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The 'health' food loved by the wealthiest Americans now linked to Lou Gehrig's disease
The 'health' food loved by the wealthiest Americans now linked to Lou Gehrig's disease

Daily Mail​

time4 days ago

  • Health
  • Daily Mail​

The 'health' food loved by the wealthiest Americans now linked to Lou Gehrig's disease

The toxic cousin of a gourmet delicacy could put foodies at risk of a devastating and irreversible neurological disorder. A true morel is one of the most luxurious and sought-after wild mushrooms, often featured in high-end cuisine from risotto to a cream sauce over steak due to its earthy, nutty flavor and exclusive seasonal availability. Morels are coveted in the culinary world, but they have deceptive, poisonous lookalikes. False morels have tricked amateur foragers and garnered true fans in a town called Montchavin, a village in the French Alps, for their 'rejuvenating' properties. Despite their name, though, they belong to an entirely different family of fungi, the Gyromitra. False morels contain compounds called hydrazines that are toxic to the nervous system. While eating one may cause abdominal pain and diarrhea, in severe cases, a false morel can cause seizures and multi-organ failure. Gyromitrin, the main toxin in the mushroom, is also a carcinogen. Recently, scientists believe they've found a link between false morels and Amyotrophic Lateral Sclerosis (ALS) in Montchavin, as a mysterious cluster of cases has developed over the last decade. Also known as Lou Gehrig's disease, ALS is a fatal neurological disorder that progressively paralyzes patients. Montchavin has a permanent population of about 200 people, and the average global diagnosis rate of ALS is two to three diagnoses per 100,000 people annually. Yet in the last decade, there have been 16 cases reported in Montchavin, far more than what would be expected. If made comparable to a rate in 100,000 people per year, Montchavin's rate would be 800 cases per 100,000 residents per year. The search for answers was led by Dr Emmeline Lagrange, a neurologist practicing at Grenoble University Hospital, 84 miles southwest of the village. A resident of Montchavin who had been experiencing neurological issues had been referred to Lagrange, who diagnosed them with ALS. She would later learn on a call with the patient's referring physician in Montchavin that this was one of several ALS cases in the small mountain village. None of the patients had a gene mutation making them more susceptible to ALS or a family history of the disease, which causes continuously worsening paralysis over time, leading to death after two to five years. Scientists are still investigating the cause of ALS, which affects roughly 33,000 Americans. Genetics are behind between 10 and 15 percent of cases, while the rest could be tied to environmental exposures, including toxic pollution, smoking, exposure to heavy metals like lead and mercury, and a history of head injuries. Lagrange published an abstract summarizing her investigation into the unusual ALS cluster, which caught the eye of environmental neuroscientist Dr Peter Spencer of the Oregon Health & Science University in Portland. Spencer is the leading proponent of a separate theory linking food to the degenerative disease. His theory was that toxins in cycad seeds, once a staple of Guam's Chamorro people, triggered an epidemic of Western Pacific ALS-Parkinsonism dementia (ALS-PDC). At its peak, ALS-PDC was 50 to 100 times more common in Guam than ALS rates worldwide. In the 1950s, incidence rates reached about 200 per 100,000 among Chamorro adults. He has investigated the link for over four decades, arguing that a compound in cycad seeds called cycasin metabolizes into a neurotoxic DNA-damaging byproduct called methylazoxymethanol (MAM). MAM is also formed when the body metabolizes hydrazine, a volatile chemical used in rocket fuels and also found in false morels. When Spencer saw a presentation of Lagrange's abstract, his mind lingered on one line. He told Knowable Magazine: 'I noted that among the foodstuffs they reported were mushrooms. 'And I asked them what type of mushrooms, because one particular type contains poisons associated with the Guam problem.' They began collaborating on a study. Lagrange had learned that the ALS patients in Montchavin had been purposely seeking out false morels, believing they had rejuvenating properties, despite their illegal status. A villager told Lagrange: 'They are always in a group, a secret group, a social network, and they eat the mushrooms. And they all knew that it's forbidden.' The researchers included those patients in their study, as well as 48 villagers without the disease who ate wild mushrooms, but not false morels. Some ALS patients had a history of collecting up to six pounds of the poisonous fungi during the spring and summer and eating them throughout the year. People who had been diagnosed with ALS had been eating the mushrooms for as long as 20 years before ALS symptoms arose. 'All ALS cases but none of the controls had a history of consuming acutely poisonous False Morels, notably the Snow Morel Gyromitra gigas,' Lagrange concluded. 'Since no other significant chemical or physical exposure was found, the primary risk factor for ALS in this community appears to be repeated ingestion of these neurotoxic fungi.' Despite the false morel's toxicity, it is a delicacy in parts of Scandinavia, where Michelin-starred restaurants incorporate it on seasonal menus for its tang and nuttiness. The Finns are such big fans that the species was featured on a 1974 postage stamp. False morels are also endorsed by the Finnish Food Authority, which advises people to repeatedly boil and rinse fresh or dried specimens before eating. Despite their differences in appearance, amateur foragers often confuse true morels with false ones, which resemble a reddish brain. A June 2024 Toxicon study identified 118 false morel poisonings in Michigan between 2002 and 2020. Most of the patients suffered from vomiting, diarrhea, and abdominal pain, while over a dozen developed liver damage. One sustained a kidney injury, and others reported neurological effects such as headaches and dizziness.

Urgent beach warning as two Brits poisoned on UK island & rushed to A&E after eating dangerous plant with NO antidote
Urgent beach warning as two Brits poisoned on UK island & rushed to A&E after eating dangerous plant with NO antidote

The Sun

time13-05-2025

  • Health
  • The Sun

Urgent beach warning as two Brits poisoned on UK island & rushed to A&E after eating dangerous plant with NO antidote

AN URGENT beach warning has been issued after two Brits were poisoned on a UK island and rushed to hospital. The pair has eaten a plant that contained a poison with no antidote available. 3 3 3 Emergency services rushed an island off the coast of Wales on May 3 after reports of a couple who had been poisoned. The Brits, who were on Sully Island off the Vale of Glamorgan, were thought to have ingested Hemlock - a highly poisonous plant. Sully Island is a small, uninhabited island near Barry and is about 450 metres long. The island is a designated Site of Special Scientific Interest, home to plenty of diverse and rare plants. It offers stunning views of the Welsh coastline and no permanent population, which meant rescue had to come from elsewhere. The RNLI's inshore lifeboats (ILBs) were deployed from Barry Dock to the eastern side of the tidal island. The rescue charity said: "Barry Dock RNLI's inshore lifeboat was tasked by HM Coastguard on Saturday, May 3, to locate, assess, and medevac two casualties on Sully Island reported to have potentially ingested hemlock. "The volunteer crew were advised the casualties, experienced foragers, were on the eastern beach and were located quickly. "On arrival the casualties were showing signs of anxiety so the crew immediately fitted them with lifejackets and embarked both onto the ILB for immediate transport to the mainland." Hemlock, also known as hemlock water-dropwort and hemlock root, is common in shallow water and appears like a cluster of white flowers. Urgent warning over deadly plant worse than Japanese Knotweed... do you have it near you It's often found near rivers or fresh water but can be washed up on beaches after storms. Beachgoers in Britain have been warned keep their pooches on a lead as a precautionary measure in certain spots, with four dogs having died from the plant in the Newquay, Cornwall. Thankfully for the foragers, the RNLI confirmed that after the rescue, the pair on Sully Island made a full recovery. They said: 'Once ashore they were handed to Barry coastguard rescue team (CRT) who identified elevated pulse rates. "Oxygen was prepared from the ILB's supply with an RNLI crew member staying to assist the CRT with care. 'The officer in charge remained in contact with the ambulance service while the crew monitored the casualties. "As the tide fell the ILB could not remain on scene so with their condition stable and a plan in place Barry Dock ILB stood down returned to station and was made ready for service while the casualties were taken to A&E.' SYMPTOMS OF HEMLOCK POISONING Hemlock poisoning will show symptoms after around 30 minutes, or up to 3 hours. The plant can cause a painful rash or burning on the eyes if touched. Ingesting any part of the plant can lead to poisoning which can lead to respiratory failure. Symptoms include: Trembling Burning sensation in digestive tract Increased salivation Dilated pupils Muscle pain and weakness Decreased heart rate Loss of speech Convulsions Unconsciousness If you believe you have symptoms, you should seek medical attention immediately. If possible, take a sample of the plant if it's safe do to so by using plastic gloves - or take photos. Do not try and make the infected throw up. What Are Hemlock Roots? Hemlock Roots may look like a "beautiful" flower, but they hold a deadly secret. The plant, which looks like a parsnip, could be lethal to humans and animals. Hemlock could easily kill if it was eaten as it contains fatal toxins. The toxins grow naturally and include coniine and a gamma-coniceine, which cause muscular paralysis. Anyone who ingests the harmful plant could end up with respiratory failure - which could lead to death. Only a tiny amount of Hemlock can prove fatal to a human or to livestock. It usually grows in wet, marshy places and is often confused for its non-poisonous lookalikes such as wild carrots or parsnips. If accidentally eaten, symptoms of poisoning include seizures, nausea, vomiting, abdominal pain, tremors, confusion, weakness or dizziness. The plant was previously found on a beach in Cornwall following a storm.

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