Latest news with #RohitShetty
Time of India
a day ago
- Business
- Time of India
Tears don't just reveal your emotions. New tear test kit can detect several diseases too
Byline: Mini P Thomas Just a few teardrops can reveal volumes about a range of medical conditions, from cancer to Alzheimer's disease and retinopathies. India has been developing its own tear-based point-of-care diagnostic kit at GROW Research Laboratory in Narayana Nethralaya, Bengaluru, for which clinical trials are on. Dr Rohit Shetty, director of Narayana Nethralaya and GROW Research Laboratory, tells Mini P Thomas how tears can revolutionise healthcare. What makes tears a potential diagnostic tool? A lot of inflammatory changes happen in the eyes and the body before the onset of diseases and tear analysis can pick them up. Tears can serve as an early warning system, making them an excellent tool for early diagnosis of rheumatoid arthritis (RA) and many other inflammatory diseases even before changes manifest in the bones. Moreover, tear-based tests are non-invasive and less expensive than conventional diagnostic tests. How do you do tear tests, and when will they be available in the market? The most straightforward method of collecting tears is by using small pieces of sterile paper. The tear analysis results arrive at your clinic within 90 minutes of collection. We are now in the last leg of certification from the government. And we are hoping that by Feb 2026, the tear-based kits will be commercially available. Besides RA, what other diseases can tear fluid detect? Currently, there are no routine predictive markers available for Alzheimer's other than changes seen in an MRI. By the time those changes manifest, it's too late. But we have successfully identified a protein in tears called Tau, which is very specific to Alzheimer's disease. Early detection of these proteins could be crucial to prevent irreversible brain damage. We are currently collaborating with neurologists to explore how tear analysis might help in early detection and prevention. We have also done some work on breast cancer and genital, urinary and ovarian cancers using tear samples, where we looked at whether increase in certain secondary factors has a role in early prediction. Tear analysis can play a key role in the management of dry eyes and diabetes as well. Myopia or shortsightedness has reached epidemic proportions in India. Diagnostic tools using tear samples show potential for detecting children prone to myopia. How can the teardrop analysis technique prevent myopia in children? The global rise in myopia cases has become a significant health concern. Tear analysis can detect dopamine levels in tears, which aids in myopia prediction. Children with reduced tear dopamine, a neurotransmitter in the brain, can benefit from sunlight exposure, potentially lowering their myopia risk. Parents should encourage their kids to spend at least two hours outdoors every day to significantly reduce their risk of myopia. Studies indicate that elevated dopamine concentrations contribute to better management of myopia. Retinopathy of prematurity (ROP) is one of the most common causes of blindness in preterm babies. Through tear analysis, we can identify babies who are likely to have ROP by detecting certain biomarkers in their tears, which tell us which of these infants will go into a progression. This could be a fantastic community-based project in the future. What about dry eyes, also a significant health concern in India? It is estimated that by 2030, one in two urban Indians will be affected by dry eye disease, which could affect their quality of life and work efficiency. Often, non-specific medications are prescribed for dry eyes which fail to address the actual immunological changes, leaving the condition untreated. Now, we can detect elevated immuno-inflammatory markers using tear samples and target them with specific eye drops, offering personalised and customised treatment. Analysis of tear biomarkers enables swift diagnosis, targeted and personalised treatment, and promotes faster recovery. This results in reduced medical expenses and quicker relief for patients. One step to a healthier you—join Times Health+ Yoga and feel the change
Time of India
3 days ago
- Entertainment
- Time of India
When Ajay Devgn and Rohit Shetty spoke about Bollywood's class divide
and are one of the most successful actor-director duos in Hindi cinema. Out of Rohit Shetty's 14 films, 12 starred Ajay. These include all four movies from the comedy series 'Golmaal' and the four films in the cop universe, starting with 'Singham' in 2011 and going up to 'Sooryavanshi' in 2021. Tired of too many ads? go ad free now In 2014, before the release of Singham Returns, Ajay Devgn and Rohit Shetty spoke about the class divide in the Hindi film industry during a promotional interview with Film Companion. They referred to a message Ajay had sent to Rohit back in 2011 on Karan Johar's chat show Koffee With Karan, where he said:"I am so happy that people who abused your kind of movies want to work with you now", the actor and the filmmaker were asked if a class divide exists within Bollywood. The Tanhaji star, Ajay Devgn, said he personally hadn't faced the issue but had heard people call Golmaal 'trash cinema.' He pointed out the irony that those same people later approached Rohit Shetty to direct films for them, realizing that they needed such so-called 'trash cinema' to stay relevant in the industry. Rohit Shetty, who also hosts the popular reality show Khatron Ke Khiladi, said he has no ego or arrogance about his work and believes he's simply making films for his audience. He shared that many people have now come around, saying he's not doing anything wrong or harmful. Referring to the earlier criticism from the elite crowd, Rohit humorously compared himself to Amitabh Bachchan's 'bad guy' character from Deewar (1975), calling the critics Nirupa Roy and the elite Shashi Kapoor. He concluded by saying he's happy being Amitabh—the so-called bad guy—at the end of the day. In November last year, Rohit Shetty's Sooryavanshi revived the Indian box office, earning nearly ₹200 crores after theatres reopened nationwide following a two-year Covid-19 lockdown. Rohit and Ajay have also hinted at the next film in their cop universe, Singham 3, though an official announcement is still awaited. Rohit Shetty
Time of India
5 days ago
- Entertainment
- Time of India
Celebrities Unite for ‘Tik Tik Plastic 3.0' Campaign Against Pollution
Celebrities Unite for 'Tik Tik Plastic 3.0' Campaign Against Pollution Source: A star-studded campaign 'Tik Tik Plastic 3.0' has been launched to tackle plastic pollution globally. Filmmaker Rohit Shetty and environmentalist Asif Bhamla lead the initiative, featuring actors Ajay Devgn, Sharvari Wagh, and Seema Singh. The campaign uses impactful short films to engage youth and spread awareness about reducing plastic waste. Timed ahead of World Environment Day 2025, this effort marks a shift by the Bhamla Foundation from music videos to storytelling, aiming to inspire collective action for a cleaner, sustainable future.
Pink Villa
26-05-2025
- Entertainment
- Pink Villa
‘In my head, I believe…': John Abraham shares why he's not fully convinced about doing OTT projects
The OTT platform has emerged as a top choice for both audiences and major celebrities, with many big names making their digital debuts. However, it appears that actor John Abraham isn't in a rush to join the trend. In a recent interview, the Dhoom star shared his perspective on the matter and said, "In my head, I believe, I was made for the big screen." John Abraham on why he is not doing OTT projects In a conversation with Hindustan Times, John Abraham expressed his reservations about working in the OTT space. He reportedly pointed out that venturing into the digital medium requires a large operational setup and a dedicated team, yet creators often don't retain ownership of the intellectual property. According to him, the revenue earned is usually offset by operational costs, making the effort less worthwhile. He added that most people involved in OTT would agree with this perspective, which is why he doesn't find it practical to pursue web series at the moment. However, he acknowledged that he would be open to producing a web series if he came across a compelling story that genuinely resonated with him. The Vedaa actor clarified that his interest would stem from a desire to share a meaningful narrative, rather than to pursue it as a business venture. This, he explained, is why he has not taken on any OTT projects as a producer so far. As for appearing in web content as an actor, John Abraham maintained that while he wouldn't rule it out entirely, he currently has no intention of doing a series or an original film for an OTT platform. He stated that his focus remains on the big screen, which he believes is where he truly belongs. Although he holds great respect for digital platforms, especially given the high-quality international offerings and standout Indian productions like Paatal Lok, he doesn't yet see himself fitting into that space. On the work front, John Abraham has teamed up with Rohit Shetty for his upcoming project. The yet-to-be-titled film is a gripping thriller based on the life of former Mumbai Police Commissioner Rakesh Maria. The story promises to be intense, highlighting key moments from Maria's career, from his investigations into the 1993 Bombay blasts and the 26/11 attacks to his confrontations with the underworld.
India.com
15-05-2025
- Entertainment
- India.com
India's biggest flop film lost Rs 90 crore, had many stars, was a remake of..., lead actor played double role for the first time, earned just Rs...
India's biggest flop film lost Rs 90 crore, had many stars, was a remake of..., lead actor played double role for the first time, earned just Rs... Ranveer Singh has enjoyed a successful career with several box office hits like Padmaavat, Simmba and more. At the same time, he has faced setbacks with few flop films. The biggest flop of his career came with the 2022 release Cirkus. Directed by Rohit Shetty, the period comedy drama marked the first time Ranveer Singh took on a double role in his career. Varun Sharma also portrayed dual role in the film. Cirkus also starred leading actresses Pooja Hegde and Jacqueline Fernandez, as well as, bunch of comedians including Johnny Lever, Sanjay Mishra, Siddhartha Jadhav, Murali Sharma, Vrajesh Hirjee, and Tiku Talsania.
