begins with a protective base, a hydrating, non-irritating balm, to reduce moisture loss and irritation,' she asserts. In addition, Dr Kapoor also recommends gentle exfoliation that helps prevent flaking and improves product application. She also suggests using an overnight lip mask or thick balm to support skin repair. 'Also consider SPF-infused lip products to prevent sun-induced pigmentation, which is often overlooked', says Dr. Rinky. What to look for in a dermatologically safe lipstick? 'Look for lipsticks labelled hypoallergenic, fragrance-free, and dermatologically tested. These markers indicate lower risk of irritation," explains Dr Kapoor. Also look for hydrating ingredients like shea butter, jojoba oil, ceramides, or vitamin E in your lipstick. 'Avoid vague terms like parfum, harsh preservatives, and overly bright synthetic dyes unless they are certified for cosmetic use." And when in doubt, patch test! Understanding ingredient labels: Spotting irritants and allergens Reading ingredient labels can feel daunting, but a few common red flags make it easier. 'Irritants often include synthetic dyes like Red 7 Lake, parabens, artificial fragrances, and preservatives like methylisothiazolinone," she says. The fact is that even natural ingredients like peppermint oil, lanolin, or citrus extracts can trigger reactions in sensitive users. Dr Kapoor recommends to look for full INCI (International Nomenclature of Cosmetic Ingredients) listings and certifications like ECOCERT or EWG Verified. Rise of conscious beauty: How consumers can make safer choices The conscious beauty movement has shifted focus from appearance to overall wellness and ingredient integrity. This is especially important for products like lipstick, where ingestion of trace ingredients is a possibility. Today's consumers are more informed and demand transparency, which is a welcome change. 'To make safer choices, read labels, know your sensitivities, and opt for brands that provide full ingredient disclosures and undergo clinical testing. Ethical production and environmental responsibility are added benefits—but they must go hand in hand with dermatological safety. Informed beauty is beautiful, and far safer in the long run,' she says. Though, these above-mentioned points will help you find the perfect lipstick without damaging your lips in the long run, it is crucial to consult a dermatologist or skin expert if you have persistent skin issues or are allergic to any ingredient. In a nutshell, applying lipsticks is fine and healthy unless you are using a high quality product, and keep your lips nourished to prevent dryness. Similar articles for you: Hair care routine for women: Our ultimate guide for silky, shiny, and glossy hair How AI is revolutionising skincare by offering personalised and precise skin remedies: Experts say it's here to stay Celebrity makeup artist Namrata Soni suggests top makeup tips to ace your monsoon look How to clean your makeup brush and sponges for the ultimate hygiene check; Our detailed guide for you Disclaimer: At Hindustan Times, we help you stay up-to-date with the latest trends and products. Hindustan Times has an affiliate partnership, so we may get a part of the revenue when you make a purchase. We shall not be liable for any claim under applicable laws, including but not limited to the Consumer Protection Act, 2019, with respect to the products. The products listed in this article are in no particular order of priority.


News18
a day ago
- News18
National Lipstick Day 2025: Must-Try Lipstick Trends and Shades For The Season
Last Updated: In 2025, lipstick is evolving, but its power remains timeless. Clean, conscious, and crafted for real lives, today's lipsticks go beyond pigment 'Lipstick has always been more than a beauty staple; it's a marker of moments. It's the first swipe before a big meeting, the shade you reached for the night everything changed, or the colour that made you feel most like yourself, even on an ordinary day.' In 2025, lipstick is evolving, but its power remains timeless. Clean, conscious, and crafted for real lives, today's lipsticks go beyond pigment. They reflect mood, mindset, and meaning. On National Lipstick Day, we're reminded that something as small as a lipstick can still carry the weight of transformation, the thrill of confidence, and the quiet power of self-expression all in one effortless gesture. Dr. Rinky Kapoor, Director and Co-Founder of The Esthetic Clinics (TEC), explains, 'For many, applying lipstick is a daily ritual, a boost of confidence, an expression of identity or a signature look. But when used every day—especially products that contain synthetic dyes, parabens, or heavy metals—we do start to see long-term effects; things like persistent dryness, allergic reactions, or even lip pigmentation. Matte and long-wear lipsticks, while trendy, are particularly drying and can contribute to darkening if you are not protecting or hydrating your lips enough." She adds, 'What most people don't realise is that the skin on our lips is different. It has no oil glands, making it more vulnerable to chapping and irritation. At TEC®, we treat many patients for lip pigmentation, inflammation, or even contact dermatitis, often triggered by overuse of harsh cosmetic products. Treatments like low-energy lasers, mild peels, and prescription balms can help—but prevention is always better." Her tips? 'Choose lipsticks that are dermatologically tested, never skip a nourishing balm with SPF, avoid licking your lips, and exfoliate gently once a week." Now that we're ready to celebrate with care, here's a curated edit of must-try lipsticks and balms making waves this season: Anastasia Beverly Hills Lip Velvet Anastasia Beverly Hills Lip Velvet, a luxurious velvet-smooth lip mousse that provides a weightless, true-matte finish. With its full-pigment color and soft-focus effect, it beautifully enhances her lips. The teardrop-shaped cushioned wand ensures easy application, making it perfect for any festive look. Available in nine versatile shades, this gift is ideal for adding a touch of elegance and vibrancy to her celebrations under the moonlight! 13 Shades Available – Parchment, Peach Amber, Crush, Pure Hollywood, Peachy Nude, Kiss, Rosy Mauve, Softy, Pale Mauve, Hush Rose, Pomegranate, Cool Brown, Blackberry This National Lipstick Day, say it without saying a word with ColorBar's Sinful Liquid Lipstick. A bold expression of modern glamour, this ultra-luxurious, powder-matte formula is designed for those who believe their lip colour should speak volumes. The mousse-like texture glides on effortlessly, delivering full-bodied pigment in a single, cloud-soft stroke. Infused with advanced transfer-proof and smudge-resistant formulation, it stays flawless through every hour, every mood, and every moment, without drying, feathering, or fading. Available in 12 versatile shades, from barely-there nudes to bold, high-drama tones, each hue is thoughtfully crafted to complement a wide range of skin tones and styles. Whether you're leaning soft or statement-making, this is a colour that moves with you. Price: INR 1,499 Modicare's Urban Color London Matte Vogue Luxe Slim Lipstick Make a statement worthy of the crown with Modicare's Urban Color London's Matte Vogue Luxe Slim Lipstick, brought to you by Modicare. This lipstick delivers bold, defined lips with 8 striking shades that offer long-lasting, full-coverage matte color. Enriched with Avocado Oil, Vitamin E, Vitamin D, and Beta Carotene, it nourishes and protects your lips while providing a smooth, dramatic finish. Priced at MRP ₹999 (incl. of all taxes), this vegan and paraben-free lipstick is the perfect blend of care and intensity for your royal look. Price: INR 999 Oriflame's The ONE Ultimate Glitter Lipstick Oriflame's The ONE Ultimate Glitter Lipstick transforms your lips with a luxurious gemstone-inspired design that sparkles with every smile. This silky-smooth, creamy formula glides effortlessly while delivering a stunning luminous finish that catches the light beautifully. The buildable coverage lets you create anything from subtle shimmer to bold, dramatic statements perfect for any occasion. Experience the magic of precious gem beauty with this enchanting blend of colours and mesmerizing glitter, available in shades of Red Gem, Unique Nude and Wow-factor Pink, that makes your lips shine like the finest jewels. Price: INR 1,399 Love Season Velvety Bullet Lipstick | 12 Hour Stay – Sunlit Charm Trio This National Lipstick Day, let your lips do the talking with Color Cupid's velvety bullet lipstick trio, a celebration of color, confidence, and charm. The Love Season collection glides on like a dream, delivering bold pigment in a single swipe while keeping your lips soft and hydrated all day. With 12-hour stay power and shades that suit every mood and moment, the Sunlit Charm Trio is your go-to for timeless glam. Because nothing says self-love like a lipstick that loves you back. Price: INR 897 Kay Beauty Matte Drama Long Stay Lipstick – Dream Girl Every girl needs a trusty matte lipstick, one that doesn't smudge, budge or nudge from her lips. The Kay Beauty Matte Drama Lipstick is here to give you luxurious matte lips and unleash the power of long stay. Its velvety luxe texture is what makes it the most coveted of all matte lipsticks, and spells pure opulence. Just one stroke is all it takes to cover your lips with high-impact colour. The iconic weightless formula feels feathery light on the lips and is comfortable for all-day wear. With grapeseed oil and red raspberry in its care ingredients, the formula also moisturizes while protecting your lips from sun damage and blue light. Available in 24 flattering shades, it's designed to suit every Indian skin tone. Price: INR 849 Max Factor Colour Elixir Liquid Lipstick Max Factor Colour Elixir Soft Matte Lip Colour! The ultra weightless and lightweight texture provides a bare lip sensation and beautiful powder matte finish for soft blurred lips. Formulated with lightweight waxes and oils, the lip colour leaves a moisturised feeling whilst the ultra fine pigments flex with your lips and blur any imperfections. Availability – Nykaa, Myntra, Amazon, Tata Cliq, Health & Glow, Dabur NewU and Shoppers Stop Price – INR 900 Avon Ultra Perfectly Matte Lipstick This Lipstick Day, get ready to own every pout with Avon's Ultra Perfectly Matte Lipstick where comfort meets colour like never before! Designed for every skin tone, this high-impact, velvety matte formula delivers intense payoff in one swipe without the dryness. The secret? A new oil-infused blend that hydrates while giving you bold, confident colour. The signature teardrop bullet ensures precise, effortless application even on the go. Plus, it's cruelty-free. Say hello to soft, smooth and statement lips and a matte finish that moves with you. Price: INR 529 KIKO Milano's Unlimited Double Touch Liquid Lipstick This Lipstick Day, let your lips shine with KIKO Milano's Unlimited Double Touch Liquid Lipstick, a long-lasting dual formula that delivers rich pigment and glass-like radiance. The base colour glides on smoothly, offering intense coverage and comfort with a quick-dry, smudge-resistant finish. Top it off with the high-shine gloss for 12 hours of luminous wear and soft, kiss-ready lips. Because bold lips deserve beauty that lasts. Price: INR 1,390 House of Makeup: Dab n Glow Easy-Blend Lip & Cheek Tint If you love the barely-there flush of a good tint, this one's a must. Feather-light, beautifully buildable, and blendable with just your fingertips, this creamy tint gives your lips that popsicle-stained vibe while doubling up as a cheek colour. The formula melts in, leaves a soft, dewy finish. Beauty by BiE: Indulgent LipCare Rituals- Nourishing Lip Balms Elevate your lip care game with Beauty by BiE's indulgent Balms, Berry Pop and Coffee and Creme. These rich, nourishing formulas are crafted with skin-loving ingredients that hydrate, smooth, and revive. Packed with the goodness of jojoba oil, vitamin E, and squalane, this lip balm for dry and chapped lips transforms your pout with a luxurious blend of natural moisturizers. Whether you're prepping for a bold lip or craving an overnight moisture fix, this pocket-sized luxury delivers visible softness in every swipe. The sensorial notes of strawberries or coffee add to a deeply nourishing ritual. A modern beauty essential for lips that feel as good as they look, minimal effort, maximum payoff. Pepti Matte SPF Mousse Lipstick Pepti Matte SPF Mousse Lipstick's lightweight, long-lasting mousse texture offers smudge-proof wear and broad-spectrum SPF protection-like a loving shield that keeps your lips safe and radiant through every moment shared. Price: 1299/- Intuition Lipstick A full-coverage, creamy, skin-hugging lipstick that moves with you. Intuition Cream Lipstick glides and delivers the rich color payoff of a true lipstick without dryness, heaviness, or doubt. top videos View all Designed for everyday moods and in-between moments, it gives your lips a smooth, velvety finish that feels nourishing and looks effortless. Price: 849/- About the Author Swati Chaturvedi Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she's a weaver of wit and wisdom in the digital landscape. As a key figure in News18 More The News18 Lifestyle section brings you the latest on health, fashion, travel, food, and culture — with wellness tips, celebrity style, travel inspiration, and recipes. Also Download the News18 App to stay updated! view comments Location : New Delhi, India, India First Published: July 28, 2025, 13:03 IST News lifestyle National Lipstick Day 2025: Must-Try Lipstick Trends and Shades For The Season Disclaimer: Comments reflect users' views, not News18's. Please keep discussions respectful and constructive. Abusive, defamatory, or illegal comments will be removed. News18 may disable any comment at its discretion. By posting, you agree to our Terms of Use and Privacy Policy.


Time of India
2 days ago
- Time of India
Health dept distances itself from rape accused
Gaya: The health department has clarified that the ambulance driver and technician accused of raping a home guard job aspirant in Gaya are not its regular employees but were hired through a private agency. The alleged incident took place on July 24 when the woman was raped inside a slow-moving ambulance between the Bihar Military Police (BMP) ground and Anugrah Narayan Magadh Medical College Hospital. Speaking to reporters, Gaya civil surgeon Dr Raja Ram Prasad said, "Both the driver and the technician are not regular employees of the health department. Their recruitment was done by a private agency engaged at the state level. Therefore, the question of departmental action against them does not arise." When asked whether background checks had been conducted before the duo were deployed, the civil surgeon said, "It is for the agency to explain." On the medical report of the survivor, Bodh Gaya SDPO Saurav Jaiswal said it was expected to be made available soon. "The sealed report will be received by the investigating officer, Rinku Kumari," he said. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like No annual fees for life UnionBank Credit Card Apply Now Undo Gaya SSP Anand Kumar said the survivor's statement would be recorded before a judicial magistrate. "The statement will be taken under Section 183 of the Bharatiya Nagarik Suraksha Sanhita (BNSS), which is the amended version of Section 164 of the CrPC," he said. Meanwhile, questions have been raised over possible administrative lapses at the recruitment venue. Authorities have yet to clarify whether a doctor was present at the site or who authorised the woman's hospitalisation without standard precautions, such as ensuring a woman attendant accompanied her.