Latest news with #dosSantos
New Straits Times
a day ago
- Sport
- New Straits Times
Dos Santos speaks the Harimau language
KUALA LUMPUR: Before instructions get lost in translation or the ball gets lost in transition, national footballer Endrick dos Santos is doing his part in helping the disparate Harimau Malaya team get going. While local TV commentators are still trying to get used to remembering or pronouncing the plethora of foreign-sounding names, fans must be wondering about communication among players and coaches on the field. In this aspect, the Brazil-born dos Santos believes he can help members of the newly assembled Malaysia team connect and click with one another. Fluent in English, Spanish, and increasingly proficient in Bahasa Malaysia, dos Santos plays a really important role. He is the go-to translator, the cultural bridge between East and West, the unifying voice in the rojak-like national team that aim to turn incoherence into cohesion. As Malaysia face Vietnam in a crucial Asian Cup qualifier on Tuesday, the national players, cobbled from all corners of the world, are brushing up on team work, learning and understanding each other's style and rhythm. Recently, the national team announced the inclusion of five more foreign-born heritage players: Rodrigo Holgado (Argentina), Imanol Machuca (Argentina), Facundo Garces (Argentina), Jon Irazabal (Spain) and Joao Figueiredo (Brazil), The naturalised dos Santos, who has donned Harimau Malaya colours since 2023. said: "It's a little difficult for them to communicate, but the others and I speak a little English, Spanish, and Malay. So, we try to help each other, to pass on to them whatever is important. "We try to communicate during every training session. I try to help my teammates adapt faster." But ultimately, fans around the world like to speak only one language — the language of winning.
Global News
27-05-2025
- Health
- Global News
Canadian-made test could help diagnose sepsis, researchers say
A team of Canadian researchers has created a test they say could quickly predict if a patient is going to develop sepsis, a life-threatening condition that happens when the immune system has a dysfunctional reaction to an infection and starts attacking the body's own organs and tissues. Sepsis kills thousands of people in Canada and close to 50 million people worldwide every year, said Dr. Claudia dos Santos, senior author of a research paper about the test published Tuesday in the journal Nature Communications. Treating sepsis quickly is crucial to survival, said dos Santos, who is a clinician-scientist and critical care physician at St. Michael's Hospital in Toronto. 'A one-hour delay in the treatment of sepsis can increase mortality by close to eight per cent,' she said, noting that acting within the first six hours is very important. Story continues below advertisement The problem is that there is currently no single test that can tell doctors which patients with infections — which can be anything from COVID-19 to a bacterial infection from a cut — will go on to develop sepsis, she said. That's because symptoms of sepsis are 'non-specific' and could also be symptoms of illness from the infection itself, including a fever, a high respiratory or heart rate, low blood pressure, low urine output, an abnormal white blood cell count and confusion. 2:11 Raising awareness of the world's #1 killer So physicians use their best clinical judgment, but it's based on a 'suspicion' of sepsis rather than a clear biological marker, dos Santos said. Get weekly health news Receive the latest medical news and health information delivered to you every Sunday. Sign up for weekly health newsletter Sign Up By providing your email address, you have read and agree to Global News' Terms and Conditions and Privacy Policy 'We do everything that we possibly can in the first six golden hours of sepsis and we cross our fingers and watch and see what happens. And the motivation behind this paper is there has to be a better way.' Story continues below advertisement Dos Santos and colleagues from the University of British Columbia and National Research Council Canada believe they've found it — a blood test that could predict a patient's likelihood of developing sepsis. Robert Hancock, director of UBC's centre for microbial diseases and immunity research, led a team that used artificial intelligence to find genes that stood out in patients who went on to develop sepsis — and found six that they called 'Sepset.' 'The idea is that in sepsis, each of these six genes is more highly expressed than it is when the patients aren't in sepsis,' said Hancock. 'Really critically, we see this phenomenon occurring before there is an obvious diagnosis of sepsis.' The researchers examined blood samples from 586 past patients and found higher levels of those six genes when patients' immune systems were starting to react abnormally. They found that when there was an increased presence of those genes, the patients went into sepsis within 24 hours. Testing patients to see if they have that six-gene 'signature' could allow physicians to take immediate action to treat sepsis early, including starting antibiotics if a bacterial infection is suspected, increasing fluids to help keep blood pressure stable and preparing to move the patient to intensive care if they need respiratory support or other critical care measures, dos Santos said. Story continues below advertisement Those actions can all happen while doctors pinpoint the initial infection and treat it with antibiotics, steroids, or other medications. 1:41 IWK health centre introducing new screening tool for sepsis in children The researchers also wanted to make the sepsis test portable, so it could be brought to a patient's bedside in the emergency department or used in remote communities to decide whether a patient needs to be transported to an urban hospital. National Research Council Canada developed a small device that takes less than 50 microlitres of blood — one or two drops — and extracts RNA to detect how much of the six signature genes are present. The device — called Powerblade — produced the results in less than three hours. When tested using 30 of the blood samples from previous patients, it was 92 per cent accurate in predicting who had developed sepsis, the researchers say. Story continues below advertisement An important limitation of the study is that the test has not yet been used with patients in real time, the paper says. Dos Santos said that's the next step, in the form of a clinical trial funded by the Canadian Institutes of Health Research. She's hoping they'll be able to start it this year. 'We're actually going to test the device, the prototype, in the real-world environment and demonstrate that we can do the whole thing for real,' she said. 'And then we need to find out, once we have those results, how does that change (patient) outcomes?'
Hamilton Spectator
27-05-2025
- Health
- Hamilton Spectator
Canadian researchers develop test they say can help diagnose life-threatening sepsis
TORONTO - A team of Canadian researchers has created a test they say could quickly predict if a patient is going to develop sepsis, a life-threatening condition that happens when the immune system has a dysfunctional reaction to an infection and starts attacking the body's own organs and tissues. Sepsis kills thousands of people in Canada and close to 50 million people worldwide every year, said Dr. Claudia dos Santos, senior author of a research paper about the test published Tuesday in the journal Nature Communications. Treating sepsis quickly is crucial to survival, said dos Santos, who is a clinician-scientist and critical care physician at St. Michael's Hospital in Toronto. 'A one-hour delay in the treatment of sepsis can increase mortality by close to eight per cent,' she said, noting that acting within the first six hours is very important. The problem is that there is currently no single test that can tell doctors which patients with infections — which can be anything from COVID-19 to a bacterial infection from a cut — will go on to develop sepsis, she said. That's because symptoms of sepsis are 'non-specific' and could also be symptoms of illness from the infection itself, including a fever, a high respiratory or heart rate, low blood pressure, low urine output, an abnormal white blood cell count and confusion. So physicians use their best clinical judgment, but it's based on a 'suspicion' of sepsis rather than a clear biological marker, dos Santos said. 'We do everything that we possibly can in the first six golden hours of sepsis and we cross our fingers and watch and see what happens. And the motivation behind this paper is there has to be a better way.' Dos Santos and colleagues from the University of British Columbia and National Research Council Canada believe they've found it — a blood test that could predict a patient's likelihood of developing sepsis. Robert Hancock, director of UBC's centre for microbial diseases and immunity research, led a team that used artificial intelligence to find genes that stood out in patients who went on to develop sepsis — and found six that they called 'Sepset.' 'The idea is that in sepsis, each of these six genes is more highly expressed than it is when the patients aren't in sepsis,' said Hancock. 'Really critically, we see this phenomenon occurring before there is an obvious diagnosis of sepsis.' The researchers examined blood samples from 586 past patients and found higher levels of those six genes when patients' immune systems were starting to react abnormally. They found that when there was an increased presence of those genes, the patients went into sepsis within 24 hours. Testing patients to see if they have that six-gene 'signature' could allow physicians to take immediate action to treat sepsis early, including starting antibiotics if a bacterial infection is suspected, increasing fluids to help keep blood pressure stable and preparing to move the patient to intensive care if they need respiratory support or other critical care measures, dos Santos said. Those actions can all happen while doctors pinpoint the initial infection and treat it with antibiotics, steroids, or other medications. The researchers also wanted to make the sepsis test portable, so it could be brought to a patient's bedside in the emergency department or used in remote communities to decide whether a patient needs to be transported to an urban hospital. National Research Council Canada developed a small device that takes less than 50 microlitres of blood — one or two drops — and extracts RNA to detect how much of the six signature genes are present. The device — called Powerblade — produced the results in less than three hours. When tested using 30 of the blood samples from previous patients, it was 92 per cent accurate in predicting who had developed sepsis, the researchers say. An important limitation of the study is that the test has not yet been used with patients in real time, the paper says. Dos Santos said that's the next step, in the form of a clinical trial funded by the Canadian Institutes of Health Research. She's hoping they'll be able to start it this year. 'We're actually going to test the device, the prototype, in the real-world environment and demonstrate that we can do the whole thing for real,' she said. 'And then we need to find out, once we have those results, how does that change (patient) outcomes?' This report by The Canadian Press was first published May 27, 2025. Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.
Winnipeg Free Press
27-05-2025
- Health
- Winnipeg Free Press
Canadian researchers develop test they say can help diagnose life-threatening sepsis
TORONTO – A team of Canadian researchers has created a test they say could quickly predict if a patient is going to develop sepsis, a life-threatening condition that happens when the immune system has a dysfunctional reaction to an infection and starts attacking the body's own organs and tissues. Sepsis kills thousands of people in Canada and close to 50 million people worldwide every year, said Dr. Claudia dos Santos, senior author of a research paper about the test published Tuesday in the journal Nature Communications. Treating sepsis quickly is crucial to survival, said dos Santos, who is a clinician-scientist and critical care physician at St. Michael's Hospital in Toronto. 'A one-hour delay in the treatment of sepsis can increase mortality by close to eight per cent,' she said, noting that acting within the first six hours is very important. The problem is that there is currently no single test that can tell doctors which patients with infections — which can be anything from COVID-19 to a bacterial infection from a cut — will go on to develop sepsis, she said. That's because symptoms of sepsis are 'non-specific' and could also be symptoms of illness from the infection itself, including a fever, a high respiratory or heart rate, low blood pressure, low urine output, an abnormal white blood cell count and confusion. So physicians use their best clinical judgment, but it's based on a 'suspicion' of sepsis rather than a clear biological marker, dos Santos said. 'We do everything that we possibly can in the first six golden hours of sepsis and we cross our fingers and watch and see what happens. And the motivation behind this paper is there has to be a better way.' Dos Santos and colleagues from the University of British Columbia and National Research Council Canada believe they've found it — a blood test that could predict a patient's likelihood of developing sepsis. Robert Hancock, director of UBC's centre for microbial diseases and immunity research, led a team that used artificial intelligence to find genes that stood out in patients who went on to develop sepsis — and found six that they called 'Sepset.' 'The idea is that in sepsis, each of these six genes is more highly expressed than it is when the patients aren't in sepsis,' said Hancock. 'Really critically, we see this phenomenon occurring before there is an obvious diagnosis of sepsis.' The researchers examined blood samples from 586 past patients and found higher levels of those six genes when patients' immune systems were starting to react abnormally. They found that when there was an increased presence of those genes, the patients went into sepsis within 24 hours. Testing patients to see if they have that six-gene 'signature' could allow physicians to take immediate action to treat sepsis early, including starting antibiotics if a bacterial infection is suspected, increasing fluids to help keep blood pressure stable and preparing to move the patient to intensive care if they need respiratory support or other critical care measures, dos Santos said. Those actions can all happen while doctors pinpoint the initial infection and treat it with antibiotics, steroids, or other medications. The researchers also wanted to make the sepsis test portable, so it could be brought to a patient's bedside in the emergency department or used in remote communities to decide whether a patient needs to be transported to an urban hospital. National Research Council Canada developed a small device that takes less than 50 microlitres of blood — one or two drops — and extracts RNA to detect how much of the six signature genes are present. The device — called Powerblade — produced the results in less than three hours. When tested using 30 of the blood samples from previous patients, it was 92 per cent accurate in predicting who had developed sepsis, the researchers say. An important limitation of the study is that the test has not yet been used with patients in real time, the paper says. Wednesdays A weekly look towards a post-pandemic future. Dos Santos said that's the next step, in the form of a clinical trial funded by the Canadian Institutes of Health Research. She's hoping they'll be able to start it this year. 'We're actually going to test the device, the prototype, in the real-world environment and demonstrate that we can do the whole thing for real,' she said. 'And then we need to find out, once we have those results, how does that change (patient) outcomes?' This report by The Canadian Press was first published May 27, 2025. Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.
Yahoo
17-05-2025
- Sport
- Yahoo
Karen Weekly on Tennessee softball's offense vs Miami (Ohio) in NCAA regional opener
dos Santos dominates 400m hurdles in Miami After winning the 400m hurdles at the Grand Slam Track event in Kingston, Jamaica, Alison dos Santos secured a second-straight win in the same event in Miami by capitalizing on a mistake-ridden field. 5:16 Now Playing Paused Ad Playing
