Eli Lilly to roll out diabetes medicine in prefilled pen
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US pharmaceutical major Eli Lilly on Thursday announced its plan to launch blockbuster diabetes drug tirzepatide ) in KwikPen , a prefilled pen designed for once-a-week administration for single patients in the Indian market, two days after its rival Danish drug maker Novo Nordisk launched the weight loss drug Wegovy as a weekly injection in the country, intensifying competition in the booming obesity market.Eli Lilly said it received the approval of the Indian drug regulatory authority but did not comment on the launch timeline. The expected price of the pen device was also not disclosed. Once launched, the company said each pen will deliver four fixed doses of 0.6 ml and has been approved in six dose strengths including 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg.Wegovy, launched earlier this week, is expected to be in the pharmacies by the end of this month. The delivery device will contain four doses of 0.25 mg, 0.5 mg and 1 mg priced at '17,345 a month. This translates into a weekly cost of '4,366. The 1.7 mg dose will be priced at '24,280 per month, and 2.4 mg dose will be priced at '26,015.Anoop Misra, chairman of Fortis C-DOC, Centre of Excellence for diabetes, metabolic diseases and endocrinology said Mounjaro's dual mechanism may offer superior efficacy, however "wider adoption" will depend on the "price" of the device.Winselow Tucker, president and general manager of Eli Lilly India, said the approval of Mounjaro KwikPen marks a step forward in the care of people living with type 2 diabetes and obesity, offering a convenient way for patients to take their medication. Mounjaro reduces body weight and decreases fat mass by regulating appetite."With this approval, all six dosage options for Mounjaro will soon be available in India, supporting a more personalised approach to treatment and allowing healthcare professionals to tailor care based on individual patient needs and clinical goals," he said.Mounjaro is the first and only dual GIP (glucose- dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist, indicated as an adjunct to diet and exercise for the treatment of Type 2 diabetes and chronic weight management in adults with obesity or overweight, with one weight-related comorbidity.
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The budget has also included large ships in the infrastructure harmonized master list (HML) allowing purchase of ships on easier terms while providing basic customs duty exemption on raw materials, components, consumables or parts for the manufacture of ships extended for another ten years. Formal government notification for these programmes is still awaited. As per Maritime Vision 2030 and Vision 2047 plan, government is targeting to make India among the top 10 and among top five shipbuilding and ship owning country's worldwide respectively. Overall investment of ₹3 to 3.5 lakh crore across ports, shipping, and inland waterways categories is targeted. The shipbuilding initiative would also address a concern of the trade about the uncertainty and variability (escalation) of shipping cost impacting their market competitiveness. With better availability of domestic shipping lines at affordable prices, the freight rate volatility due to black swan events like covid-19, the Russia-Ukraine war, Red Sea crisis, Iran-Israel conflict, etc, could also be checked.
