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NAD aging: Benefits, risks, and more
NAD aging: Benefits, risks, and more

Medical News Today

time27-05-2025

  • Health
  • Medical News Today

NAD aging: Benefits, risks, and more

Medically reviewed by Shilpa Amin, M.D., CAQ, FAAFP, Family Medicine , Women's Health , Geriatrics , Integrative Medicine , Clinical Research , Jurisprudence , — Written by Louise Morales-Brown on May 21, 2025 Benefits for older adults Possible risks Healthy aging tips Summary Nicotinamide adenine dinucleotide (NAD) is a coenzyme that plays a key role in many biological processes. More research is necessary, but some studies suggest that NAD may help reduce the risk of aging-related diseases. NAD is an essential enzyme that has a role in many important cell functions, such as energy metabolism, DNA repair, and cellular health. NAD levels naturally decline with age and may relate to various signs of aging, such as lower energy, impaired cellular repair, and higher risk of age-related diseases. As such, some health experts believe that increasing NAD may help promote longevity and slow the aging process. However, there is currently no conclusive evidence that NAD supplementation can slow aging, and more research is necessary to understand its possible benefits. Stefania Pelfini, LaIn 1937, a biochemist called Conrad Elvehjem first established a link between low levels of NAD and aging. Since, researchers found that NAD levels decrease with age, as well as exposure to certain stressors and disease. As such, some evidence suggests that lower NAD levels may result in aging and age-related disease. Due to its role in the aging process, growing research indicates that boosting NAD may provide health benefits and delay signs of aging. Healthy lifestyle choices, such as regular exercise, sufficient sleep, and a balanced dietary plan may help to extend life expectancy, possibly due to increasing NAD levels. Therefore, it may be possible to get similar benefit by increasing NAD levels through taking NAD precursors or boosters. At present, most research into NAD precursors, such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), is in the form of animal studies. The results of these studies suggest that NAD precursors could help to extend health span and reduce premature aging in animal models. A 2023 review indicates that NAD precursors are generally safe and may have the potential to support graceful aging in humans. However, the review also emphasizes that further research is necessary in humans, particularly to determine the possible effects and safety of these supplements. Although NAD supplements are showing promise as agents that support graceful aging, there are still some concerns about their safety profile and possible long-term effects. For example, a 2022 review highlights potential concerns about adverse effects on several organs, such as the kidney, liver, pancreas, and stomach. However, the review also notes that other research suggests that NAD could provide several benefits for these organs. As such, more research is still necessary to establish the safety profile, appropriate dosages, and long-term effects of these supplements. Researchers must also determine the most effective way to administer these products, which could include dietary supplements, injections, or topical solutions. Instead, it recognizes NMN as a drug due to its potential ability to support graceful aging. Therefore, it must receive FDA approval for both safety and effectiveness before manufacturers can market it as a product that supports graceful aging. Therefore, it is advisable for a person to consult their doctor before taking any NAD supplements. Many factors can influence aging. Some of these factors, such as genetics, are not modifiable. However, others are modifiable, meaning that people can make certain lifestyle choices to help prevent some health problems and promote healthy aging. Some tips for healthy aging can include : following a healthy, balanced dietary plan regular physical activity maintaining a healthy weight to help prevent health problems getting sufficient sleep keeping the mind stimulated and active, through memory games, learning new skills, reading, and playing games maintaining mental health, through socializing, relaxation techniques, and mindfulness regularly participating in enjoyable activities, such as hobbies, social, and leisure activities playing an active role in healthcare, such as attending regular checkups, vaccines, and health screenings avoiding or reducing activities that can be harmful to health, such as smoking or consuming alcohol taking steps to prevent injury, including safe driving and reducing the risk of falls Nicotinamide adenine dinucleotide (NAD) is an important coenzyme that likely plays a role in the aging process. As people age, their levels of NAD naturally decline, which may increase their risk of age-related diseases. Growing research in animal models suggests that boosting NAD levels may help to improve life span and prevent or delay certain health conditions. However, more research in humans is necessary to establish whether NAD supplements are safe and if they can provide health benefits. Supplements Seniors / Aging Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Bhasin S, et al. (2023). Nicotinamide adenine dinucleotide in aging biology: Potential applications and many unknowns. Braidy N, et al. (2018). Role of nicotinamide adenine dinucleotide and related precursors as therapeutic targets for age-related degenerative diseases: Rationale, biochemistry, pharmacokinetics, and outcomes. Conlon NJ. (2021). The role of NAD+ in regenerative medicine. Covarrubias AJ, et al. (2021). NAD + metabolism and its roles in cellular processes during ageing. Healthy aging. (2024). Healthy aging at any age. (2024). Henderson JD, et al. (2024). The use of a systems approach to increase NAD + in human participants. Igbal T, et al. (2024). The therapeutic perspective of NAD + precursors in age-related diseases. Lam C, et al. (2023). Food, drug, and cosmetic act. McReynolds MR, et al. (2021). Age-related NAD + decline. Nadeeshani H, et al. (2022). Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns. Poljsak B, et al. (2020). Healthy lifestyle recommendations: Do the beneficial effects originate from NAD + amount at the cellular level? Song Q, et al. (2023). The safety and antiaging effects of nicotinamide mononucleotide in human clinical trials: An update. Wrinkle treatments and other anti-aging products. (2022).

Healthy aging: 7 strategies for optimizing well-being
Healthy aging: 7 strategies for optimizing well-being

Medical News Today

time20-05-2025

  • Health
  • Medical News Today

Healthy aging: 7 strategies for optimizing well-being

Medically reviewed by Shilpa Amin, M.D., CAQ, FAAFP, Family Medicine , Women's Health , Geriatrics , Integrative Medicine , Clinical Research , Jurisprudence , — Written by Amy Murnan on May 9, 2025 Healthy aging involves a range of strategies that keep the mind and body as healthy as possible as a person enters their later years. These strategies include nutrition, exercise, and social connection. Healthy aging practices may help prevent or delay some of the conditions associated with aging, such as cognitive impairment and osteoporosis. They can also help a person maintain a higher quality of life for longer, allowing for more independence and greater well-being across their life span. Read on to learn the definition of healthy aging and ways to practice it. Sergey Narevskih/Stocksy Healthy aging involves taking steps to promote health throughout the life span, especially in older age. This may help with: maintaining independence preventing health conditions improving quality of life increasing longevity People can start taking steps toward healthy aging at any time , whether they are younger or older. The World Health Organization (WHO) emphasizes that healthy aging is not exclusive to people without any health conditions. This approach can also help those who have preexisting conditions or disabilities. Below are some of the factors that help with healthy aging. Nutrition is important for growth and development in childhood and continues to be important throughout life. While there is no single 'best' diet that will suit every person, a 2025 analysis of eight dietary patterns found that people who ate more of the following types of foods were the most likely to experience healthier aging: In contrast, people who consumed more sodium, sugary drinks such as soda, and red or processed meats were less likely to experience healthy aging. To start a diet that promotes healthy aging, people may find it helpful to make one change at a time or to swap less nutritious foods for more nutritious alternatives. People who have difficulty getting enough sun exposure, eat restricted diets, or have problems with nutrient absorption may need to talk with a doctor about taking supplements. » Read more: What is the required daily intake of vitamins and minerals? keep muscles strong increase bone health improve mood and sleep quality improve balance, reducing the risk of falls and injuries lower blood pressure reduce the risk of dementia, depression, diabetes, heart disease, stroke, and eight types of cancer reduce the risk of death from any cause Examples of aerobic exercise include: brisk walking jogging or running cycling dancing Examples of strengthening exercises include: weightlifting bodyweight exercises, such as pushups some types of tai chi and yoga hobbies that involve physical labor, such as gardening People should aim to exercise at least 3 days each week, for a total of 150 minutes of moderate to vigorous activity per week. However, it is important to remember that any movement is better than none. If a person cannot exercise consistently or for very long, starting with light exercise or short workouts can still bring significant benefits. Both exercise and nutrition also benefit a person's mental health and cognitive function. Here are some other ways people can look after their brain health as they age: Most adults need 7 to 9 hours of sleep per night, but many factors can interfere with this, such as: People who have difficulty sleeping or staying asleep or do not feel refreshed when they wake up may want to speak with a doctor about how to address these issues. » Learn more: Tips for sleeping better Loneliness and isolation can harm health in people of any age. These issues are especially common in older adults, but also in adolescents, and have links to higher rates of many conditions . Creating social connections has tangible benefits for health and well-being. Social connections can reduce loneliness, provide meaning in a person's life, and give them a support network. Ways to reduce isolation include: talking with neighbors using technology to keep in touch with friends or family joining group activities or exercise classes joining a community organization or volunteering adopting a pet » Learn more: Loneliness and how to prevent it According to a 2022 review of past research, long-term stress may speed up the aging process and lead to the earlier onset of several health conditions, such as cardiovascular disease. Stress can also contribute to depression, which is common in older adults. According to the WHO, mental health conditions account for 10.6% of the years older adults live with disability. Decreasing stress and treating mental health conditions can lead to substantial improvements in mood and quality of life. Practices that can support mental well-being at any age include: Reducing avoidable stress: Where possible, reduce sources of stress that are not necessary. This could involve saying 'no' more often, setting healthy boundaries, or solving problems. Where possible, reduce sources of stress that are not necessary. This could involve saying 'no' more often, setting healthy boundaries, or solving problems. Learning coping skills: Mindful activities such as meditation, deep breathing exercises, and relaxation techniques can reduce stress when it occurs. Mindful activities such as meditation, deep breathing exercises, and relaxation techniques can reduce stress when it occurs. Practicing self-care: All of the above strategies, including diet, exercise, and sleep, can benefit a person's mental health. All of the above strategies, including diet, exercise, and sleep, can benefit a person's mental health. Avoiding substance use: While some people feel that alcohol or tobacco may help them temporarily cope with stress, these substances have a negative effect on mood and physical health over time. While some people feel that alcohol or tobacco may help them temporarily cope with stress, these substances have a negative effect on mood and physical health over time. Reaching out for help: Seek support for stress that is unavoidable or overwhelming or for signs of mental health conditions. » Read more: How to improve your mental health According to the WHO, an estimated 75% of the changes in ability or health that people can experience in older age are related to the advantages or disadvantages they have had in life. This means that a person's environment and circumstances play a large role in determining their future health. People may not always be able to control these factors, but there are things within their control. For example, they may be able to: try at-home workouts or video tutorials if it is not safe to exercise outside volunteer for, or buy food from, community gardens or co-ops learn recipes for healthy meals on a budget use mobile health services or screenings if they cannot drive or if they live in a rural area without easy access to healthcare facilities look into low cost mental health support access help from community organizations, programs, and support networks Preventive healthcare can reduce the risks of certain health conditions as a person gets older. People can make the most of it by: If a person has a family history of certain conditions, they can also let doctors know about this, as it may influence their decisions around screening or tests. A list of preventive and screening services is available on the Medicare website. Healthy aging can help people maintain better health for longer, improving their quality of life and independence as they age. People can start practicing habits that promote healthy aging at any time, no matter their age or physical ability. These habits can involve making dietary changes, reducing stress, getting enough sleep, and exercising regularly. Those who have difficulty making these changes may be able to reach out to healthcare professionals or their community for help.

HCA Florida Healthcare to bring stand-alone ER to Nassau County
HCA Florida Healthcare to bring stand-alone ER to Nassau County

Yahoo

time29-03-2025

  • Health
  • Yahoo

HCA Florida Healthcare to bring stand-alone ER to Nassau County

HCA Florida Memorial Hospital has announced the ribbon cutting of its first freestanding emergency room in Nassau County. >>> STREAM ACTION NEWS JAX LIVE <<< [DOWNLOAD: Free Action News Jax app for alerts as news breaks] Located at the corner of I-95 ad State Road 200, the ribbon cutting will begin at 9:00 a.m. on Monday, March 31. 'The goal of the new space is to provide better access for patients needing emergency care to the Nassau County region,' said Reed Hammond, Chief Executive Officer of HCA Florida Memorial Hospital in Jacksonville, FL. 'As a part of HCA Florida Healthcare, the largest healthcare family in Florida, Nassau County is now connected to a wide spectrum of statewide healthcare resources previously not available.' HCA Florida Yulee Emergency will serve Yulee, Callahan, Fernandina Beach, Amelia Island, nearby South Georgia, and Jacksonville residents. Services provided include: Emergency care services 10 private rooms One Trauma Bay Minimally invasive diagnostics CT scan Ultrasound X-ray Board-certified emergency physicians Emergency room nurses Easy access to parking 24-7 Availability 'By providing an Emergency Room in the Yulee area, we are listening to what residents need,' said Shilpa Amin, MD, Director of Emergency Services for HCA Florida Memorial Hospital. 'We are excited to offer our high level of healthcare expertise and compassionate care to Nassau County.' [SIGN UP: Action News Jax Daily Headlines Newsletter] Click here to download the free Action News Jax news and weather apps, click here to download the Action News Jax Now app for your smart TV and click here to stream Action News Jax live.

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