Latest news with #SolaDiagnostics
Yahoo
04-03-2025
- Health
- Yahoo
New Covid-style test for womb cancer could soon be available on NHS
Women who are experiencing signs of womb cancer can soon be offered a less invasive test to rule out disease after it was given the green light for use in the UK. Traditionally, women with signs of womb cancer would need a transvaginal ultrasound scan or a hysteroscopy – where a tube with a camera in it is used to look inside the womb – to confirm or rule out womb cancer. But the new test, WID-easy, uses some of the same technology used in Covid PCR (polymerase chain reaction) tests. It will involve a simple swab, which is sent off to a laboratory for analysis. Scientists then look for changes in the DNA that indicate whether womb cancer is present or not. If the test indicates that a woman has womb cancer, then the woman would need a biopsy to confirm or rule out the diagnosis. The new test, by University College London (UCL) spinout company Sola Diagnostics, has been approved for use in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA) for women over the age of 45 who have abnormal uterine bleeding. This means that it is immediately available to private clinics, and it is hoped that it will one day be made available for widespread use on the NHS. Commenting on the potential roll out of the new test Athena Lamnisos, chief executive of The Eve Appeal, says: "Currently in the UK, the tests to investigate abnormal bleeding and check for womb cancer can cause stress and discomfort. The usual test is a hysteroscopy, which many find painful and invasive. "A test which is less painful and more acceptable is to be welcomed by many. The WID-easy test could enable the many thousands of women who experience abnormal bleeding, and where cancer needs to be ruled out, to potentially avoid painful tests like hysteroscopies and have their minds put at rest sooner, saving them from unnecessary stress." The new test comes as a leading health expert warned women could be ignoring some potential key symptoms of womb cancer, due to a lack of awareness about what to look out for. Research has revealed that more than 22,000 women in the UK are diagnosed with gynaecological cancer every year – that's around 60 diagnoses every day and more than 400 women a week. One of the five gynaecological cancers is womb cancer (aka uterine or endometrial cancer). According to Cancer Research UK, around 9,800 women are diagnosed with womb cancer every year, making it the fourth most common cancer in UK women. Despite affecting so many, few women are aware of the potential symptoms, but having an awareness about womb cancer and other gynaecological cancers could mean the difference between an early diagnosis and leaving it too late. Yahoo UK previously spoke to Valentina Milanova, women's health expert and founder of gynae health company, Daye, to throw a light on some of the most common symptoms of womb cancer women should be looking out for. From painful sex, to unexpected vaginal bleeding and irregular menstruation, Milanova believes if more women could spot these signs, they might get diagnosed and receive treatment sooner. Womb cancer, also known as endometrial or uterine cancer, is cancer that affects the womb. According to the NHS, the womb (uterus) is where a baby grows during pregnancy. Most womb cancer usually starts in the lining of the womb (endometrium). Womb cancer typically presents with the following symptoms: Unusual vaginal bleeding, typically happening in between periods, after menopause, after sex or urination. Irregular menstruation, defined as unforeseen changes to the patient's menstrual cycle, heavier and longer periods, or breakthrough bleeding in between periods. Pelvic pain, which is often trivialised and ignored, but can be a symptom of gynaecological cancers. Painful sex is another symptom that women are taught to normalise, but can be a symptom of womb cancer. Pelvic pain and pressure are typically a symptom of endometrial cancer progressing. Larger uterus, which is seen in some cases where the endometrial cancer is causing an enlarged lower abdomen/pelvis. But Milanova says it is important to note that while these are common symptoms of womb cancer, they can also be caused by various other conditions that are not cancerous, such as hormonal imbalances, uterine fibroids, or polyps. "This is one reason why some patients may miss or dismiss these symptoms initially," she adds. According to Milanova there are several reasons why many women and assigned female at birth (AFAB) individuals may miss symptoms including: Menopause: Postmenopausal bleeding is often a red flag for womb cancer, but some patients may not realise they have reached menopause and therefore disregard the bleeding as a warning sign. Assuming it's normal: Due to the trivialisation of gynaecological pain, many women may assume that irregular periods or changes in menstrual bleeding are normal, which would lead to them not seeking medical attention. Mistaking endometrial cancer for something else: Symptoms like pelvic pain or weight loss can be attributed to various non-cancerous conditions, leading to a delay in seeking a cancer diagnosis. Fear: The fear of a cancer diagnosis or denial of potential health issues can lead some individuals to delay seeking medical help. While we don't know what causes most womb cancers, there are some factors that could increase your risk of developing it. Age: Womb cancer is most common in postmenopausal women, with the majority of cases diagnosed after age 50. Hormonal Factors: Excess oestrogen exposure, either due to obesity or certain medical conditions like polycystic ovary syndrome (PCOS), can increase the risk. Obesity: Obesity is a significant risk factor for womb cancer because it can lead to increased oestrogen levels. Diabetes: Some studies suggest a link between type 2 diabetes and an increased risk of womb cancer. It's important for every patient, especially those in the high-risk categories, to be aware of the symptoms of womb cancer and seek medical support if they experience any concerning signs. Early detection and treatment can significantly improve the outcome for individuals with womb cancer. Read more about womb cancer: Symptoms of the 5 gynaecological cancers women should never ignore (Yahoo Life UK, 7-min read) Woman, 58, who thought she was 'in menopause' diagnosed with womb cancer (Birmingham Live, 3-min read) New womb cancer treatment to benefit hundreds of patients each year (PA, 3-min read
Telegraph
04-03-2025
- Health
- Telegraph
Covid-style tests for womb cancer to be offered
Women with signs of womb cancer can be offered a less invasive test to rule out disease after it was approved for use in the UK. The new test, WID-easy, uses some of the same technology used in Covid PCR (polymerase chain reaction) tests. Traditionally, women with signs of womb cancer would need a transvaginal ultrasound scan or a hysteroscopy – where a tube with a camera is used to look inside the womb to confirm or rule out disease. The new PCR test is a simple swab, which is sent off to a laboratory for analysis. Scientists then look for changes in the DNA that indicate whether womb cancer is present. If the test indicates that a woman has womb cancer, then she would need a biopsy to confirm or rule out the diagnosis. Potential for widespread use The test, developed by Sola Diagnostics, has been approved in the UK by the Medicines and Healthcare products Regulatory Agency for use by women over 45 who have abnormal uterine bleeding. This means that it is immediately available to private clinics, and it is hoped that it will be made available for widespread use in the NHS. Analysis of the test, which was developed by researchers from University College London (UCL) and the University of Innsbruck, was published in Lancet Oncology in 2023. 'The... test delivers fast results and shows improved performance compared with a combination of imaging index tests,' the authors wrote at the time. The test also significantly reduces the number of false positives, which could mean fewer healthy women would be sent to have invasive hysteroscopy or biopsy procedures. The inventor of the test, Professor Martin Widschwendter, from UCL's Institute for Women's Health and the University of Innsbruck in Austria, said: 'The WID-easy test is the first test of its kind in the UK – using a simple swab method to detect womb cancer. 'We are proud to have developed a test that addresses an urgent gap in women's health and performs well across all women.' 'Minds put at rest sooner' Athena Lamnisos, chief executive of The Eve Appeal, a leading gynaecological cancer charity, said: 'Currently in the UK, the tests to investigate abnormal bleeding and check for womb cancer can cause stress and discomfort. The usual test is a hysteroscopy, which many find painful and invasive. 'A test which is less painful and more acceptable is to be welcomed by many. 'One of the key groups who may benefit from this test are black women who more often receive a late-stage diagnosis for this cancer… 'The WID-easy test could enable the many thousands of women who experience abnormal bleeding, and where cancer needs to be ruled out, to potentially avoid painful tests like a hysteroscopy and have their minds put at rest sooner, saving them from unnecessary stress.'
