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The Guardian
35 minutes ago
- The Guardian
RFK Jr's health department to halt $500m in mRNA vaccine research
The US Department of Health and Human Services said on Tuesday it would terminate 22 federal contracts for mRNA-based vaccines, questioning the safety of a technology credited with helping end the Covid pandemic and saving millions of lives. The unit, Biomedical Advanced Research and Development Authority, helps companies develop medical supplies to address public health threats, and had provided billions of dollars for development of vaccines during the Covid-19 pandemic. HHS said the wind-down includes cancellation of a contract awarded to Moderna for the late-stage development of its bird flu vaccine for humans and the right to purchase the shots, as previously reported in May. The US health agency said it was also rejecting or canceling multiple pre-award solicitations, including proposals from Pfizer, Sanofi Pasteur, CSL Seqirus, Gritstone and others. In total, the affected projects are worth 'nearly $500 million', the Department of Health and Human Services (HHS) said. Certain late-stage projects were excluded from the move 'to preserve prior taxpayer investment'. This is the latest development under US health secretary Robert F Kennedy Jr, a longtime vaccine skeptic who has been making sweeping changes to reshape vaccines, food and medicine policies. 'We reviewed the science, listened to the experts, and acted,' Kennedy said in a statement. Kennedy said the HHS is terminating these programs because data show these vaccines 'fail to protect effectively against upper respiratory infections like COVID and flu', but did not offer scientific evidence. 'We're shifting that funding toward safer, broader vaccine platforms that remain effective even as viruses mutate,' Kennedy said. HHS said the decision follows a comprehensive review of mRNA-related investments initiated during the Covid-19 public health emergency. Since taking office, Kennedy, who spent two decades sowing misinformation around immunization, has overseen a major overhaul of US health policy – firing, for example, a panel of vaccine experts that advise the government and replacing them with his own appointees. In its first meeting, the new panel promptly voted to ban a longstanding vaccine preservative targeted by the anti-vaccine movement, despite its strong safety record. He has also ordered a sweeping new study on the long-debunked link between vaccines and autism. Unlike traditional vaccines, which often use weakened or inactivated forms of the target virus or bacteria, mRNA shots deliver genetic instructions into the host's cells, prompting them to produce a harmless decoy of the pathogen and train the immune system to fight the real thing. Though in development for decades, mRNA vaccines were propelled from lab benches to widespread use through Donald Trump's Operation Warp Speed – a public-private partnership led by Barda that poured billions into companies to accelerate development. The technology's pioneers, Katalin Karikó and Drew Weissman, were awarded the 2023 Nobel prize in medicine for their work contributing 'to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times'.


The Independent
an hour ago
- The Independent
4 people die in crash of medical transport plane on Navajo Nation in northern Arizona
A small medical transport plane crashed and caught fire Tuesday on the Navajo Nation in northern Arizona, killing four people, the tribe said in a statement. A Beechcraft 300 from the CSI Aviation company left Albuquerque, New Mexico, with four medical personnel on board, according to the Federal Aviation Administration and other agencies. It crashed in the early afternoon near the airport in Chinle, about 300 miles (483 kilometers) northeast of Phoenix. 'They were trying to land there and unfortunately something went wrong,' district Police Commander Emmett Yazzie said. The crew was planning pick up a patient who needed critical care from the federal Indian Health Service hospital in Chinle, said Sharen Sandoval, director of the Navajo Department of Emergency Management. She said the plan was to return to Albuquerque. The patient's location and condition were not known Tuesday evening. Tribal authorities began receiving reports at 12:44 p.m. of black smoke at the airport, Sandoval said. The cause of the crash wasn't known, the tribe said. The National Transportation Safety Board and the FAA are investigating. Navajo Nation President Buu Nygren said in a social media post that he was heartbroken to learn of the crash. 'These were people who dedicated their lives to saving others, and their loss is felt deeply across the Navajo Nation,' he said. Medical transports by air from the Navajo Nation are common because most hospitals are small and do not offer advanced or trauma care. The Chinle airport is one of a handful of airports that the tribe owns and operates on the vast 27,000 square-mile (70,000 square-kilometer) reservation that stretches into Arizona, New Mexico and Utah -- the largest land base of any Native American tribe. In January, a medical transport plane crashed in Philadelphia, killing eight people. The National Transportation Safety Board, which is investigating the crash, has said the voice recorder on that plane was not working. ___ Associated Press journalists Hannah Schoenbaum in Salt Lake City and Felicia Fonseca in Flagstaff, Arizona, contributed to this report.


Powys County Times
an hour ago
- Powys County Times
Wes Streeting warned alcohol measures ‘are not sufficient' to stop harm
Government plans to tackle problem drinking 'are not sufficient to address the scale and complexity of harm', leading health experts have warned. Academics, medics and charities from around the country have urged ministers to take 'ambitious' action to tackle the 'scale of the current crisis'. The Government recently set out plans to improve the health of people in England over the next decade. But in a letter to Health Secretary Wes Streeting, shared with the PA news agency, experts said that the public 'want and deserve' more action to tackle the harms. 'As experts from across alcohol policy, health and treatment, we urge you to revisit the current approach to tackling alcohol harm and commit to an ambitious, evidence-based strategy that reflects the scale of the current crisis,' the letter states. 'The 10-Year health plan for England offered a once-in-a-generation opportunity to shift gear and deliver genuine preventative action that would reverse the rising rates of alcohol-related hospitalisations and deaths we have seen in recent years. 'While the introduction of mandatory alcohol labelling and increased support for community-led schemes is welcome, these measures alone are not sufficient to address the scale and complexity of harm.' The letter has been signed by 34 health leaders from leading health organisations including the Alcohol Health Alliance; the Royal College of Physicians; the Royal College of General Practitioners and the Royal College of Emergency Medicine. The 10 Year Health Plan for England, which was published last month, sets out plans to tackle harmful drinking through alcohol labelling, which will include health warning messages. The document also sets out proposed changes to no and low (NoLo) alcohol products and pledged support for community-led schemes to reduce alcohol harm. Before the 10 Year Plan was released there was speculation over whether the plan would include a ban on alcohol advertising. It was also reported that ministers were exploring the possibility of minimum unit pricing (MUP), a policy which sets the lowest price an alcoholic drink can be sold for. In the new letter, experts have called for a series of measures to tackle alcohol harms, including: – A call for the introduction of MUP in England, as seen in Scotland and Wales. Minimum unit pricing for alcohol was associated with a 13% decrease in deaths from alcohol consumption in Scotland, according to a new study. Read this and more in our latest issue: — The Lancet (@TheLancet) April 21, 2023 – Giving local authorities the power to regulate hours of sale and online deliveries of alcohol. – For advertising regulations for alcohol to be 'aligned' with those for foods high in fat, salt and sugar. – A change to alcohol tax, linking duties to inflation and ending 'cider exceptionalism'. – More funding and support for local alcohol care teams. The group stresses that 'alcohol is not just the problem of a few'. It points out that every year alcohol contributes to more than a million hospital admissions. And the experts said that across the UK, 30% of the adult population engage in 'risky drinking', and almost one in 25 of all new cancers are estimated to be linked to alcohol. The 10 Year Plan states: 'While many people enjoy a drink in moderation, 4% of people drink as much as 30% of alcohol consumed each year.' But it adds that the estimated total 'societal cost' of alcohol harm in England was £27.4 billion per year in 2021/22. The authors conclude: 'The public want and deserve action, and we stand ready to work with Government to deliver real progress. 'By taking meaningful and co-ordinated action now, the burden of alcohol harm can fall significantly within the term of this Government, with visible results for families, the NHS, crime, and the economy.' The Department of Health and Social Care said it will continue to consider the most effective interventions to reduce alcohol harms. A spokesperson said: 'As we shift from sickness to prevention through our 10-Year Health Plan, we will make it mandatory for alcoholic drinks to display health warnings and nutritional information. 'To improve drug and alcohol treatment services and recovery support in England, the Government has also provided an additional £310 million in 2025/26, on top of the public health grant.' A spokesperson for the Portman Group said: 'Whilst overall alcohol consumption and harms such as binge drinking, underage drinking and anti-social behaviour continue to fall, and the vast majority of people drink within the chief medical officer's low-risk guidance or not at all, we share concerns around rising deaths and those who continue to drink to harmful levels. 'We support further targeted and tailored measures aimed at this group to manage the complex, often interrelated issues underlying harmful consumption and back calls for the further rollout of alcohol care teams and greater integration of care pathways. 'As the alcohol industry regulatory body for marketing, we welcome the chance to work constructively with the Government on the proposals within its 10 year plan to help more consumers make an informed choice and drink moderately.' – Other signatories on the letter include representatives from: the Institute of Alcohol Studies; Alcohol Change UK; the Royal College of Surgeons of England; the Royal Society for Public Health; the British Society of Gastroenterology; World Cancer Research Fund; the Association of Anaesthetists; the Association of Directors of Public Health; the British Association for the Study of the Liver; the Medical Council on Alcohol and the British Medical Association.