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The brain tech revolution is here — and it isn't all Black Mirror

The brain tech revolution is here — and it isn't all Black Mirror

Vox19-07-2025
is a senior editorial director at Vox overseeing the climate teams and the Unexplainable and The Gray Area podcasts. He is also the editor of Vox's Future Perfect section and writes the Good News newsletter. He worked at Time magazine for 15 years as a foreign correspondent in Asia, a climate writer, and an international editor, and he wrote a book on existential risk.
When you hear the word 'neurotechnology,' you may picture Black Mirror headsets prying open the last private place we have — our own skulls — or the cyber-samurai of William Gibson's Neuromancer. That dread is natural, but it can blind us to the real potential being realized in neurotech to address the long intractable medical challenges found in our brains. In just the past 18 months, brain tech has cleared three hurdles at once: smarter algorithms, shrunken hardware, and — most important — proof that people can feel the difference in their bodies and their moods.
A pacemaker for the brain
Keith Krehbiel has battled Parkinson's disease for nearly a quarter-century. By 2020, as Nature recently reported, the tremors were winning — until neurosurgeons slipped Medtronic's Percept device into his head. Unlike older deep-brain stimulators that carpet-bomb movement control regions in the brain with steady current, the Percept listens first. It hunts the beta-wave 'bursts' in the brain that mark a Parkinson's flare and then fires back millisecond by millisecond, an adaptive approach that mimics the way a cardiac pacemaker paces an arrhythmic heart.
In the ADAPT-PD study, patients like Krehbiel moved more smoothly, took fewer pills, and overwhelmingly preferred the adaptive mode to the regular one. Regulators on both sides of the Atlantic agreed: The system now has US and EU clearance.
Because the electrodes spark only when symptoms do, total energy use is reduced, increasing battery life and delaying the next skull-opening surgery. Better yet, because every Percept shipped since 2020 already has the sensing chip, the adaptive mode can be activated with a simple firmware push, the way you'd update your iPhone.
Waking quiet muscles
Scientists applied the same listen-then-zap logic farther down the spinal cord this year. In a Nature Medicine pilot, researchers in Pittsburgh laid two slender electrode strips over the sensory roots of the lumbar spine in three adults with spinal muscular atrophy. Gentle pulses 'reawakened' half-dormant motor neurons: Every participant walked farther, tired less, and — astonishingly — one person strode from home to the lab without resting.
Half a world away, surgeons at Nankai University threaded a 50-micron-thick 'stent-electrode' through a patient's jugular vein, fanned it against the motor cortex, and paired it with a sleeve that twitched his arm muscles. No craniotomy, no ICU — just a quick catheter procedure that let a stroke survivor lift objects and move a cursor. High-tech rehab is inching toward outpatient care.
Mental-health care on your couch
The brain isn't only wires and muscles; mood lives there, too. In March, the Food and Drug Administration tagged a visor-like headset from Pulvinar Neuro as a Breakthrough Device for major-depressive disorder. The unit drips alternating and direct currents while an onboard algorithm reads brain rhythms on the fly, and clinicians can tweak the recipe over the cloud. The technology offers a ray of hope for patients whose depression has resisted conventional treatments like drugs.
Thought cursors and synthetic voices
Cochlear implants for people with hearing loss once sounded like sci-fi; today more than 1 million people hear through them. That proof-of-scale has emboldened a new wave of brain-computer interfaces, including from Elon Musk's startup Neuralink. The company's first user, 30-year-old quadriplegic Noland Arbaugh, told Wired last year he now 'multitasks constantly' with a thought-controlled cursor, clawing back some of the independence lost to a 2016 spinal-cord injury. Neuralink isn't as far along as Musk often claims — Arbaugh's device experienced some problems, with some threads detaching from the brain — but the promise is there.
On the speech front, new systems are decoding neural signals into text on a computer screen, or even synthesized voice. In 2023 researchers from Stanford and the University of California San Francisco installed brain implants in two women who had lost the ability to speak, and managing to hit decoding times of 62 and 78 words per minute, far faster than previous brain tech interfaces. That's still much slower than the 160 words per minute of natural English speech, but more recent advances are getting closer to that rate.
Guardrails for gray matter
Yes, neurotech has a shadow. Brain signals could reveal a person's mood, maybe even a voting preference. Europe's new AI Act now treats 'neuro-biometric categorization' — technologies that can classify individuals by biometric information, including brain data — as high-risk, demanding transparency and opt-outs, while the US BRAIN Initiative 2.0 is paying for open-source toolkits so anyone can pop the hood on the algorithms.
And remember the other risk: doing nothing. Refusing a proven therapy because it feels futuristic is a little like turning down antibiotics in 1925 because a drug that came from mold seemed weird.
Twentieth-century medicine tamed the chemistry of the body; 21st-century medicine is learning to tune the electrical symphony inside the skull. When it works, neurotech acts less like a hammer than a tuning fork — nudging each section back on pitch, then stepping aside so the music can play.
Real patients are walking farther, talking faster, and, in some cases, simply feeling like themselves again. The challenge now is to keep our fears proportional to the risks — and our imaginations wide enough to see the gains already in hand.
A version of this story originally appeared in the Good News newsletter. Sign up here!
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What if your earbuds could read your mind?
What if your earbuds could read your mind?

Vox

time2 hours ago

  • Vox

What if your earbuds could read your mind?

is a senior technology correspondent at Vox and author of the User Friendly newsletter. He's spent 15 years covering the intersection of technology, culture, and politics at places like The Atlantic, Gizmodo, and Vice. The MW75 Neuro headphones are primarily used to sharpen your attention — with the new and added benefit of giving you a snapshot of your brain health. Paige Vickers/Vox; Getty Images; Neurable For the past few months, when I really needed to get something done, I put on a special pair of headphones that could read my mind. Well, kind of. The headphones are equipped with a brain-computer interface that picks up electrical signals from my brain and uses algorithms to interpret that data. When my focus starts to slip, the headphones know it, and an app tells me to take a break. It sounds like something out of science fiction, but a decade-old startup called Neurable is pioneering the technology, and it's preparing to put the brain-tracking tricks into more gadgets. Earbuds, glasses, helmets — anything that can get an electrode near your head could provide a real-time stream of data about what's going on inside of it. Neurable's technology uses a combination of electroencephalography (EEG) sensors to collect brain data and algorithms to interpret those signals. Beyond measuring attention, the company is now using that data to track and improve brain health. User Friendly A weekly dispatch to make sure tech is working for you, instead of overwhelming you. From senior technology correspondent Adam Clark Estes. Email (required) Sign Up By submitting your email, you agree to our Terms and Privacy Notice . This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. I want to emphasize again that this technology does not actually read your mind in the sense of knowing your thoughts. But, it knows when you're entertained or distracted and could one day detect symptoms of depression or, on a much more consequential front, early signs of Alzheimer's disease. I came across Neurable on a longer mission to understand the future of health-tracking technology by testing what's out there now. It's one that left me anxious, covered in smart rings and continuous glucose monitors, and more confused about the definition of well-being. That's because almost all health trackers that are popular on the market right now — Apple Watches, Oura Rings, Whoop Bands — are downstream sensors. They measure consequences, like elevated heart rate or body temperature, rather than the root cause of that state. By tapping directly into your brainwaves, a brain-computer interface can spot issues sometimes years before they would show up. It could one day detect symptoms of depression or, on a much more consequential front, early signs of Alzheimer's disease. 'Biologically, your brain is designed to hide your weaknesses: It's an evolutionary effect,' Neurable's co-founder and CEO Ramses Alcaide, a neuroscientist, told me. 'But when you're measuring from the source, you pick up those things as they're occurring, instead of once there's finally downstream consequences, and that's the real advantage of measuring the brain.' Other major tech companies are also exploring ways to incorporate non-invasive brain-computer interfaces into headphones. A couple years ago, Apple quietly patented an AirPod design that uses electrodes to monitor brain activity, and NextSense, which grew out of Google's moonshot division, wants to build earbud-based brain monitors for the mass market. There's also been a recent boom in activity around invasive brain-computer interfaces being developed by companies like Elon Musk's Neuralink and even Meta that surgically implant chips into people's brains. It's safe to say that's not currently a mass-market approach. Still, while all of those mega market cap companies ponder the possibilities of their own brain-powered projects, Neurable's is on the market. It's on my head right now, actually, and it works. The cutting edge of neurotech The Master & Dynamic MW75 Neuro — the $700 pair of headphones I tested — looks like any other set of noise-canceling headphones, except for the badge that reads, 'Powered by Neurable AI.' When you connect them to the Neurable app is when things get fun. Inside the Neurable app is a little video game that lets you fly a rocket ship with your brain — and serves as a proof of concept. The trick is you have to focus on a set of numbers on the screen. The more intensely you focus, the higher the numbers go, and the faster the rocket ship flies. If you start to get distracted by, say, thinking about flying an actual rocket ship, the numbers go down, and the rocket ship slows. It's one of the coolest innovations I've ever seen, if only because it's so simple. The EEG sensors in Neurable's products can pick up a range of brainwave frequencies, which are associated with different behaviors and activities. The beta frequency band provides some information about attention state as well as anxiety, while alpha indicates a mind at rest. While EEG sensors and brain-computer interfaces are most often seen in labs, putting these sensors into a device that people wear every day stands to transform our understanding of the mind. 'Non-invasive EEG is cheap and completely safe,' said Bin He, a professor of biomedical engineering at Carnegie Mellon University, whose lab built a drone you can fly with your mind over a decade ago. 'AI, or deep-learning technology, however has drastically improved the performance of [brain-computer interfaces] to read the minds of individuals.' If you changed the technology's mission from measuring focus to, say, symptoms of depression, you could imagine how an everyday gadget could offer some life-changing interventions. The possibilities are as endless as the list of issues that can affect the brain. The Pentagon has been using Neurable's portable technology to study traumatic head injuries in soldiers, for instance, and that research could have practical applications in sports. Alcaide also mentioned Alzheimer's and Parkinson's as potential targets for their technology. Symptoms for these diseases don't appear for years after onset, but early markers could show up in the kind of EEG data their technology captures from everyday wear. If you changed the technology's mission from measuring focus to, say, symptoms of depression, you could imagine how an everyday gadget could offer some life-changing interventions. For now, however, the MW75 Neuro headphones are primarily used to sharpen your attention — with the new and added benefit of giving you a snapshot of your brain health. This involves starting a session with the headphones on and letting the sensors collect the electrical signals your brain's sending off. Your focus is measured as low, medium, or high, and when you're flagging for a while, the app will prompt you to take a break. You can also turn on a feature called Biofeedback, which plays music of varying intensity in order to nudge your focus toward the high range. The Brain Health reports are still in beta mode but will show you daily estimates of how you're doing in terms of things like anxiety resistance, cognitive speed, and wakefulness. The way you know that the device isn't actually reading your mind comes down to science and a strong data policy. Neurable's technology picks up raw voltage — not actual thoughts — from your neurons and uses AI to decode the data and identify signals associated with focus, the company's co-founder Adam Molnar explained to me recently. Neurable encrypts and anonymizes the data coming out of your head and onto its sensors and then again when it goes to your phone, so it's far removed from any personal data. Furthermore, he said, Neurable has no ambitions to be a data company. 'Our business model doesn't depend on identity. We don't sell ads. So there's no benefit,' Molnar said. 'It's actually more of a liability for us to be able to have data map back to an individual.' It's hard for me to say how much more productive I became thanks to the brain-reading headphones. As with many other health trackers, there's sort of a placebo cat effect: Simply deciding to track the behavior changed my state of mind and made me behave a certain way. So, setting up a focus session inevitably made me pay closer attention to how well I was focusing, how often I took breaks, and if I was choosing to be more mindful. This is actually what makes me so curious about an earbud version of what Neurable's doing. I wear AirPods for most of the day, whether it's taking calls for work, listening to podcasts, or just drowning out the sounds outside my Brooklyn apartment. If these earbuds were also collecting data about my cognitive well-being during all those activities, I'd be interested in knowing what I could glean from that information, if only to better understand what's rotting my brain. And I'm sure plenty of companies would be happy to collect more data about their users' states of mind at any given time. Imagine if the TikTok algorithm knew you weren't interested in something — not because you swiped through it but rather because your brainwaves said so. Neurable's website has mockups of EEG-equipped earbuds, helmets, and smart glasses, and it's clear that the company is eager to move beyond its first product. The company doesn't just want to make gadgets, either. It wants to be the leading platform for brain-powered technology. 'Just like Bluetooth is in every single device, and everyone should have access to Bluetooth, we believe that everyone should have access to neuro tech,' Alcaide told me. We're years away from the most far-fetched applications of brain-computer interfaces, but we're heading in that direction. 'There's so many things you can do with neuro tech, whether it's tracking health conditions, whether it's controlling devices, whether it is understanding yourself better,' he said. 'It would be a disservice to the world if the only solutions that came out were our own.' Neurable is indeed one of many startups trying to bring neuro tech to the masses, although they're the only ones selling a product I'd actually wear in public. Several other EEG-based gadgets out there take the form of headbands, many of which are geared toward sleep health or meditation. A company called Emotiv, which also partnered with Master & Dynamic, will start selling its own EEG-equipped earbuds this fall. It remains to be seen if and when Apple will make brain-reading AirPods, but they've already partnered with a brain interface startup called Synchron, which allows people to control iPhones with their minds (Haven't you always wanted to become one with your iPhone?). This is where we circle back to the point where science fiction meets reality. We're years away from the most far-fetched applications of brain-computer interfaces, but we're heading in that direction. Whether that future ends up looking miraculous or like a Black Mirror episode is up to us — and to the companies, like Neurable, pioneering it.

Myanmar's junta-picked acting president dies
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UPI

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Myanmar's junta-picked acting president dies

Aug. 7 (UPI) -- Myanmar's junta-appointed acting President U Myint Swe died Thursday morning, weeks after he was declared unable to perform his mostly ceremonial duties due to Parkinson's disease. He was 74. Myint Swe died at 8:28 a.m. local time at the No. 2 Defense Services General Hospital, the National Defense Security Council said in a statement. Myint Swe, a former general, was vice president of Myanmar during the Feb. 1, 2021, military coup. He was appointed acting president after the country's civilian leader, Daw Aung San Suu Kyi, was arrested. According to the National Defense and Security Council, Myint Swe began experiencing "sluggishness in movement and the ability to consume food and nutrients" in early 2023, and was soon diagnosed with Parkinson's, which the U.S. Centers for Disease Control and Prevention calls is a progressive nervous system disorder that afects movement and has no cure. In April of last year, he received medical treatment at Singapore's Mount Elizabeth Medical Center. Then from late May to mid-June of this year, he received treatment again, this time at the No. 2 Defense Services General Hospital in Myanmar. According to officials, Myint Swe experience wight loss, loss of appetite, fever and a decline in cognitive function last month, and was placed on medical leave July 18 and then hospitalized on July 24. He was listed as in critical condition after being hospitalized in the Special Intensive Care Unit of the No. 2 Defense Services General Hospital, where he died Thursday morning. A period of mourning has been declared from Thursday to Monday, during which the national flag will be flown at half-mast. The coup of 2021 has upended the country, which has been embroiled in civil war since. According to the Assistance Association for Political Prisoners, more than 7,000 civilians have been killed by junta forces amid the civil war and 22,000 remain arbitrarily detained. The United Nations estimates 22 million are in need of assistance and more than 3.5 million have been displaced by the fighting.

Lysoway Therapeutics Awarded Grant from The Michael J. Fox Foundation to Advance TRPML1 Agonist to Treat Parkinson's Disease
Lysoway Therapeutics Awarded Grant from The Michael J. Fox Foundation to Advance TRPML1 Agonist to Treat Parkinson's Disease

Business Wire

timea day ago

  • Business Wire

Lysoway Therapeutics Awarded Grant from The Michael J. Fox Foundation to Advance TRPML1 Agonist to Treat Parkinson's Disease

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Lysoway Therapeutics, Inc., a biopharmaceutical company developing small molecule modulators of lysosomal ion channels, today announced that it has received a research grant from The Michael J. Fox Foundation for Parkinson's Research (MJFF). Support comes from MJFF's Parkinson's Disease Therapeutics Pipeline Program, which focuses on candidates with strong potential to slow or halt disease progression or alleviate burdensome symptoms for those living with Parkinson's disease. Lysoway Therapeutics funding of $2.93 million will support the preclinical and translational development of Lysoway's novel, highly brain-penetrant small molecule TRPML1 agonist. This funding will allow us to accelerate the preclinical development of our lead TRPML1 agonist, with the goal of initiating first-in-human clinical trials early in year 2026 Share The study aims to investigate whether activating TRPML1 by a novel, small molecule modulator, will enhance the lysosomal membrane calcium ion channel to restore lysosomal function and help with clearance of alpha-synuclein, the protein that is linked to the disease. 'We are honored to receive this generous grant from The Michael J. Fox Foundation,' said Valerie Cullen, PhD, Principal Investigator and SVP of Research and Translation at Lysoway. 'TRPML1 is a high value target due to its pivotal role in sensing and responding to cellular stress. By activating this ion channel, we can engage multiple beneficial pathways that restore autophagy/lysosomal homeostasis and bolster cellular resilience. Our lead development candidate is both orally bioavailable and highly brain-penetrant, offering strong potential to modify disease progression in Parkinson's Disease.' Yongchang Qiu, PhD, Founder and Chief Executive Officer of Lysoway Therapeutics, added 'This funding underscores growing confidence in TRPML1 as a compelling target for Parkinson's disease. It will allow us to accelerate development of our lead TRPML1 agonist and to establish key biomarkers for target engagement, with the goal of initiating first-in-human clinical trials early next year.'

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