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Business Standard
22-05-2025
- Health
- Business Standard
Working 52+ hours a week may physically change your brain, warns new study
If you've ever bragged about 'killing it' at work by clocking long hours week after week, this might be your wake-up call. A new study titled 'Overwork and changes in brain structure: a pilot study', published in the journal Occupational & Environmental Medicine (a BMJ publication), has found that working 52 hours or more per week may actually be altering your brain, particularly the regions responsible for memory, problem-solving, and emotional regulation. Conducted by a team of South Korean researchers from Yonsei University, Chung-Ang University, and Pusan National University, the study used advanced brain imaging techniques to examine 110 healthcare workers. They found that overworked individuals showed notable structural changes in their brains, changes that could help explain the emotional and cognitive struggles often reported by people who work excessively long hours. How does working long hours affect brain structure? The researchers compared healthcare workers who routinely worked 52 hours or more a week to those who worked fewer hours. Using Magnetic Resonance Imaging (MRI)-based techniques, voxel-based morphometry (VBM) and atlas-based volume analysis, they found that overworked individuals had significantly increased brain volume in areas associated with executive function (like decision-making and working memory) and emotional regulation. One of the most affected regions was the left middle frontal gyrus, along with the insula and superior frontal gyrus, parts of the brain linked to emotional balance and problem-solving. While these changes might sound like brain 'growth,' they are more likely neuroadaptive responses to chronic stress and fatigue. What did the study reveal about the brain and overwork? Here are the key findings: The left caudal middle frontal gyrus showed a 19 per cent increase in volume in the overworked group. Significant volume increases were also seen in 17 other brain regions, including those tied to executive and emotional functions. These changes correlated positively with the number of hours worked each week. Even after adjusting for confounding lifestyle factors like smoking and exercise, many associations held strong. Notably, while increased grey matter is often interpreted as a sign of learning or positive adaptation, researchers caution that in the context of overwork, it may reflect compensatory or even maladaptive responses to chronic stress and lack of rest. While we already know overwork is tied to mental health issues like depression and anxiety, this research goes deeper to understand the physical and structural changes in the brain that may underlie these problems. Previous studies mostly focused on psychological and behavioural outcomes. This study adds a new layer of evidence by connecting those outcomes with biological changes in brain anatomy. Which brain functions are impacted by structural changes? The affected brain regions help regulate how we make decisions, solve problems, and manage emotions. Alterations in these areas could contribute to: Reduced cognitive efficiency Difficulty in focusing or problem-solving Emotional instability Higher susceptibility to burnout, anxiety, and depression And the consequences might not just be short-term. Over time, these changes could impact long-term brain health, including risks for cognitive decline. What workplace changes does the study recommend? The study's authors call for immediate action from employers and policymakers, especially in high-demand professions like healthcare. They emphasise, 'Our findings underscore the importance of addressing overwork as an occupational health concern and highlight the need for workplace policies that mitigate excessive working hours.' Given that the International Labour Organization (ILO) already estimates 800,000 deaths annually from overwork, the study lends urgent neurobiological weight to a public health issue that's been brewing for decades. What can employees and employers do to protect brain health? While this is a pilot study and further research is needed, it does tell us that brain health should be a priority in the conversation about work-life balance. Here are some actionable takeaways: Employers should design better shift schedules, encourage breaks, and cap weekly hours to reduce mental load. Workers should monitor their mental and emotional states, prioritise rest and recovery, and seek help when signs of burnout appear. Policymakers should set stricter guidelines around maximum work hours and implement regulations to protect employee well-being. Long hours may seem necessary sometimes, but your brain might be paying the price in ways you cannot see. The next time you're tempted to push through yet another late night at work, just remember: boundaries and balance are important for your brain health. For more health updates, follow #HealthWithBS
India Today
05-05-2025
- Health
- India Today
India gets first-of-its-kind tech that tracks cancer tumours in real-time
India received its first Elekta Unity MR Linac, an advanced cancer treatment system that combines real-time Magnetic Resonance Imaging (MRI) with precise radiation machine, currently being installed at Yashoda Medicity in Ghaziabad, is also the country's first to include Comprehensive Motion Management (CMM), a feature that improves accuracy by tracking even the slightest body movement during simple terms, this system combines two important features: an MRI scanner (hich shows clear pictures of the inside of the body) and a radiation machine (which targets and kills cancer cells).advertisement The machine tracks tiny movements in the body while treating cancer. That means if a patient moves or breathes, the machine adjusts in real time so the radiation still hits exactly the right allows doctors to adapt radiation doses on a daily basis, based on changes in a patient's anatomy. The result is better targeting of cancer cells while protecting nearby it uses MRI instead of regular CT scans, it gives much clearer images, especially of soft tissues like can change the treatment plan every day based on how the patient's body is responding. The Elekta Unity system tracks tiny movements in the body while treating cancer. (Photo: Yashoda Medicity) advertisementThis makes the treatment more accurate, safer, and faster, especially helpful for people with small tumours or those who need radiation more than Elekta Unity system uses a high-resolution 1.5 Tesla MRI scanner to provide clear, real-time images of tumours and surrounding healthy is especially useful for treating small tumours, lymph nodes, and cases where patients need to undergo radiation more than machine also supports hypo-fractionated treatment, delivering higher doses in fewer sessions, making the process quicker and more comfortable for patients."This is a transformative step in cancer care. We can now personalise each radiation session in real time, improving outcomes and reducing side effects," said Dr Upasana Arora, Managing Director of Yashoda new system also enables remote treatment planning. Doctors can review and approve patient plans from anywhere, improving speed and also sets the stage for future approaches like Biology-Guided Radiotherapy (BgRT), which aims to personalise treatment based on biological signals such as gene Gagan Saini, Vice Chairman and Head of Radiation & Oncology at Yashoda Medicity, said the technology is a timely addition, given that over 1.4 million new cancer cases are reported in India every MR Linac ensures faster, safer, and more precise treatment, especially for patients requiring repeat therapy," he operational, the Elekta Unity MR Linac is expected to set a new benchmark for cancer care in India.
Yahoo
06-03-2025
- Business
- Yahoo
Molecular Spectroscopy Market Size Booms with CAGR 4.9% and Projected to Reach $5.6 Million by 2030
NEW YORK, March 6, 2025 /PRNewswire/ -- According to a comprehensive report from The Insight Partners, "Molecular Spectroscopy Market share and Forecasts 2022 - 2030, Global and Regional Share, Trend, and Growth Opportunity Analysis By Product (Instrument and Accessories), Technology (UV-Visible Spectroscopy, Infrared Spectroscopy, Nuclear Magnetic Resonance Spectroscopy, Raman Spectroscopy, Near-Infrared Spectroscopy, and Others), Application (Academic and Research Applications, Biotechnology Applications, Pharmaceutical Applications, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)", The global molecular spectroscopy market is expected to reach US$ 5.6 Million by 2030 from US$ 3.8 Million in 2022; it is estimated to record a CAGR of 4.9% during the forecast period To explore the valuable insights in the Molecular Spectroscopy Market report, you can easily download a sample PDF of the report- The Molecular Spectroscopy Market Report provides valuable insights that help market players identify emerging trends, opportunities, and competitive dynamics. It offers data on market size, growth forecasts, and regional demand, allowing companies to plan effectively. The report also highlights technological advancements, regulatory landscapes, and consumer behavior, enabling players to stay ahead of the curve. By understanding these factors, businesses can make informed decisions on product development, investments, and market strategies, ultimately gaining a competitive edge and driving growth in the market. Competitive Strategy and Development Key Players: Major companies operating in the molecular spectroscopy market are Thermo Fisher Scientific, Inc, Merck KGaA, PerkinElmer Inc., Agilent Technologies, Inc, Bruker, Horiba, Ltd, Shimadzu Corporation, JEOL Ltd, and JASCO, among others. Trending Topics: Process Spectroscopy Market, Computational molecular spectroscopy, UV-visible spectroscopy, Infrared Spectroscopy, Nuclear Magnetic Resonance Spectroscopy, Raman Spectroscopy, Near-Infrared Spectroscopy, Mass spectrometry (MS), etc. Global Headlines on the Molecular Spectroscopy Market Metrohm Expands Raman Portfolio MJH Life Sciences Spectroscopy Announces the Acquisition of Spectroscopy Europe and Spectroscopy World For Detailed Molecular Spectroscopy Market Insights, Visit: Molecular Spectroscopy Market Overview of Report Findings Market Growth: The global molecular spectroscopy market is expected to reach US$ 5.6 Million by 2030 from US$ 3.8 Million in 2022; it is estimated to record a CAGR of 4.9% during the forecast period. Due to technological advancements, increased need for pharmaceutical research and development, stringent environmental monitoring regulations, and food safety standards, the market for molecular spectroscopy is growing significantly. UV-visible, infrared, and NMR spectroscopy are molecular spectroscopy methods commonly used in the biotech and pharmaceutical sectors for qualitative and quantitative analysis, ensuring quality control and compliance. The market is expected to expand gradually over the next several years due to innovation being driven by industry giants like Agilent Technologies and Thermo Fisher Scientific. Pharmaceutical and Biotech Industry Growth: Rigid medication safety laws implemented by agencies such as the FDA and EMA have also forced pharmaceutical companies to employ spectroscopic methods to ensure compliance requirements. Also, the higher incidence of chronic diseases has increased the need for new medicine forms, placing a greater focus on molecular spectroscopy. Since the biotech and pharma industries expand globally, most prominently in developing economies, molecular spectroscopy is expected to be used more and more. Due to this, it is imperative for quality assurance, innovation, and precision in medicine. Raman spectroscopy is used to identify compounds, study molecular structure, and the quality and safety of drugs. Due to these technologies, which are not to be parted with for investigating biomolecules, impurity detection, and reaction monitoring, improved and more effective treatments are formulated. Besides, the need for molecular spectroscopy for protein characterization, stability studies, and process monitoring has increased due to the growth in biologics and biosimilars. Technological Advancements: Miniature spectrometers, sophisticated data analysis software, and Al and machine learning integration are some of the most important developments that have simplified molecular spectroscopy technologies and made them usable in various industries. For instance, with portable and handheld spectrometers, on-site testing is realized in environmental monitoring and food safety. Large-scale molecular analysis is possible owing to the improvements in Raman and Fourier-transform infrared (FTIR) spectroscopy, with increased sensitivity and resolution. These advances are most valuable to pharmaceutical R&D, where accurate characterization of molecules is necessary for drug development. In addition, processes have been streamlined, and real-time monitoring has been enabled by interfacing spectroscopy systems with automation and cloud-based systems. With such advancements evolving, they are expanding the scope of applications of molecular spectroscopy, pushing its application in scientific review and industrial uses. Geographic Insights: In 2023, North America led the market with a substantial revenue share, followed by Europe and Asia Pacific. Further, Asia Pacific is expected to record the highest CAGR during the forecast period. Stay Updated on The Latest Molecular Spectroscopy Market Trends: Market Segmentation Based on product, the molecular spectroscopy market is segmented into instrument and accessories. The instrument segment held a larger share of the market in 2022. In terms of technology, the molecular spectroscopy market is segmented into UV-visible spectroscopy, infrared spectroscopy, nuclear magnetic resonance spectroscopy, Raman spectroscopy, near-infrared spectroscopy, and others. The infrared spectroscopy segment dominated the market in 2022. On the basis of application, the molecular spectroscopy market is segmented into academic and research applications, biotechnology applications, pharmaceutical applications, and others. The pharmaceutical applications segment dominated the market in 2022. The molecular spectroscopy market is segmented into five major regions: North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. Purchase Premium Copy of Global Molecular Spectroscopy Market Size and Growth Report (2023-2031) at: Conclusion The molecular spectroscopy market is growing because it is pivotal in many industries, such as pharma, biotech, and research. Molecular spectroscopic methods such as UV-visible, IR, Raman, NMR, and Near-Infrared (NIR) spectroscopy are used widely for qualitative and quantitative analysis of molecules, enabling precise identification, characterization, and monitoring of compounds. Moreover, the technological innovations that have resulted in the miniaturization of devices and increased resolution, along with integration with Al and machine learning, are expanding the scope of spectroscopy applications. Emerging economies also drive market growth through industrialization and research facility investment. Key players such as Thermo Fisher Scientific, Agilent Technologies, and Bruker Corporation are at the forefront of innovation and product development to meet evolving industry demands. With accuracy, compliance with regulations, and as technology innovation becomes imperative for industries, the market for molecular spectroscopy is predicted to grow incrementally, holding tremendous scope for research and industrial innovations. The report from The Insight Partners provides several stakeholders—including manufacturers, sales manager, and end users—with valuable insights into how to successfully navigate this evolving market landscape and unlock new opportunities. Related Reports- Spectroscopy IR Detector Market Size and Forecasts (2021 - 2031), Global and Regional Share, Trends, and Growth Opportunity Analysis Near Infrared Spectroscopy Market Size and Forecasts (2021 - 2031), Global and Regional Share, Trends, and Growth Opportunity Analysis Raman Spectroscopy Market Dynamics, Analysis, Growth, and Trends by 2031 Other related Life Sciences Market Research Reports - About Us: The Insight Partners is a one stop industry research provider of actionable intelligence. We help our clients in getting solutions to their research requirements through our syndicated and consulting research services. We specialize in industries such as Semiconductor and Electronics, Aerospace and Defense, Automotive and Transportation, Biotechnology, Healthcare IT, Manufacturing and Construction, Medical Device, Technology, Media and Telecommunications, Chemicals and Materials. Contact Us: If you have any queries about this report or if you would like further information, please contact us: Contact Person: Ankit MathurE-mail: +1-646-491-9876Press Release- Logo: View original content: SOURCE The Insight Partners
Miami Herald
05-02-2025
- Miami Herald
Inside Diddy's late-night trip to the hospital under ‘the cover of darkness'
Sean 'Diddy' Combs was briefly sprung from prison late Thursday night. The disgraced rapper, who has been behind bars at Metropolitan Detention Center in Brooklyn since September, was apparently dealing with a medical issue, The New York Post reports. The 55 year old was transported to a nearby hospital 'under cover of darkness' to have an MRI (Magnetic Resonance Imaging) of his knee. A source told the newspaper that Combs had been dealing with some pain and that he's had knee issues since running the New York Marathon more than 20 years ago. According to CBS News, the music mogul developed 'severe tendinitis' in his right knee while training for the grueling 26.2 mile race in 2003. 'Never in my life have I ever experienced anything as crazy as this,' said the hip-hop entrepreneur after crossing the finish line. 'It was a beautiful experience.' After Thursday night's scan, Combs was reportedly taken back to his cell. It's unclear if surgery or any other treatment is required as MDC does not comment on inmate matters. The 'Hello Good Morning' singer, who still maintains a home on Star Island in Miami Beach, was indicted on sex trafficking charges last year after a federal investigation; his trial is set for May.
Associated Press
30-01-2025
- Business
- Associated Press
Aclarion Announces Pricing of Registered Direct Offering of Common Stock Priced at the Market
NEWMEDIAWIRE) - Aclarion, Inc., ('Aclarion' or the 'Company') (Nasdaq: ACON, ACONW), a healthcare technology company that is leveraging biomarkers and proprietary augmented intelligence (AI) algorithms to help physicians identify the location of chronic low back pain, today announced that it has agreed to sell 506,803 shares of its common stock at a price per share of $9.25 in a registered direct offering priced at the market. All of the shares of common stock in the offering are being sold by Aclarion. The closing of the offering is expected to take place on or about January 31, 2025, subject to the satisfaction of customary closing conditions. The gross proceeds to Aclarion from this offering are expected to be approximately $4.7 million, before deducting the placement agent's fees and other offering expenses payable by Aclarion. Aclarion intends to use the net proceeds from the offering to fund market development and clinical evidence, product development and quality, and general and administration support, and other general corporate purposes. Dawson James Securities, Inc. is acting as the sole placement agent for the offering. The offering is being made pursuant to a shelf registration statement on Form S-3 (File No. 333-281999) that was declared effective by the Securities and Exchange Commission ('SEC') on September 23, 2024. The offering may be made only by means of a prospectus supplement and accompanying prospectus. A final prospectus supplement with the final terms of the offering will be filed with the SEC and will be available for free on the SEC's website, located at Copies of the prospectus supplement and the accompanying prospectus relating to the offering may be obtained, when available, from Dawson James Securities, Inc., 101 North Federal Highway, Suite 600, Boca Raton, FL 33432 or by telephone at (561) 391-5555, or by email at [email protected]. This press release does not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of that state or jurisdiction. About Aclarion, Inc. Aclarion is a healthcare technology company that leverages Magnetic Resonance Spectroscopy ('MRS'), proprietary signal processing techniques, biomarkers, and augmented intelligence algorithms to optimize clinical treatments. The Company is first addressing the chronic low back pain market with Nociscan, the first, evidence-supported, SaaS platform to noninvasively help physicians distinguish between painful and nonpainful discs in the lumbar spine. Through a cloud connection, Nociscan receives magnetic resonance spectroscopy (MRS) data from an MRI machine for each lumbar disc being evaluated. In the cloud, proprietary signal processing techniques extract and quantify chemical biomarkers demonstrated to be associated with disc pain. Biomarker data is entered into proprietary algorithms to indicate if a disc may be a source of pain. When used with other diagnostic tools, Nociscan provides critical insights into the location of a patient's low back pain, giving physicians clarity to optimize treatment strategies. Caution Regarding Forward-Looking Statements This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Words such as 'may,' 'might,' 'will,' 'should,' 'believe,' 'expect,' 'anticipate,' 'estimate,' 'continue,' 'predict,' 'forecast,' 'project,' 'plan,' 'intend' or similar expressions, or statements regarding intent, belief, or current expectations are forward-looking statements and reflect the current beliefs of Aclarion's management. Such forward-looking statements include, without limitation, statements relating to the completion of the offering and the intended use of proceeds. These statements are not guarantees of future performance and are subject to certain risks, uncertainties and other factors that could cause actual results and events to differ materially and adversely from those indicated by such forward-looking statements including, among others: risks and uncertainties related to market conditions and the satisfaction of customary closing conditions related to the offering, and other risks and uncertainties related to the offering, as well as the risks and uncertainties set forth in the 'Risk Factors' section and elsewhere in the prospectus supplement related to the offering filed with the SEC and in our other filings with the SEC and available at including in our Annual Report on Form 10-K. Any forward-looking statements that we make in this announcement speak only as of the date of this press release, and Aclarion assumes no obligation to update forward-looking statements whether as a result of new information, future events or otherwise after the date of this press release, except as required under applicable law. Investor Contacts: PCG Advisory, Inc. 646.823.8656 Media Contacts: Jodi Lamberti 612.812.7477
