Latest news with #anti-aging
CNN
05-08-2025
- Health
- CNN
Is salmon sperm the secret to amazing skin? We asked derms about the buzzy beauty trend
Salmon sperm skin care quick picks Serum: Rejuran Advanced Anti-Aging Retinol + c-PDRN Serum Under-eye patches: Abib PDRN Retinal Eye Patch Moisturizer: Gangnam Glow Rejunol Mucin PDRN Facial Cream Sheet mask: Medicube Salmon PDRN Pink Collagen Jelly Gel Mask Neck cream: Valmont V-Lift Neck Cream If salmon sperm skin care is a phrase you've heard before, it was likely within the context of the anti-aging facials celebrities can't seem to get enough of right now. With claims of instantly glowing and youthful skin, it's no wonder the K-beauty ingredient has become a beauty trend in and of itself, spreading beyond in-office treatments into face moisturizers, serums, face masks and beyond. So, what exactly is salmon sperm doing in our skin care, and what are the benefits of this seemingly off-putting ingredient? I consulted four experts, including three dermatologists and a licensed esthetician, to answer the questions on all of our minds as well as share some of their top product recommendations you can try out for yourself. First popularized in South Korea, salmon sperm skin care refers to skin care products that include salmon-derived polydeoxyribonucleotide (PDRN), or purified DNA fragments. 'PDRNs are polynucleotides that are derived from salmon sperm,' Dr. Michelle Henry, board-certified dermatologist and founder of Skin & Aesthetic Surgery of Manhattan, said. 'The products themselves don't contain salmon sperm; they contain fragments that are derived from salmon sperm.' Salmon PDRN has become increasingly popular, particularly in South Korea and parts of Europe, for a couple reasons. 'The DNA extracted is surprisingly rich in protein and nucleic acid,' Dr. Ellen Marmur, board-certified dermatologist and founder of MMSkincare, said. 'These ingredients hold rejuvenating qualities that are perfect for an anti-aging effect.' According to Dr. Dendy Engelman, a board-certified cosmetic dermatologist and Mohs surgeon at the Shafer Clinic, this extracted DNA also closely resembles human DNA, making it effective and well tolerated in skin care products. Benefits include the stimulation of skin regeneration, hydration and collagen production. In-office salmon sperm treatments, such as the buzzy and provocative 'salmon sperm facial,' have a star-studded clientele, with high-profile fans that include Kim Kardashian and Jennifer Aniston. 'Treatments often combine microneedling or lasers with PDRN to drive the ingredient deeper, leading to firmer, healthier, more luminous skin,' Engelman said. The best part is that incorporating salmon PDRN products into your at-home routine won't have to feel like you're ingesting it on an episode of 'Fear Factor' since they can be used topically too. These products, which include everything from sheet masks to serums, combine PDRN with other popular skin care ingredients to target a range of skin concerns from home and without the high price tag associated with in-office treatments. 'Salmon PDRN is used for its ability to stimulate collagen production, accelerate the healing of open skin, deeply hydrate and reduce inflammation,' Engelman said. 'It helps repair the skin barrier, improve elasticity and can even soften fine lines and texture over time.' According to Olga Skydan, a licensed aesthetician with a medical degree in dermatology in Ukraine and medical expert board member at Luvly, many dermatologists use it in an injectable form for post-acne scarring or dull skin, and even after lasering for its anti-inflammatory effect, Henry added. Topical products with salmon PDRN aim to mimic these effects and benefits over time, and they're particularly useful for people who are dealing with sun damage, early signs of aging or compromised skin barriers, Skydan said. 'Because it's highly biocompatible, it integrates well into our skin's natural repair processes, making it a powerful tool for overall rejuvenation,' Engelman said. Rejuran Advanced Anti-Aging Retinol + c-PDRN Serum The most well-known brand when it comes to PDRN products, Rejuran's anti-aging serum is a favorite amongst our experts. 'I'm particularly impressed by this product, which combines salmon DNA with stabilized vitamin C and retinol to target fine lines, texture and pigmentation,' Engelman said. Both she and Marmur recommend it for those in search of a comprehensive anti-aging approach. Medicube PDRN Pink Collagen Exosome Shot For those just dipping their toes into the world of PDRN skin care, both Henry and Marmur recommend this under-$25 spicule serum that enhances your skin care's absorption. It's available in two different parts per million (PPM) formulas of varying concentrations, both of which target a range of skin care concerns, from boosting elasticity to smoothing textured or rough skin to boosting hydration, Henry said. If you have sensitive skin, be sure to start with the gentler option. VT Cosmetics PDRN 100 Essence 'You can get PDRN from salmon, but there are other plant-based sources being studied like rose or ginkgo,' Henry said. This lightweight yet nourishing essence boasts PDRN derived from ginseng, which the brand claims to be more stable and have a lower molecular weight than its animal-derived counterpart. The vegan PDRN alternative also includes a nourishing ceramide complex and soothing panthenol. Genabelle PDRN Vita Toning Ampoule Skydan describes this ampoule — a term generally used to describe highly concentrated and targeted liquid skin care products — as a solid introduction to PDRN skin care. 'It blends salmon DNA with niacinamide and vitamins to brighten, hydrate and improve texture,' she said, adding that it's a great option 'for people dealing with dull or uneven skin and want that 'glass skin' finish without irritating ingredients.' She recommends applying two to three drops of the product after cleansing but before your moisturizer, both in the morning and at night. Abib PDRN Retinal Eye Patch Beauty and fashion editor Sophie Shaw recently added these anti-aging under-eye patches into her routine. They're saturated in a vegan PDRN serum that's derived from cica, ginkgo and bamboo, and the formula also contains caffeine, niacinamide and retinal to help reduce puffiness and fine lines. Gangnam Glow Rejunol Mucin PDRN Facial Cream Salmon PDRN and snail mucin, two K-beauty staples, meet in this face moisturizer. While PDRN is commonly touted for its anti-aging benefits, it's also an effective way to keep your skin hydrated, according to Marmur. 'The DNA strands have a rich network of hydrogen bonds capable of carrying water,' she said, providing deep hydration to your skin for that plump and healthy look. A nourishing cream, such as this option, is also an easy way to maximize your overnight skin care routine. Derma Factory PDRN 4% Ampoule 'This is one of the strongest over-the-counter PDRN products on the market, with a 4% concentration,' Skydan said. 'It's best for people dealing with compromised skin barriers, post-acne inflammation or irritation after treatments like microneedling.' She recommends applying it at night on clean skin and following it up with a gentle moisturizer. 'If your skin is sensitive, start with twice a week and then build up,' she said, adding that it's best to keep it in a cool, dark place to preserve the formula's stability. Centellian 24 360° Shot PDRN Active Serum Shaw also likes this PDRN serum that leaves her skin plump and hydrated. It contains collagen, ginseng root, turmeric and niacinamide to fortify the skin. She likes to use her Medicube Mini Booster Pro to smooth the gel formula over her skin and ensure maximum absorption. Innisfree Retinol Green Tea PDRN Firming and Smoothing Serum Looking for a vegan product? According to Marmur, vegan alternatives to salmon PDRN are worth exploring for their similarly excellent results. One example is this green tea-derived PDRN, which is extracted from patented lactic acid bacteria from green tea. The cruelty-free formulation also includes retinol to help firm skin and smooth the appearance of fine lines. Medicube Salmon PDRN Pink Collagen Jelly Gel Mask Engelman recommends this jelly-textured face mask, which is designed to be left on the skin for about three to four hours. Once your skin has completely absorbed the mask, you'll notice it will transform from opaque to transparent. 'It contains salmon PDRN, hydrolyzed collagen, peptides and niacinamides to hydrate, brighten and plump the skin,' she said. Valmont V-Lift Neck Cream If you're looking for an anti-aging product to target both your neck and face, Marmur recommends this luxury cream from Valmont, a brand that incorporates highly polymerized salmon roe DNA into its V-Lift collection. 'I like this specifically because it's made for your neck, which tends to age faster than the skin on our faces,' she said. 'It absorbs easily and gives quick results.' Genabelle PDRN 3% Hyper Boost Ampoule Ideal for those looking to restore a dewy and resilient complexion, Engelman recommends this 'beautifully formulated intensive treatment that leverages high-concentration PDRN' for improving skin elasticity and hydration. 'It works best incorporated into an evening regimen,' she said, advising clients with sensitive skin to introduce it into their routine gradually to minimize irritation. The following FAQs have been answered by dermatologists Dr. Dendy Engelman, Dr. Michelle Henry, Dr. Ellen Marmur and Olga Skydan. Is salmon sperm good for skin? Is salmon sperm good for skin? 'Salmon sperm supports tissue repair, boosts elasticity and helps calm redness,' Engelman said. 'Many patients notice smoother, stronger, more resilient skin after consistent use.' Skydan calls it a game changer. 'It's gentle, doesn't over-exfoliate or sensitize the skin and suits a range of skin types,' she said. 'But it works best as part of a consistent routine rather than a miracle one-off.' Like most skin care products, consistency is key. Skydan said to think of adding PDRN into your skin care routine as a long-term investment in your skin's recovery and strength as opposed to a quick or instant fix. Salmon PDRN's benefits are said to extend beyond the aesthetic. Marmur notes it has potential to aid in wound healing and overall anti-inflammatory effects, though more research and larger-scale studies are needed. 'There is anecdotal evidence that is very promising,' she said, sharing that she uses salmon PDRN topically on many of her patients after in-office procedures, and they do see good results. 'However, we can't compare these results to what our colleagues are seeing in Europe or Asia, where PDRN is approved for injection and is very popular,' she said. 'In the US, we're still waiting for the pool of data to grow so we can fully understand its full potential and its long-term safety profile.' Are salmon sperm facials FDA approved? Are salmon sperm facials FDA approved? 'No, salmon sperm facials — specifically the injectable forms using PDRN — are not FDA approved in the US at this time,' Engelman said. 'While topical creams or serums with salmon DNA are permitted under cosmetic guidelines, injectable versions still lack formal FDA clearance,' she said. In short, 'anyone considering these treatments should proceed cautiously and always seek trusted, well-trained providers using products that comply with US regulations,' Engelman said. What are the side effects of a salmon sperm facial? What are the side effects of a salmon sperm facial? 'Potential side effects of a salmon sperm (PDRN) facial include temporary redness, swelling, bruising or mild irritation, especially if paired with microneedling or injections,' Engelman said. 'Some people may also notice slight peeling or increased sensitivity as the skin renews.' If you're opting for a topical salmon sperm facial, 'side effects are rare but could include irritation if the formula includes other active ingredients or if your skin is sensitive,' Skydan said. For those allergic to fish, our experts generally advise against salmon-derived PDRN products or facials. 'Because PDRN is derived from salmon, there's a theoretical risk of a reaction if you have a fish allergy,' Engelman said. 'While the DNA is highly purified, we still advise caution. Anyone with a known fish allergy should generally avoid these treatments or discuss them thoroughly with their dermatologist first to minimize any risk.' For this article, we consulted the following skin experts to gain their professional insights. Dr. Dendy Engelman, board-certified cosmetic dermatologist and Mohs surgeon at Shafer Clinic in New York Dr. Michelle Henry, board-certified dermatologist and founder of Skin & Aesthetic Surgery of Manhattan Dr. Ellen Marmur, board-certified dermatologist and founder of MMSkincare Olga Skydan, licensed aesthetician with a medical degree in dermatology in Ukraine and medical expert board member at Luvly CNN Underscored has a team of skilled writers and editors who have many years of experience testing, researching and recommending products, and they ensure each article is carefully edited and products are properly vetted. We talk to top experts when applicable to make certain we are testing each product accurately, recommending only the best products and considering the pros and cons of each item. For this story, contributing writer Noelle Ike spoke to dermatologists about salmon PDRN, or 'salmon sperm' skin care, and its benefits.
Daily Mail
15-07-2025
- Entertainment
- Daily Mail
Leslie Ash, 65, shows off her youthful face as she opens about doing £4,500 'facelift' that 'made her look ten years younger'
Leslie Ash has opened up about doing a £4,500 non-surgical facelift that made her look 'ten years younger'. The beloved BBC star, 65, showed off the jaw-dropping results of the revolutionary method, which she has been secretly doing for the past eight months. 'My friends think I've had a facelift - but I've definitely not gone under the knife,' the Holby City favourite told candidly as she praised the avant-garde NeoGen treatment. Leslie admitted to being a bit of a 'wuss' when it comes to pain but said the NeoGen treatments were bearable - in a move which comes 23 years after she famously underwent botched lip fillers and inspired the term 'Trout Pout'. On the new treatment, she said: 'It's quite a weird sensation, I was lathered in numbing cream for half an hour before having the treatment. It's non-invasive but you can feel it, you can put up with it though. 'You might be a bit red for a day or two afterwards, like you've had a bit too much sun, but after that it's just amazing, your skin just feels so much tighter and you start to notice your pores closing,' she finished. As she looked at some before and after treatment pictures, she was quick to point out: 'The difference is really noticeable, and what's really blown my mind is my jawline, it's so obvious that it has lifted. 'Also, my eyes look so much better, they were hooded before and now you can see my eyes are completely a different shape. 'Then you come to the texture of my skin, and reduction of my pores, now it looks soft as anything and the colour is uniform, so there are four major things that are demonstrably improved.' The Happy Apple icon was aiming for a natural result rather than resorting to plastic surgery in order to maintain her natural beauty. 'It doesn't look fake or overdone at all. It's just me, but a much better version of me,' Leslie told. 'My skin feels tighter and more plump, and the overall texture and tone is so much better. The actress added proudly: 'I can definitely say I look like I'm in my mid 50s, so yeah, I'm happy with that, ten years younger.' 'Also, my eyes look so much better, they were hooded before and now you can see my eyes are completely a different shape. Then you come to the texture of my skin, and reduction of my pores,' she said Leslie, also accompanied her treatment with a regular aid of supplements Ameri-Vita. 'I'm absolutely going to keep having these treatments,' she assured. 'The results are so good, I can't imagine stopping now.' NeoGen Plasma treatments are available at Dr Martin Kinsella's Re-Enhance clinic in Hale, Cheshire, and also in London. The British star appeared over the moon - after recently opening up about the 2004 incident that changed her life.
The Sun
15-07-2025
- Entertainment
- The Sun
Leslie Ash, 65, reveals the results of her £4,500 non-surgical facelift saying ‘I look ten years younger'
MEN Behaving Badly actress Leslie Ash has undergone a non-surgical facelift. The star, 65, revealed the results of the £4,500 treatment, admitting: 'My friends think I've had a facelift.' 5 5 But Leslie hasn't gone under the knife and instead has been secretly having non-surgical facelift treatments. Over the past eight months, Leslie has had six procedures, known as 'NeoGen Plasma Treatment' with Dr Martin Kinsella. She said: "People keep saying to me, 'What have you done? You look amazing!' "One friend of mine, who shall remain nameless, is convinced I've had surgery because the change was so dramatic, but I can assure you I haven't. "It was really important for me to have a non-invasive treatment that achieves really natural looking results." The actress added: "I'd seen that Shirley Ballas and Linda Lusardi had great results with NeoGen and I know Linda, so it was easy for me to check it out and know that it was a respected treatment with good outcomes." Leslie decided to book in for a consultation after struggling with her visible signs of ageing for a while, which were significantly impacting her self-esteem. 'The difference is really noticeable,' Leslie said after her treatments. 'What's really blown my mind is my jawline, it's so obvious that it has lifted. "And my eyes look so much better, they were hooded before and now you can see my eyes are a completely different shape.' Leslie Ash says horror hospital superbug destroyed her TV career and left her walking with a stick on Good Morning Britain interview She continued: 'Then you come to the texture of my skin, and the reduction of my pores. "My skin feels tighter and more plump, and the overall texture and tone is so much better. "I can definitely say I look like I'm in my mid 50s, so yeah, I'm happy with that, ten years younger.' NeoGen Plasma Treatment works by using ultra-high radio frequency to convert nitrogen gas into nitrogen plasma. A handpiece directs this thermal plasma into the layers of the skin to help control its pre-existing plasma, boosting the skin's natural regenerative mechanism. It's essentially tricking the skin into boosting its levels of collagen and elastin - the two main building blocks of healthy, supple skin. Leslie, who has also been taking daily Ameri-Vita Liver Support drinks, has no plan to call it quits now she's found a treatment that works wonders for her. 'I'm absolutely going to keep having these treatments," she said. "I can't imagine stopping now.' 5
Associated Press
05-07-2025
- Health
- Associated Press
CELFULL Unveils Celfavor NADH Microcapsules: A Breakthrough in Stability That Reshapes the Anti-Aging Industry
CORAL SPRINGS, FL / ACCESS Newswire / July 4, 2025 / CELFULL, a biotechnology company with over 25 years of expertise in anti-aging science, has announced a major breakthrough in longevity innovation: the global launch of Celfavor® NADH Microcapsules, a patented delivery system that resolves the century-long challenge of NADH instability. Journal papers related to NADH This revolutionary technology-protected by seven international invention patents across the U.S., China, Japan, Canada, and South Korea-delivers unprecedented improvements in stability, bioavailability, and targeted delivery, marking a new era in anti-aging therapeutics known as the 'Microcapsule Age.' To accelerate research across the globe, CELFULL has also launched its Global Research Sharing Program, offering free access to the Celfavor® NADH raw material to scientific institutions worldwide. Celfavor®NADH The only effective NADH - Celfavor ® NADH 'The discovery of the therapeutic effect of stabilized NADH is more important to humankind than the discovery of antibiotics.' noted Nobel Laureate Sir John Eccles, underscoring the importance of this innovation. NADH stands for 'nicotinamide adenine dinucleotide (NAD) + hydrogen (H), often dubbed the 'King of Anti-Aging Molecules,' plays a central role in mitochondrial energy production, antioxidant defense, and the activation of longevity proteins. However, its inherent instability-sensitive to heat, light, oxygen, and stomach acid-has severely limited its clinical applications. Conventional NADH degrades by over 70% in one month at room temperature and must be stored at -20°C, making practical use difficult. 7 patents have been certified CELFULL's research team, led by its AI-powered Multi-Target Anti-Aging Institute, spent over a decade solving this problem. The result: Celfavor® NADH Microcapsules, a proprietary technology featuring 250-350μm microcapsules that protect NADH with a multi-core soluble shell made from food-grade materials. In stability tests simulating harsh conditions (40°C / 75% RH), traditional NADH retained only 3.5% of its activity after six months. By contrast, Celfavor® NADH maintained 98.3% activity-demonstrating over 6x shelf-life extension, even without refrigeration or light shielding. The stability of Celfavor® NADH microspheres The Celfavor® NADH Microcapsule system delivers innovation across four dimensions: 1. Enhanced Stability: Microcapsules shield NADH from air, moisture, light, and stomach acid, preserving its full potency in gastrointestinal conditions for up to 4 hours. 2. Targeted Release: Using AI-optimized wall material, the system enables 'zero release in the stomach and sustained release in the intestine.' Simulated intestinal studies show 24-hour continuous release, extending absorption time by 5-8x. 3. Superior Bioavailability: In human trials, a daily dose of 40mg led to a 98% increase in blood NAD⁺ levels, a 3.2x improvement over regular NADH. Performance also surpassed other NAD⁺ precursors like NMN and NR. 4. Formulation Flexibility: Unlike unstable NADH, Celfavor® NADH can be safely co-formulated with vitamins, coenzymes, or peptides in single or multi-ingredient capsules. Celfavor ® NADH microsphere advanced technology surpasses others Celfavor® NADH Microcapsules have been granted seven invention patents and passed all 12 safety evaluations, including cytotoxicity and long-term toxicity tests. It is currently the only NADH raw material globally to pass full-spectrum safety certification. The only globally certified raw material for toxicology and safety experiments 'We are not just creating better products-we are building a platform for the future of longevity,' said Dr. Juliane Hitzel, CEO of CELFULL. 'With this microcapsule technology, we're launching new delivery systems for vitamins, peptides, and more. And by sharing our raw materials with global researchers, we're fostering a collaborative ecosystem that accelerates anti-aging science.' From solving the NADH stability problem to advancing intelligent delivery systems, CELFULL's innovation signals a major milestone in human longevity science. As the Celfavor® NADH Microcapsule technology rolls out globally, the anti-aging industry enters a new chapter-one defined by precision, efficiency, and collaboration. For business cooperation or research partnerships, please contact: [email protected] | Email: [email protected] Website: SOURCE: CELFULL press release
Yahoo
05-07-2025
- Health
- Yahoo
CELFULL Unveils Celfavor NADH Microcapsules: A Breakthrough in Stability That Reshapes the Anti-Aging Industry
CORAL SPRINGS, FL / / July 4, 2025 / CELFULL, a biotechnology company with over 25 years of expertise in anti-aging science, has announced a major breakthrough in longevity innovation: the global launch of Celfavor® NADH Microcapsules, a patented delivery system that resolves the century-long challenge of NADH instability. Journal papers related to NADH This revolutionary technology-protected by seven international invention patents across the U.S., China, Japan, Canada, and South Korea-delivers unprecedented improvements in stability, bioavailability, and targeted delivery, marking a new era in anti-aging therapeutics known as the "Microcapsule Age." To accelerate research across the globe, CELFULL has also launched its Global Research Sharing Program, offering free access to the Celfavor® NADH raw material to scientific institutions worldwide. Celfavor®NADH The only effective NADH - Celfavor ® NADH "The discovery of the therapeutic effect of stabilized NADH is more important to humankind than the discovery of antibiotics." noted Nobel Laureate Sir John Eccles, underscoring the importance of this innovation. NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H), often dubbed the "King of Anti-Aging Molecules," plays a central role in mitochondrial energy production, antioxidant defense, and the activation of longevity proteins. However, its inherent instability-sensitive to heat, light, oxygen, and stomach acid-has severely limited its clinical applications. Conventional NADH degrades by over 70% in one month at room temperature and must be stored at -20°C, making practical use difficult. 7 patents have been certified CELFULL's research team, led by its AI-powered Multi-Target Anti-Aging Institute, spent over a decade solving this problem. The result: Celfavor® NADH Microcapsules, a proprietary technology featuring 250-350μm microcapsules that protect NADH with a multi-core soluble shell made from food-grade materials. In stability tests simulating harsh conditions (40°C / 75% RH), traditional NADH retained only 3.5% of its activity after six months. By contrast, Celfavor® NADH maintained 98.3% activity-demonstrating over 6x shelf-life extension, even without refrigeration or light shielding. The stability of Celfavor® NADH microspheres The Celfavor® NADH Microcapsule system delivers innovation across four dimensions: 1. Enhanced Stability: Microcapsules shield NADH from air, moisture, light, and stomach acid, preserving its full potency in gastrointestinal conditions for up to 4 hours. 2. Targeted Release: Using AI-optimized wall material, the system enables "zero release in the stomach and sustained release in the intestine." Simulated intestinal studies show 24-hour continuous release, extending absorption time by 5-8x. 3. Superior Bioavailability: In human trials, a daily dose of 40mg led to a 98% increase in blood NAD⁺ levels, a 3.2x improvement over regular NADH. Performance also surpassed other NAD⁺ precursors like NMN and NR. 4. Formulation Flexibility: Unlike unstable NADH, Celfavor® NADH can be safely co-formulated with vitamins, coenzymes, or peptides in single or multi-ingredient capsules. Celfavor ® NADH microsphere advanced technology surpasses others Celfavor® NADH Microcapsules have been granted seven invention patents and passed all 12 safety evaluations, including cytotoxicity and long-term toxicity tests. It is currently the only NADH raw material globally to pass full-spectrum safety certification. The only globally certified raw material for toxicology and safety experiments "We are not just creating better products-we are building a platform for the future of longevity," said Dr. Juliane Hitzel, CEO of CELFULL. "With this microcapsule technology, we're launching new delivery systems for vitamins, peptides, and more. And by sharing our raw materials with global researchers, we're fostering a collaborative ecosystem that accelerates anti-aging science." From solving the NADH stability problem to advancing intelligent delivery systems, CELFULL's innovation signals a major milestone in human longevity science. As the Celfavor® NADH Microcapsule technology rolls out globally, the anti-aging industry enters a new chapter-one defined by precision, efficiency, and collaboration. For business cooperation or research partnerships, please contact:maggie@ | Email: maggie@ SOURCE: CELFULL View the original press release on ACCESS Newswire Error while retrieving data Sign in to access your portfolio Error while retrieving data Error while retrieving data Error while retrieving data Error while retrieving data
