Latest news with #MethyleneBlue
Time of India
5 days ago
- Health
- Time of India
What's up with Methylene Blue? Bryan Johnson's latest longevity trend explained
Tech entrepreneur Bryan Johnson who gained fame for his extreme biohacking and longevity pursuits, is currently in the news because of reports that he might either sell or shut down his anti-aging startup. The 47-year-old announced that he does not really need the money, and the company is a "pain in the a**". Bryan Johnson, in the past has shared several scientifically backed anti-aging strategies with daily discipline. Here are five Bryan Johnson anti-aging tips that made news... Silicon Valley biohacker Bryan Johnson recently announced on X (formerly Twitter), 'My urine is now blue. Started Methylene Blue today' sparking curiosity across wellness circles. He's one of several high-profile figures alongside Robert F. Kennedy Jr. and other longevity enthusiasts who hype methylene blue as a longevity and brain-boosting elixir Originally invented in the late 1800s as a textile dye, methylene blue (methylthioninium chloride) found its way into medicine early treating conditions like malaria, urinary infections, and as a vital therapy for methemoglobinemia, a rare blood disorder impairing oxygen delivery. It remains FDA-approved only for this disorder, not for brain-boosting or anti-aging. Bryan Johnson and fellow biohackers claim methylene blue enhances mitochondrial function, sharpens focus, and slows aging by reducing cellular damage. Animal studies and small-scale human trials hint at possible benefits like improved memory or cognitive decline prevention but no robust clinical evidence exists confirming these effects in humans. Is it safe? Low-risk or risky? Methylene blue is generally safe at therapeutic doses typically under 2 mg per kg of body weight. But above 5–7 mg/kg, risks rise significantly, especially serotonin syndrome if mixed with antidepressants (SSRIs, SNRIs, MAOIs). Symptoms can include confusion, tremors, fever, and even fatal brain reactions. Other side effects Users may experience blue or green tinting of skin, urine, even stool, harmless but alarming. Nausea, headache, dizziness, and hemolytic anemia (especially for individuals with G6PD deficiency) have been reported. Quality control issues Supplements labeled 'methylene blue' are unregulated and often unreliable. Some products sold online may even be industrial-grade dye, definitely not for human use. IV treatments at med spas are also risky; unsupervised infusions can lead to contamination or dosing errors. For most people, the basics (good sleep, balanced diet, movement) remain far more proven for brain health than blue dye experiments. If you're curious: consult a qualified physician. Definitely avoid it if you're on antidepressants, pregnant, or have kidney issues.
Globe and Mail
29-07-2025
- Business
- Globe and Mail
Mblue Labs(R) Awarded U.S. Patent for Methylene Blue as Novel UV Sunscreen That Prevents Photo-Aging and Promotes Skin Repair
Bethesda, Maryland--(Newsfile Corp. - July 29, 2025) - Mblue Labs, the biotech company behind the science-driven skincare brand Bluelene has been granted a U.S. Patent for its discovery of Methylene Blue as a multifunctional UV blocking agent that not only protects skin from sun radiation, but also delays skin aging and promotes DNA damage repair. This milestone stems from research that began in 2020, supported by a small business STTR grant from the National Science Foundation (NSF), with the goal to develop a safer, more effective alternative to conventional chemical UV filters like Oxybenzone. Oxybenzone and its derivatives are found in over 70% of today's sunscreens yet are increasingly banned due to their potential human health risks and environmental harms, especially to marine ecosystems. The researchers at Mblue Labs discovered that Methylene Blue, a century old medicine, offers broad-spectrum UV irradiation protection against UVA and UVB rays, neutralizes ROS (Free Radicals), and repairs UV irradiation induced DNA damages, while being safe for coral reefs. Their paper, "Ultraviolet radiation protection potentials of Methylene Blue for human skin and coral reef health " was published in Nature's Scientific Reports. "This patent validates our commitment to redefining sun care with smart, effective, and planet- safe science," says Dr. Kan Cao, Professor at the University of Maryland and Founder and Chief Scientific Officer of Mblue Labs. "Our formula goes beyond surface protection to address the molecular triggers of skin health and aging." In 2022, Mblue Labs launched " Bluevado SunFix", its first anti-aging sunscreen combining FDA-approved physical filters, Zinc Oxide and Titanium Dioxide, with an optimized dosage of Methylene Blue. Bluevado SunFix has garnered a loyal, worldwide following of consumers who seek a sustainable, science-based suncare product with exceptional efficacy. "Our Vision for this novel multifunction sunscreen was deeply rooted in our concern for coral reefs and the skin health of our customers. Bluevado SunFix has been delivering superb broad spectrum UVB/UVA protection and post sun repair, as well as the full anti-aging benefits of our Bluelene Moisturizer with the same cosmetic elegance," says Jasmin EL Kordi, CEO Mblue Labs. This patent adds to the company's IP, which includes the patent for Methylene Blue used topically on human skin to treat age-related symptoms This milestone further positions Bluelene ® as a leader in science-based skincare and a champion of environmentally responsible innovation. The company is now actively pursuing regulatory pathways to get Methylene Blue included in the FDA sunscreen monograph, enabling broader access to its skin- and planet-friendly benefits. About Mblue Labs + Bluelene MBlue Labs provides revolutionary anti-aging technology to consumers around the world. The company's clinical skincare brand Bluelene uses patented ingredient Methylene Blue to repair and protect skin on the mitochondrial level, in the only optimized and trusted concentration on the market. Mblue Labs' research demonstrates Methylene Blue as the new retinol challenger for anti-aging treatments. For more about Dr. Cao's groundbreaking research, see the recently published cover story "The Age of Skin". This research was supported by a National Science Foundation (NSF) Small Business Technology Transfer Grant (Grant: 1842745). This press release does not necessarily represent the views of the NSF. The research for this invention was conducted jointly by researchers at Mblue Labs and the University of Maryland. For media inquiries or product information, contact:
Yahoo
29-07-2025
- Business
- Yahoo
Mblue Labs(R) Awarded U.S. Patent for Methylene Blue as Novel UV Sunscreen That Prevents Photo-Aging and Promotes Skin Repair
Bethesda, Maryland--(Newsfile Corp. - July 29, 2025) - Mblue Labs, the biotech company behind the science-driven skincare brand Bluelene has been granted a U.S. Patent for its discovery of Methylene Blue as a multifunctional UV blocking agent that not only protects skin from sun radiation, but also delays skin aging and promotes DNA damage repair. This milestone stems from research that began in 2020, supported by a small business STTR grant from the National Science Foundation (NSF), with the goal to develop a safer, more effective alternative to conventional chemical UV filters like Oxybenzone. Oxybenzone and its derivatives are found in over 70% of today's sunscreens yet are increasingly banned due to their potential human health risks and environmental harms, especially to marine ecosystems. The researchers at Mblue Labs discovered that Methylene Blue, a century old medicine, offers broad-spectrum UV irradiation protection against UVA and UVB rays, neutralizes ROS (Free Radicals), and repairs UV irradiation induced DNA damages, while being safe for coral reefs. Their paper, "Ultraviolet radiation protection potentials of Methylene Blue for human skin and coral reef health " was published in Nature's Scientific Reports. "This patent validates our commitment to redefining sun care with smart, effective, and planet- safe science," says Dr. Kan Cao, Professor at the University of Maryland and Founder and Chief Scientific Officer of Mblue Labs. "Our formula goes beyond surface protection to address the molecular triggers of skin health and aging." In 2022, Mblue Labs launched "Bluevado SunFix", its first anti-aging sunscreen combining FDA-approved physical filters, Zinc Oxide and Titanium Dioxide, with an optimized dosage of Methylene Blue. Bluevado SunFix has garnered a loyal, worldwide following of consumers who seek a sustainable, science-based suncare product with exceptional efficacy. "Our Vision for this novel multifunction sunscreen was deeply rooted in our concern for coral reefs and the skin health of our customers. Bluevado SunFix has been delivering superb broad spectrum UVB/UVA protection and post sun repair, as well as the full anti-aging benefits of our Bluelene Moisturizer with the same cosmetic elegance," says Jasmin EL Kordi, CEO Mblue Labs. This patent adds to the company's IP, which includes the patent for Methylene Blue used topically on human skin to treat age-related symptoms This milestone further positions Bluelene ® as a leader in science-based skincare and a champion of environmentally responsible innovation. The company is now actively pursuing regulatory pathways to get Methylene Blue included in the FDA sunscreen monograph, enabling broader access to its skin- and planet-friendly benefits. About Mblue Labs + Bluelene MBlue Labs provides revolutionary anti-aging technology to consumers around the world. The company's clinical skincare brand Bluelene uses patented ingredient Methylene Blue to repair and protect skin on the mitochondrial level, in the only optimized and trusted concentration on the market. Mblue Labs' research demonstrates Methylene Blue as the new retinol challenger for anti-aging treatments. For more about Dr. Cao's groundbreaking research, see the recently published cover story "The Age of Skin". This research was supported by a National Science Foundation (NSF) Small Business Technology Transfer Grant (Grant: 1842745). This press release does not necessarily represent the views of the NSF. The research for this invention was conducted jointly by researchers at Mblue Labs and the University of Maryland. For media inquiries or product information, contact: More at: and @getbluelene on social Media Contact Information Jasmin El KordiJasmin@ To view the source version of this press release, please visit Sign in to access your portfolio
The Hindu
20-07-2025
- Science
- The Hindu
Team makes powerful water filter with help from light, vibrations
Scientists from the Institute of Nano Science and Technology (INST) in Mohali, IIT-Dharwad, and IIT-Kharagpur have designed a cheap, reusable water filter. Industrial plants release dyes such as Congo Red and Methylene Blue into rivers and groundwater, from where they can cause stomach, skin, and breathing illnesses. Ozone, Fenton chemistry and other methods work to clean the water, but they burn through chemicals and electricity, expanding cost and the carbon footprint. The new filter has been designed to sidestep these and other problems. Its development was reported in a paper in the July edition of Nano Energy. The researchers first 3D printed thin, sponge-like sheets of polylactic acid (PLA), a biodegradable plastic often used in compostable cups. PLA is naturally water-repelling, so the team soaked each sheet in a mild sodium-hydroxide solution to make it water-loving. Next, they made nanoparticles of bismuth ferrite (BFO) and dipped the prepared PLA sheets into a BFO ink. Treated sheets stayed strong through five reuse cycles, losing only about 3% of their cleaning power. Under visible light, the BFO acted like a solar-powered catalyst that split water molecules and created highly reactive radicals that shred organic dye molecules. And when shaken by ultrasound, BFO's piezoelectric nature generated an internal electric field that drove the same radical-making reactions even in the dark. Combining both light and vibration yielded piezo-photocatalysis, a process that worked day or night. During tests, when light and vibration were used together, the filter removed about 99% of Congo Red and 74% of Methylene Blue in 90 minutes. It also partially cleaned real wastewater collected from a textile plant. To understand its performance, the authors turned to machine-learning regression models. They fed the computer thousands of experimental data points, including dye concentration, catalyst amount, light intensity, and ultrasound frequency. Modern algorithms such as random forests, XGBoost, and an artificial neural network learned how these factors interacted. The best models closely matched the experimental results, which they hadn't seen, well enough to prove artificial intelligence could accurately forecast how fast the dyes vanished in different conditions. 'We are thinking of scaling up production and using the filter near treatment plants, where water bodies are regularly polluted,' Aviru Basu, INST scientist and corresponding author of the paper, said, adding that the team looks forward to its use in Jal Nigam and Namami Gange projects as well. 'Dr. Adreeja Basu, a plant biotechnologist and professor at Chandigarh University, is also helping us a lot in our efforts to make this product more sustainable using plant-derived products,' Dr. Aviru Basu added.
Indian Express
11-07-2025
- Science
- Indian Express
INST Mohali develops AI-powered solar filter to purify 99% toxic wastewater
In a significant breakthrough for Punjab's water pollution crisis, scientists at the Institute of Nano Science and Technology (INST), Mohali, have developed an AI-powered, solar-assisted filtration system capable of removing up to 99% of hazardous chemicals from wastewater. As the state continues to grapple with the discharge of 764 million litres of untreated industrial and domestic sewage daily into the Sutlej via Ludhiana's heavily polluted Buddha Nullah, the innovation offers a ray of hope. 'Our technique targets highly toxic industrial dyes like Congo Red (CR) and Methylene Blue (MB), commonly used in textile and pharmaceutical industries,' lead researcher Dr. Aviru Basu told The Indian Express. 'These dyes not only discolor water but also cause skin disorders, respiratory problems, and long-term health issues.' The filtration system uses a hybrid 3D-printed scaffold made from biodegradable polylactic acid (PLA), coated with bismuth ferrite (BiFeO₃) — a solar-activated catalyst. 'Unlike traditional wastewater treatments like electrochemical or ozone processes, which are expensive and energy-intensive, our technology is low-cost, eco-friendly, reusable, and powered by renewable energy,' said Dr. Basu. The innovation, called Piezo-Photocatalysis, activates the catalyst using a combination of solar light and gentle vibrations, allowing it to function effectively even under changing weather conditions. Lab results showed a 98.9% removal of Congo Red and 74.3% of Methylene Blue, surpassing many existing advanced water treatment methods. The system was successfully tested on real wastewater samples collected from a large industrial drainage point in Jaipur, where over 100 factories discharge effluents. 'The results were very satisfactory,' said Dr. Basu. To boost performance further, the team integrated Artificial Neural Networks (ANN) — a machine learning model — to accurately predict how the system would behave under different environmental and pollutant conditions. 'Our AI model has up to 99% prediction accuracy,' Dr. Basu added. INST is now collaborating with plant biotechnologist Dr. Adriza Basu of Chandigarh University to improve the system's long-term sustainability. The project, funded by the Department of Science and Technology (DST), has been published in Nano Energy, a journal by Elsevier. Dr. Basu believes the scalable technology could be a game-changer for rural and peri-urban areas. 'If the Punjab government adopts this, we could safely discharge treated water into the Sutlej. It would be a giant leap toward cleaning Buddha Nullah and addressing the state's toxic water crisis,' he said.
