Agilus launches new antibody test for diagnosing arthritis
Agilus Diagnostics
, in collaboration with
Sebia
, has launched an Anti-MCV (anti–mutated citrullinated vimentin) antibody test that provides
early detection of rheumatoid arthritis
(RA).
Developed by Sebia, the new antibody test enhances the early detection of rheumatoid arthritis (RA), especially in patients who test negative for conventional markers like anti-CCP and rheumatoid factor (RF).
'Studies show that 10–15 per cent of RA cases missed by anti-CCP can be picked up through anti-MCV testing. When patients present with persistent symptoms but test negative for both CCP and RF, anti-MCV offers clinicians a valuable next step,' a statement from the company spokesperson reads.
The new antibody test is a highly sensitive and specific biomarker, which detects autoantibodies against a mutated form of the vimentin protein particularly valuable for identifying RA in individuals who test negative for conventional markers such as anti-CCP and rheumatoid factor (RF), the company said.
Clinical data also supports the combined use of anti-MCV and anti-CCP to enhance diagnostic accuracy. When used together, these tests can increase sensitivity without compromising specificity, helping to identify RA in its earliest stages, when therapeutic intervention can make the greatest difference, it added.
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New Delhi: Agilus Diagnostics , in collaboration with Sebia , has launched an Anti-MCV (anti–mutated citrullinated vimentin) antibody test that provides early detection of rheumatoid arthritis (RA). Developed by Sebia, the new antibody test enhances the early detection of rheumatoid arthritis (RA), especially in patients who test negative for conventional markers like anti-CCP and rheumatoid factor (RF). 'Studies show that 10–15 per cent of RA cases missed by anti-CCP can be picked up through anti-MCV testing. When patients present with persistent symptoms but test negative for both CCP and RF, anti-MCV offers clinicians a valuable next step,' a statement from the company spokesperson reads. The new antibody test is a highly sensitive and specific biomarker, which detects autoantibodies against a mutated form of the vimentin protein particularly valuable for identifying RA in individuals who test negative for conventional markers such as anti-CCP and rheumatoid factor (RF), the company said. Clinical data also supports the combined use of anti-MCV and anti-CCP to enhance diagnostic accuracy. When used together, these tests can increase sensitivity without compromising specificity, helping to identify RA in its earliest stages, when therapeutic intervention can make the greatest difference, it added.
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