EXCLUSIVE Just one glass of America's favorite drink 'turbocharges' risk of deadliest form of colon cancer, doctors warn
For many Americans, cracking open a soda is a small daily indulgence — a fizzy treat paired with an otherwise balanced lifestyle.
But a new study suggests that even this seemingly innocent habit could be turbocharging one of the deadliest forms of cancer striking young people today.
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Daily Mail
23 minutes ago
- Daily Mail
Major HIV breakthrough forces hidden fragments of the virus to emerge so it can be cleared from the body
Experts could have found a way to be one step closer to curing HIV for good. Researchers in Australia has developed a new treatment that forces hidden fragments of the virus - normally concealed within human cells - to emerge and expose themselves to the immune system. The breakthrough could enable the body, aided by antiviral drugs, to detect and destroy any lingering viral reservoirs. HIV has remained incurable because the virus can integrate itself into a cell's DNA, laying dormant and undetectable to both medication and immune defenses. Scientists said they've created a nanoparticle capable of delivering genetic instructions to infected cells, prompting them to produce a signal that reveals the virus's presence. Dr Paula Cevaal of the Doherty Institute and co-author of the study told The Guardian that the feat was 'previously thought impossible'. Cevaal said: 'In the field of biomedicine, many things eventually don't make it into the clinic, that is the unfortunate truth; I don't want to paint a prettier picture than what is the reality. 'But in terms of specifically the field of HIV cure, we have never seen anything close to as good as what we are seeing, in terms of how well we are able to reveal this virus. 'So, from that point of view, we're very hopeful that we are also able to see this type of response in an animal, and that we could eventually do this in humans.' The discovery was first revealed in the journal Nature Communications, where researchers said they were initially so astonished that they had to rerun the tests. Further research would be needed to determine whether revealing the virus would be enough to trigger an immune response, with tests only being carried out in the lab. It could still take years before clinical trials for the drug began, when it would have to go through rigorous testing before reaching consumers. However, the advance represents another step forward for the 1.2 million Americans currently living with an HIV infection - for which they took drugs daily. An estimated 31,800 people were believed to be infected every year, although that's a 12 per cent decline on five years ago. Globally, nearly 40 million people have the virus. The new nanoparticle's based on mRNA technology, the same as was used in covid vaccines made by Pfizer and other vaccine manufacturers. In their paper, the scientists revealed that they could deliver mRNA instructions to cells using the nanoparticle. The mRNA then instruct cells to generate substances that reveal the presence of HIV, but only if the virus was present. The study done in the laboratory was carried out in cells donated by HIV patients.
Daily Mail
24 minutes ago
- Daily Mail
Earth's CO2 hits highest recorded level in human history, experts say
There's now more carbon dioxide (CO2) in the atmosphere than ever before in human history, scientists have revealed. For the first time on record, monthly average CO2 levels exceeded 430 parts per million (ppm), according to experts at Scripps Institution of Oceanography in San Diego. The monthly average for May 2025 reached 430.2ppm – the highest level since accurate measurements began 67 years ago. The more CO2 in the atmosphere, the higher the rate of global warming , which could one day could make Earth's surface too hot for humans. At much higher concentrations, CO2 can also cause a variety of health issues. Worryingly, this includes cognitive impairment, drowsiness, nausea and even death in the most extreme cases. 'Another year, another record,' said Ralph Keeling, director of the Scripps CO2 Program. He added: 'It's sad.' Like other greenhouse gases, CO2 acts like a blanket, trapping heat and warming the lower atmosphere. This changes weather patterns and fuels extreme events, such as heat waves, droughts, wildfires, heavy rain and flooding. Rising CO2 levels also contribute to ocean acidification , which makes it more difficult for marine organisms like crustaceans and coral to grow hard skeletons or shells. The experts' new measurements come from Mauna Loa Observatory, a research station situated high on the slopes of the Mauna Loa volcano, Hawaii. At 11,141 feet above sea level, Mauna Loa Observatory measures different gases in the air by shining different kinds of light and radiation through air samples. According to the experts, the observatory's monthly average for May 2025 of 430.2 ppm is an increase of 3.5 ppm over May 2024's measurement of 426.7 ppm. Meanwhile, NOAA's Global Monitoring Laboratory in Boulder, Colorado has separately reported an average of 430.5 ppm – an increase of 3.6 ppm over last year. In a post on X , Jeff Berardelli, meteorologist and climate specialist for WFLA Tampa Bay, called the new record 'concerning'. CO2 is by far the most abundant human-caused greenhouse gas and it can persist in the atmosphere and oceans for thousands of years. According to scientists, the amount of carbon present now in the Earth's atmosphere is equal to that which would have been seen some 4.1 to 4.5 million years ago, during a time which scientists refer to as the 'Pliocene Climatic Optimum'. At this time, the sea level was a whopping 78 feet (24 meters) higher than in the present day, while the average global temperature stood at 7°F (3.9°C) higher than it was before the Industrial Revolution. In fact, the temperature was so warm during this period of time that large forests occupied areas of the Arctic which today are barren, chilly tundra. Although humanity is constantly pumping out CO2 all-year-round, atmospheric CO2 is at its highest in the Northern Hemisphere in the spring – specifically May. Between autumn and spring, much of the hemisphere's plant matter decomposes, releasing CO2 into the atmosphere as it does so. May tends to represent the highest extend of atmospheric CO2 before plants come to life and draw in CO2 to fuel their growth. This begins the process of lowering the amount of CO2 in the atmosphere until the autumn when the plants start to die – and the cycle continues. Researchers say Mauna Loa Observatory's new measurements represent the average state of CO2 in the atmosphere of the Northern Hemisphere. However, CO2 concentrations have not yet passed the 430 ppm mark in the Southern Hemisphere, which has a reversed cycle. It was Scripps scientist Charles David Keeling, father of Ralph Keeling, who was the first to recognise that CO2 levels in the Northern Hemisphere peaked in May. In 1958, he began monitoring CO2 concentrations at Mauna Loa Observatory and documented a long-term increase, known as the Keeling Curve. NOAA's Global Monitoring Laboratory, meanwhile, begun daily CO2 measurements in 1974 and has maintained a complementary, independent measurement record ever since.
The Independent
26 minutes ago
- The Independent
How AI could help stop the next pandemic before it starts
Could artificial intelligence tools be used to stop the next pandemic before it starts? During the Covid pandemic, new technology developed by researchers at Johns Hopkins and Duke universities didn't exist. But, for the first time, researchers there say they've devised a revolutionary large language modeling tool - the type of generative AI used in ChatGP - to help predict the spread of any infectious disease, such as bird flu, monkeypox, and RSV. That could help save lives and reduce infections. 'Covid-19 elucidated the challenge of predicting disease spread due to the interplay of complex factors that were constantly changing,' Johns Hopkins' Lauren Gardner, a modeling expert who created the Covid dashboard that was relied upon by people worldwide during the pandemic, said in a statement. 'When conditions were stable the models were fine. However, when new variants emerged or policies changed, we were terrible at predicting the outcomes because we didn't have the modeling capabilities to include critical types of information,' she added. 'The new tool fills this gap.' Gardner was one of the authors of the study published Thursday in the Nature Computational Science journal. The tool, named PandemicLLM, considers recent infection spikes, new variants, and stringent protective measures. The researchers utilized data that had never been used before in pandemic prediction tools, finding that PandemicLLM could accurately predict disease patterns and hospitalization trends one to three weeks out. The data included rates of cases hospitalizations and vaccines, types of government policies, characteristics of disease variants and their prevalence, and state-level demographics. The model incorporates these elements to predict how they will come together and affect how disease behaves. They retroactively applied PandemicLLM to the Covid pandemic, looking at each state over the course of 19 months. The authors said the tool was particularly successful when the outbreak was in flux. It also outperformed existing state-of-the-art forecasting methods, including the highest performing ones on the Centers for Disease Control and Prevention's CovidHub. 'Traditionally we use the past to predict the future,' author Hao 'Frank' Yang, a Johns Hopkins assistant professor of civil and systems engineering, said. 'But that doesn't give the model sufficient information to understand and predict what's happening. Instead, this framework uses new types of real-time information.' Going forward, they are looking at how large language models can replicate the ways individuals make decisions about their health. They hope that such a model would help officials to design safer and more effective policies. More than a million Americans have died from Covid. It's not a matter of if there will be a next pandemic, but when. Right now, the U.S. is dealing with the spread of H5N1 bird flu, RSV, HMPV, pertussis, and measles, among other health concerns. Vaccination rates for measles have plunged since the pandemic, and general vaccine hesitancy has increased. That has resulted in fears that the nation could see decades of health progress reversed. Furthermore, U.S. health officials have acted to separate from global efforts to respond to pandemics, withdrawing from the World Health Organization earlier this year. Last month, they limited access to Covid vaccines for certain groups. 'We know from Covid-19 that we need better tools so that we can inform more effective policies,' Gardner said. 'There will be another pandemic, and these types of frameworks will be crucial for supporting public health response.'
