How often should you wash your sheets? You might not like the answer
The average American changes their sheets every 24 days, according to a Sleep Advisor survey. That's far less frequent than what health experts recommend. We spoke with Dr. Shoshana Marmon, a board-certified dermatologist, and Dr. Sakina Bajowala, an immunologist and medical director at Kaneland Allergy and Asthma, to get the lowdown on how often you should really be washing your bedding — including blankets, pillowcases, mattress covers, pillows and even your mattress. Turns out, unless you like sleeping in a petri dish, this is one chore you shouldn't put off.
Here's what to know about how often you should wash your sheets, blankets and other bedding, and why it matters.
Your sheets are in constant contact with your skin, so it's no surprise that both Marmon and Bajowala recommend washing them once a week. Think of it like changing clothes — you wouldn't wear the same outfit for a week without washing it; your sheets deserve the same treatment.
Sleeping for eight hours a night means you're exposed to sweat, oils, dead skin, dust and more for 56 hours every week. Over time, that buildup attracts dust mites, which can lay up to 50 eggs every few weeks. The longer you wait to wash your sheets, the more you invite these microscopic pests into your bed.
If you have sensitive skin, eczema, acne, psoriasis, or if you sweat a lot (or share your bed with pets), Marmon advises washing your pillowcases and sheets even more frequently.
To make your laundry routine easier, it's smart to keep a few sheet sets in rotation. If you're in the market for new bed sheets, a viscose and bamboo blend is great for comfort, but if you tend to sleep hot, consider investing in a good set of cooling sheets.
Because your pillowcases spend hours in direct contact with your face and hair, they're quick to collect oils, dirt and anything your hair picks up during the day. That grime doesn't just stay put — it can work its way into your pores while you sleep, potentially leading to breakouts, irritation and even eye infections.
"Washing your pillowcases at least once a week is generally recommended to maintain good skin hygiene," Marmon says.
And if you use hair products, sleep in makeup or skip nighttime showers, you might want to toss them in the wash more often. If you've had a recent cold, toss them in the wash tonight. If you're in a pinch, flipping your pillow mid-week can give you a slightly fresher surface until laundry day.
Even if your comforter isn't in direct contact with your skin, it's still picking up oils and sweat, especially if you tend to cuddle it or skip the top sheet. Without that extra layer acting as a barrier, your comforter requires weekly washing along with your other bedding.
Use a top sheet? You've bought yourself some extra time. In that case, Marmon says your comforter only needs to be washed every one to two months. If you use a duvet cover, be sure to wash it monthly — and you can go longer between cleanings for the insert.
Can't remember the last time your comforter or duvet saw the inside of a washer? Play it safe and toss it in the wash this week.
The answer depends on which type of mattress protector you have. If you have a vinyl mattress protector, Bajowala says to wipe it down every time you wash your sheets and let it air dry.
If you have a cloth mattress protector that isn't tightly woven, she says those aren't very helpful for keeping dust mites off your mattress and instead recommends using a tightly woven allergen cover. "Dust mite covers and allergen covers are designed to be tightly woven so the space between the threads is microscopic and allergens can't get through." Those typically only need to be washed once a month.
You may not think about your pillows much since they're covered by pillowcases, but you should be washing them too. Marmon recommends giving them a good cleaning every 3 to 6 months. You can extend that time if you use pillow protectors — I use these. Make sure you check the cleaning label before you toss your pillows into the washer and dryer: some, like feather pillows, may have special instructions.
Since pillows can also harbor dirt, oil, sweat, dust mites and dead skin (and inevitably lose support over time), Marmon recommends replacing them altogether every 1 to 2 years. If it's past that time for you, take a look at our list of the best pillows for every type of sleeper.
If you've spent any time on CleanTok (that's code for the cleaning videos on TikTok), you've probably seen creators vacuuming their mattresses. While the thought of standing on your bed vacuuming might sound crazy, it actually works to remove those dust mites and dead skin cells. (A cordless vacuum may be easier to work with here.)
"Vacuuming your mattress helps eliminate dust mites, dead skin cells and allergens," says Marmon. Bajowala agrees, adding that "using a HEPA filter-equipped vacuum can remove dust mites and their particles." However, she emphasizes that you should vacuum your mattress monthly to reap the benefits and warns that vacuuming alone is insufficient. You still need to wash your bedding regularly in hot water and manage indoor humidity to ensure your bed stays clean and fresh.
Bajowala recommends washing your sheets at the highest temperature the fabric can withstand. "The sterilize cycle or 130°F will get the job done," she says, when it comes to killing dust mites.
That said, not all sheets can take the heat, so always check the care label first. For example, some bamboo sheets are labeled for cold water only, while silk sheets should definitely avoid hot water due to how delicate they are (which is why I've never taken the plunge on buying a set). Cotton, on the other hand, tends to be more durable and can usually handle higher temps.
Still, Bajowala cautions, "Don't buy bedding that can't be washed in hot water," especially if you're sensitive to dust mites. "People with dust mite allergies shouldn't purchase those types of sheets."
While there's no universal rule for how often you should wash your sheets, once a week is a good baseline, especially if you're not showering at night or you share your bed with pets. That said, small changes can help stretch the time between washes: rinse off before bed, keep furry companions off the covers and rotate your pillowcases midweek. And while more frequent washings might feel like one more thing to pile onto your already long to-do list, there is something undeniably satisfying about climbing into freshly washed sheets.

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


CNN
2 hours ago
- CNN
Fast walking is a key to longevity, research shows
Wellness Heart diseaseFacebookTweetLink Follow Too busy to go to the gym? Don't worry — you can stay healthy by incorporating at least 15 minutes of fast walking into your everyday routine, new research suggests. In general, it's recommended that people commit to 150 minutes of moderate activity per week to see sufficient health benefits, said Dr. Wei Zheng, the study's corresponding author. But if 150 minutes is too difficult to manage, fast walking a minimum of 15 minutes every day can have the same health benefits. Zheng and a team of researchers recruited mostly low-income and Black study participants from 2002 to 2009, according to the study published in the American Journal of Preventative Medicine. The nearly 85,000 participants were given a comprehensive questionnaire about their exercise habits, average time spent working out, walking speed and health. Then the participants complete a questionnaire about 16 years later, and the analysis began in 2023. We know 'fast walking is good compared to slow walking,' but there isn't much research on how many minutes you should spend fast walking on average, said Zheng, director of the Vanderbilt Epidemiology Center and the Anne Potter Wilson Professor in Medicine at Vanderbilt University Medical Center in Nashville, Tennessee. On average, study participants who fast walked for at least 15 minutes every day saw a nearly 20% reduction in premature death compared with a 4% reduction among participants who walked slowly for a total of more than three hours a day. 'We've actually known for quite a long time that walking speed correlates with outcomes, meaning the faster you walk, the better you do. And it certainly makes sense, because you can imagine, somebody who's in really bad shape is probably not going to be able to walk very quickly,' said Dr. Andrew Freeman, director of cardiovascular prevention and wellness at National Jewish Health in Denver. He was not involved in the study. Walking has health benefits, such as managing weight and sugar intake, reducing risk of cancer, easing joint pain, and boosting immune function. Health experts 'know that when people are exercising regularly, blood vessels can relax and dilate a bit better. And then we also know that exercise is quite good for cholesterol, so it seems to lower cholesterol, and then overall, it reduces the risk of cancer and things that would otherwise hurt people,' Freeman said. Walking daily can also lower risk of dementia or cognitive decline in people predisposed to developing Alzheimer's, according to recent research. Engaging in daily physical activity, such as walking, promotes better sleep and reduces inflammation, which improves brain structure, according to the Piedmont Medical Center in South Carolina. 'I want to emphasize that these exercises, no matter slow or fast, all confirm some benefit,' Zheng said. 'But what we find is that fast walking as little as 15 minutes a day confirms substantiated benefits.' Fast walking has been found to have specific benefits, such as decreasing risk of heart failure, arrythmias and type 2 diabetes. '(T)he thought is that exercise has a very big effect on blood pressure, as you may know, and blood pressure, it is one of the more exponential risk factors that we have, for roughly every 20 points blood pressure goes above 120 (what is considered normal or healthy), the risk of a cardiac event roughly doubles,' Freeman said. 'So, it's a super potent and exponential risk factor, and we know that regular exercise lowers that.' In general, you can tell you're fast walking when you're able to talk but not sing, according to the United Kingdom's National Health Service. Alternatively, you can increase your walking pace by a couple of steps and track it with a metronome, according to a July study. 'I usually recommend that they get up before work, and they go for a brisk walk or a bike or a swim, or they do some high-intensity interval training, whatever it is that they're into,' Freeman said. People can go to 'a rec center, or they walk outside, if it is safe, or whatever it may be, and just weave it into their day.' Following good walking form, such as standing tall with your shoulders back and swinging your arms, can help prevent backaches, make it easy to breath and keep you balanced. 'Walking is a full body movement. It is not just about your lower body. It's not just one step in front of the one foot in front of the other,' said Dana Santas, a certified strength and conditioning specialist and mind-body coach in professional sports, in a previous article. 'Your arm swing is a huge part involved in the mechanics of walking. So, you want to have an arm swing that's coordinated with your foot movement, so it's opposing,' she added. Want to take it up a notch? When doing any form of exercise, try to practice conscious or nasal breathing, which is when you inhale through your nose and exhale through your mouth. This helps regulate blood pressure and can prevent hypertension, according to Santas. Sign up for CNN's Fitness, But Better newsletter series. Our seven-part guide will help you ease into a healthy routine, backed by experts.
Yahoo
3 hours ago
- Yahoo
Eat most of your calories by 7 p.m., wear toe spacers and skip the fries — plus 9 more health tips to help you have a great week
Plus: Why you should sip green tea. Hello, Yahoo readers! My name is Kaitlin Reilly, and I am rounding up the best health and wellness tips the internet has to offer this week. Do you start the morning with a glass of OJ? A potential change to orange juice is coming, thanks to a new regulation proposed by the Trump administration calling for it to be made with less sugary oranges, the Washington Post reports. The Food and Drug Administration is proposing to lower the minimum sugar content required for orange juice to be labeled as 'pasteurized orange juice,' in response to a request from Florida's citrus industry, which is struggling with declining sugar levels in its crops. The change would slightly reduce sugar per serving but wouldn't significantly affect taste or nutrition. But while orange juice has long been a staple of the classic American breakfast, is it really a good option to start your morning? Maybe not, nutrition experts tell the Washington Post. Barry Popkin, a professor of nutrition at the University of North Carolina, calls orange juice — and every juice — nothing more than 'sugar water,' and that remains true even if it's made with slightly less sugar. And while orange juice does contain calcium and vitamin C, you're far better off eating a real orange, which has fiber that can balance out your blood sugar levels and keep you from crashing. While you rethink your a.m. beverage, we're here to help you get ready for the week ahead. Take a look at your local weather forecast, then check out your horoscope to gather any intel from the stars. Finally, pick 'one small thing' to do this week to improve your well-being. Here are some tips … 🕰️ Eat most of your calories by 7 p.m. Our bodies are better equipped to use food for energy between the morning and early evening — but things slow down post-sunset, dietitian Colin Popp tells Today. As such, he recommends an approach he calls 'front-loading,' which means getting the majority of your calories earlier in the day (think: a hearty breakfast and/or lunch, followed by a lighter dinner around 5 to 7 p.m.). This, he explains, better aligns with your circadian rhythm and may boost metabolism, blood sugar control and even sleep. And since research shows that eating at night is associated with weight gain and unstable blood sugar levels (which can lead to chronic health issues over time), it's best to avoid big or heavy meals shortly before bedtime. An easy way to break down your daily calorie intake is to aim for 25% to 40% at breakfast, 30% to 40% at lunch and 15% to 20% at dinner, with snacks making up the rest of your day. 🦶 Step up your foot game Giving your feet a little TLC can help you avoid pain and improve mobility and strength. Dana Santas, a strength and conditioning specialist, tells CNN that she recommends her clients roll their bare feet over a textured ball twice a day, making sure to shift position every 30 seconds to target different areas of the foot. Don't have a textured ball? A golf or lacrosse ball works too in a pinch. Another easy way to ensure you're giving your feet proper care? Try wearing toe spacers for 15 to 20 minutes a night, Santas says. You'll fight foot fatigue and counteract the effects of restrictive footwear. 🍟 Skip the fries We're so sorry to tell you this: Research published in the BMJ found that eating these fast food favorites often — about three servings per week — can raise your risk of type 2 diabetes by up to 20%. Those who ate baked, boiled, or mashed potatoes did not see a large rise of their risk, however. While the link between french fries and diabetes was not clear from the research, experts tell Women's Health that it could be related to the overall eating habits of people who eat them frequently. (For example, if you're hitting up the drive-through multiple times a week instead of eating nutrient-dense meals.) Plus, dietitian Jessica Cording points out that it's easy to eat large quantities of fries at once. You don't have to give up fries entirely, experts say. Just eat them alongside fiber-packed veggies and lean proteins and make the majority of your meals as nutritious as possible. An occasional bag of fries shouldn't raise your diabetes risk much if eaten as part of a balanced diet. 🏠 Consider a HEPA filter Live near a busy road? You could be exposed to indoor air pollution, which can cause high blood pressure. And if moving isn't an option, consider new research that suggests using HEPA air purifiers. As NBC News reports, a study published in the Journal of the American College of Cardiology found that participants with elevated blood pressure saw lowered systolic blood pressure readings after using HEPA filters for a month. While those with normal blood pressure saw no change, these filters could be a good call for anyone concerned about their numbers and the pollution around them. 🍔 Add this 1 thing to your burger Give your burger an upgrade by adding something plant-based to your ground beef, Today suggests. Mushrooms are a great pick, from both a flavor and a health standpoint. They boast good-for-you nutrients like vitamin D, selenium, potassium and B vitamins, and because they're low in calories, adding them to your patty mix (and cutting down on the beef) keeps your burger from being such a calorie bomb. 📺 Scale back screen time A study published in the Journal of the American Heart Association found that too much screen time can come with health risks for children. Looking at 1,000 kids who spent time on screens like gaming consoles, smartphones and TVs, researchers saw that those with higher amounts of screen time were at a greater risk of heart and metabolic issues, like high blood pressure and insulin resistance. One potential reason the researchers gave, according to CBS News, is that screen time can cut into all-important sleep, pushing bedtimes later and reducing overall hours snoozing. While the study only looked at 10- and 18-year-olds, it stands to reason that people of all ages could benefit from a little less scrolling and a lot more sleep. If you're prone to staying up watching TikToks in bed, try reading a book instead; you'll be more likely to doze off and get better rest. 🏋️ Take baby steps with that new fitness plan This is going to be the week you jump-start a new workout routine. But if you're rusty in the exercise department, experts warn against overdoing it, Women's Health reports. Signing up for an intense, early-morning boot camp or challenging yourself to use your monthly gym pass every day might not be sustainable over time. Personal trainer Kristen McParland says that it's 'really difficult for a beginner to go from zero days to five.' It's better to 'smart small and build,' she advises. Maybe that's hitting an exercise class twice a week to start, or going for a run on Sunday mornings until you get into a nice groove. And don't push yourself to work out in the mornings if you loathe getting up early — you'll eventually abandon your routine. As McParland says, the 'best time' to work out is the one that works for you and your body. 🍪 Cut back on ultraprocessed foods Need one more reason to cut out ultraprocessed foods, such as packaged cookies and chips? A new study published in Thorax found that eating them could up your risk of lung cancer, Prevention reports. While it's unclear what is behind this association, it's not the first study to find negative impacts of ultraprocessed foods, which can often be higher in sugar and fat, as well as lower in fiber, vitamins and minerals, than whole food options. One way to combat the health risks of ultraprocessed foods is to aim for whole foods (vegetables, fruit, meat, fish, nuts and eggs) whenever possible. 🐟 Eat fatty fish for better cholesterol When we think of cholesterol, we often think about reducing our 'bad cholesterol' — aka LDL, which can build up in the arteries and increase the risk of heart disease. But you also need to think about your 'good cholesterol,' called HDL, which helps remove excess cholesterol from the bloodstream. One way to do that, our friends at EatingWell say, is to add more fatty fish, like salmon, mackerel and sardines. to your diet. They're rich in omega-3s, which have been shown to boost HDL and reduce inflammation in the body. Keep things simple by going with the tinned fish variety, which you can add to a salad or eat alone with a cracker. 😋 Go for cumin Time to spice things up. Adding cumin to your meals could come with gut health benefits, the Independent reports. The warm, nutty spice is rich in antioxidants, and past research has found that it can help alleviate symptoms of irritable bowel symptom, such as uncomfortable bloating. If you want the most out of cumin, make sure to grind it up: it'll help your body absorb some of its other nutritional perks, such as B vitamins, vitamin E, iron and magnesium. 🍵 Drink tea Break out the kettle. Drinking certain teas can help you manage your blood pressure, cardiologist Dr. Ragavendra Baliga tells Prevention. Why? These teas — particularly green and hibiscus — contain blood vessel-widening polyphenols, which allows for better blood flow and oxygen delivery to the rest of your body. Just stick to a couple of cups a day, and be aware of any side effects or medicine interactions. 🥛 Don't mix these meds with dairy You've probably heard that grapefruit can interfere with certain medications, but dairy can cause problems too. According to EatingWell, foods like milk, yogurt and cheese can block the absorption of medications such as tetracycline antibiotics and certain types of quinolone antibiotics, like ciprofloxacin. It's also best to avoid dairy for at least four hours before taking levothyroxine (for thyroid issues), lithium (for bipolar disorder) and eltrombopag (used to boost platelet count). Got the flu and were prescribed baloxavir? Skip not only dairy but also other calcium-rich foods like sardines — or even Tums, which contain 500 mg of calcium carbonate — since they can interfere with how the drug works.
Yahoo
5 hours ago
- Yahoo
NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) Granted FDA Fast Track Designation for NRX-100 for Suicidal Ideation in Patients with Depression, including Bipolar Depression
This designation expands the addressable population for NRX-100 to the 13 million Americans who consider suicide each year and represents a 10x expansion of the addressable population compared to the Designation granted in 2017 for bipolar depression alone The Designation includes an FDA determination that NRX-100 has the potential to address an unmet need, based on FDA's assessment of the data submitted Determination of "unmet need" is a requirement for a Commissioner's National Priority Voucher (CNPV) program. Suicide is a public health crisis. Approximately 13 million adults seriously consider suicide each year, according to the CDC, 3.7 million make a plan to commit suicide. An American dies from suicide every 11 minutes. Active-duty personnel, veterans, and first responders have a four-fold higher risk of suicide. WILMINGTON, Del., Aug. 11, 2025 /PRNewswire/ -- NRx Pharmaceuticals, Inc. (Nasdaq:NRXP), a clinical-stage biopharmaceutical company, today announced US Food and Drug Administration (FDA) has granted Fast Track designation to NRX-100 for the treatment of suicidal ideation in patients with depression, including bipolar depression. This designation for NRX-100 as a standalone drug is a 10-fold expansion of the addressable population for NRX-100, compared to the designation granted in 2017 for NRX-100 in combination with NRX-101 (DCS/lurasidone) for treatment of Suicidal Bipolar Depression. In granting the Fast Track designation, FDA made the determination that NRX-100 has the potential to address an unmet medical need, based on an assessment of the preliminary data contained in the Fast Track designation request. This determination of unmet medical need aligns with the eligibility requirements for the Commissioner's National Priority Voucher Program (CNPV)i and for the FDA's Accelerated Approval The Company has applied for a CNPV, which has the potential to substantially shorten the review cycle for NRX-100. Several well-controlled trials submitted to FDA in support of Fast Track Designation demonstrated a clinically meaningful and statistically significant reduction of suicidal ideation. In a Columbia University study licensed by NRx, suicidal patients treated with intravenous ketamine demonstrated a 55% response (i.e. 50% reduction in suicidality) compared to a 30% response to active comparator (P<.02).iii In a trial sponsored by the Government of France and licensed by NRx, 63% of patients achieved full remission from suicidal ideation in three days compared to 31% of those who received placebo (P<.001). This effect has not been proven with intranasal administration of "We thank FDA for its thoughtful review of our Fast Track designation request, and believe this regulatory determination is a significant step forward in our goal to address the national crisis of suicide among soldiers, first responders, veterans, and civilians alike." said Dr. Jonathan Javitt, Chairman and CEO of NRx Pharmaceuticals. "Large-scale government-supported trials have demonstrated a robust and statistically significant reduction in suicidal ideation and depression with administration of ketamine. This drug was also proven to be non-inferior to electroshock therapy in treating depression without the negative side effects of ECT. We look forward to working closely with the FDA in our quest to Bring Hope to Life." Under the terms of the Fast Track program, NRx will be posting an expanded access policy for NRX-100 in the next two weeks and seeking a meeting with FDA leadership to finalize the data to be submitted under the Accelerated Approval / CNPV application. In addition to the benefits above, Fast Track Designation also grants enhanced communication with the FDA, as well as potential Priority Review and Rolling Review. NRX-100 in Suicidal Ideation in Patients with Depression, Including Bipolar Depression According to the CDC, approximately 13 million adults seriously consider suicide each year, 1.5 million attempt suicide, and an American dies from suicide every 11 minutes. NRX-100 – IV ketamine for suicidality in patients with depression, including bipolar depression – is designed to help address this national crisis. NRx will be submitting patient-level data from controlled clinical trials that demonstrate ketamine to be superior to both a placebo and an active comparator, as well as either non-inferior or superior to electroshock therapy in treating various forms of depression, including patients with active suicidal ideation. Although ketamine in various forms is increasingly used to treat depression and related disorders, it is currently only approved by FDA only for use as an anesthetic and, therefore, not reimbursed by most insurance carriers for treatment of suicidality or depression. Intravenous ketamine is reimbursed by the Department of Veterans Affairs and the Department of Defense for its beneficiaries. By applying for FDA labeling for NRX-100 to treat suicidal depression, the Company hopes to make this potentially life-saving therapy available to all Americans, not just those who are able to pay out of pocket. The Company has previously filed full Chemical Manufacturing and Controls (CMC) information for NRX-100 with FDA and has reported stability and sterility data sufficient to anticipate three-year room temperature shelf life for preservative-free ketamine. Having completed this Fast Track Designation, NRx is now filing draft labeling for NRX-100 to comply with the CNPV requirement. NRX-100 is the first preservative-free presentation of ketamine to be filed with FDA. Currently available product, primarily of foreign manufacture, contains a known toxic preservative, Benzethonium Chloride (BZT) that is not Generally Recognized as Safe (GRAS) and is not allowed by FDA to be used in hand cleaners and topical antiseptics. NRx demonstrated long term stability and sterility with its patented preservative-free formulation of NRX-100. The Company has additionally filed a Citizen Petition seeking to have BZT removed from all intravenous ketamine products. The Company has instituted US-based high-volume manufacture of sterile, preservative-free ketamine. Regarding Fast Track designation, FDA's website states: A drug that receives Fast Track designation is eligible for some or all of the following: More frequent meetings with FDA to discuss the drug's development plan and ensure collection of appropriate data needed to support drug approval. More frequent written communication from FDA about such things as the design of the proposed clinical trials and use of biomarkers Eligibility for Accelerated Approval and Priority Review, if relevant criteria are met. Rolling Review, which means that a drug company can submit completed sections of its Biologic License Application (BLA) or New Drug Application (NDA) for review by FDA, rather than waiting until every section of the NDA is completed before the entire application can be reviewed. BLA or NDA review usually does not begin until the drug company has submitted the entire application to the FDA. NRX-100 is poised to address the >$3 billion Suicidal Depression market in the US. References i Grunebaum, et al. Ketamine for rapid reduction of suicidal thoughts… Am J Psychiatry 2018;175: Abbar, et al. Ketamine for the acute treatment of severe suicidal ideation… BMJ 2021;167:194-203 About NRx Pharmaceuticals, Inc. NRx Pharmaceuticals is a clinical-stage biopharmaceutical company developing therapeutics based on its NMDA platform for the treatment of central nervous system disorders, specifically suicidal depression, chronic pain, and PTSD. The Company is developing NRX-100 (preservative-free intravenous ketamine) and NRX-101, (oral D-cycloserine/lurasidone). NRX-100 has been awarded Fast Track Designation for the treatment of Suicidal ideation in Depression, including Bipolar Depression. NRX-101 has been awarded Breakthrough Therapy Designation for the treatment of suicidal bipolar depression. NRx has recently filed an Abbreviated New Drug Application (ANDA) and initiated a New Drug Application filing for NRX-100 (IV ketamine) with an application for the Commissioner's National Priority Voucher Program for the treatment of suicidal depression. The filing is based on results of well-controlled clinical trials conducted under the auspices of the US National Institutes of Health and the Government of France, licensed under a data sharing agreement. Notice Regarding Forward-Looking StatementsThe information contained herein includes forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as "may," "will," "should," "would," "expect," "plan," "believe," "intend," "look forward," and other similar expressions among others. These statements relate to future events or to the Company's future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. The Company has reported regulatory milestones as they have been achieved but has not predicted the outcome of any future regulatory determination. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects the Company's current views with respect to future events and is subject to these and other risks, including uncertainties and assumptions relating to the Company's operations, results of operations, growth strategy, and, among other things, liquidity. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company's most recent Annual Report on Form 10-K and other filings with the Securities and Exchange Commission. Investors and security holders are urged to read these documents free of charge on the SEC's website at Except as may be required by applicable law, the Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, whether as a result of new information, future events or otherwise. For further information: Matthew Duffy Chief Business Officer, NRx Pharmaceuticals mduffy@ Brian Korb Managing Partner (917) 653-5122 View original content to download multimedia: SOURCE NRx Pharmaceuticals, Inc. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data