
Novo Nordisk shares plunge 23% after Wegovy maker names new CEO, cuts full-year guidance
The company said the lower outlook was driven by weaker second-half U.S. sales growth forecasts for its Wegovy weight loss drug and Ozempic diabetes treatment.
The company also named Maziar Mike Doustdar as its new CEO after the surprise ousting of Lars Fruergaard Jørgensen in May.
Shares fell as much as 26% before paring losses slightly.
Medical bottles and a syringe are seen with the Novo Nordisk logo displayed on a screen in the background.
Nurphoto | Nurphoto | Getty Images
Danish pharmaceutical giant Novo Nordisk on Tuesday named its new CEO while simultaneously slashing its full-year guidance, citing weaker growth expectations for its blockbuster Wegovy obesity drug in the key U.S. market.
The drug maker said company veteran Maziar Mike Doustdar would take over as president and CEO following the surprise ousting in May of Lars Fruergaard Jørgensen. The appointment is effective Aug. 7.
Shares fell as much as 26% before paring losses slightly to close down 23% by 4:30 p.m. London time (11:26 a.m. ET).
The company said it now expects full-year sales growth of 8% to 14% at constant exchange rates, down from a prior target of 13% to 21%.
It expects annual operating profit growth of 10% to 16% versus the previously estimated target of 16% to 24%, also at constant exchange rates.
Novo Nordisk said Tuesday that the lower outlook was driven by weaker second-half U.S. sales growth forecasts for its Wegovy weight-loss drug and Ozempic diabetes treatment.
"For Wegovy in the US, the sales outlook reflects the persistent use of compounded GLP-1s, slower-than-expected market expansion and competition," it added in a statement.
Novo Nordisk.
It comes after the company previously downgraded its 2025 outlook in May, as it reported lower-than-expected first-quarter sales. The company is due to report its full second-quarter sales on Aug. 6.
Doustdar, who joined Novo Nordisk in 1992, has held several executive functions across Europe and Asia, serving most recently as executive vice president of international operations.
In a statement accompanying the announcement, chairman Helge Lund described Mike Doustdar as "the best person to lead Novo Nordisk through its next growth phase."
"I come to this role with a sense of urgency, a laser focus on high performance, and a fierce determination for Novo Nordisk to aim higher than it's ever done, and to deliver to many more patients the innovation they need," Doustdar added.
The Copenhagen-headquartered pharma giant has been battling softer U.S. Wegovy sales as competition from compounded drug makers ramped up in the wake of a Food and Drug Administration drug shortage ruling.
Its share price has shed over 42% this year.
It nevertheless previously said that it expected those pressures to ease in the second half of the year as the availability of copycat drugs was phased out.
Meantime, the firm has struggled to shake negative sentiment following a series of disappointing trial results for its next-generation obesity drug candidate CagriSema amid increased market competition.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Forbes
28 minutes ago
- Forbes
Powerball Jackpot Hits $426 Million—Here's How Much the Winner Could Take Home After Taxes
The Powerball jackpot ticked up to $426 million after no winners were drawn Saturday night, but a lucky winner or winners would take home substantially less after paying federal and state taxes on their winnings. Winners from Monday's upcoming drawing could get either $426 million in installments or a lump sum of $193.5 million, but that would get slashed significantly after taxes. Getty Images No tickets were sold matching all of Saturday's numbers (6, 18, 34, 35, 36, and Powerball number 2), raising the jackpot again for Monday's upcoming drawing. If a winner is drawn Monday, they will have the option of either accepting the $426 million prize spread out over 30 annualized payments, or take the lump sum of $193.5 million, which is the more popular option for winners. However, a federal withholding tax of 24% is applied to that jackpot, bringing the winnings down to $323.7 million, or $147 million for the lump sum. The winnings are then taxed based on the winners income—which could rise as high as 37% for Americans in the highest tax bracket, bringing the final winnings for the lump sum down to $121.9 million. State taxes then reduce this jackpot even further, with New York charging the highest rate at 10.9%, though some states, including California, Florida and Texas, do not tax winnings. The next drawing is scheduled for Monday night at 10:59 p.m. EDT. If no winner is drawn Monday, the next drawings will take place Wednesday and Saturday. Key Background The odds for winning the Powerball jackpot are 1 in 292.2 million, according to the lottery organizers. The odds of winning the $1 million prize (with a ticket matching five numbers without the Powerball number) are 1 in 11.6 million. Big Number $526 million. That's how much a lucky winner in California got after purchasing a winning ticket in March. Because that player won in the Golden State, they did not have to pay state taxes on those winnings.


CNBC
an hour ago
- CNBC
Earnings playbook: Disney and Advanced Micro Devices lead another busy week of reports
The busiest week of earnings has passed, but there are still dozens of key reports still to come that could shake up Wall Street. About 120 S & P 500 companies are scheduled to post their latest earnings. Among them are Disney , Advanced Micro Devices and Dow Jones Industrial Average member Pfizer . Those come after investors last week got quarterly reports from megacap names including Microsoft , Apple , Amazon and Meta Platforms . Roughly two-thirds of the companies in the S & P 500 index have posted quarterly results, with more than 82% exceeding earnings expectations, according to FactSet. Take a look at CNBC Pro's breakdown of what to expect in this week's key reports. All times are ET. Tuesday Pfizer is set to report earnings before the bell. A call is scheduled for 10 a.m. Last quarter: PFE topped expectations as it expanded cost-cutting efforts . This quarter: Analysts expect the pharmaceutical giant to report a slight year-over-year earnings decline, according to LSEG. What to watch: Investors will look for guidance around President Donald Trump's push to lower drug prices — and how that could affect Pfizer's future earnings. The earnings call will likely focus on "RFK Jr and possible risks to vaccines; [and] obesity franchise aspirations and/or other early pipeline opportunities like PFE's next-gen PCV vaccines," BofA analyst Tim Anderson said last month, referring to the Secretary of Health and Human Services. What history shows: Pfizer has a strong track record of exceeding earnings estimates, with the company's bottom line beating expectations 87% of the time, according to Bespoke Investment Group. AMD is set to report earnings after the close, followed by a conference call at 5 p.m. Last quarter: AMD beat on earnings but said it would take a $1.5 billion revenue hit due to restrictions on sales of chips to China. This quarter: Analysts polled by LSEG expect a mixed quarter, with earnings forecast to have dropped nearly 30% year over year, while revenue is anticipated to have grown more than 25%. What to watch: "We see an upside bias for FQ2 (June) results driven by both PC and server" demand, wrote UBS analyst Tim Arcuri on July 28, who rates AMD a buy. "Investors should, however, not expect any quantitative data center GPU commentary for next year as it is probably still too early for AMD to talk about next year other than to say that it feels very good about growth," he added, referring to graphics processing units. What history shows: AMD has fallen after two of the last three earnings releases, including a 6.3% slide after Q4 results came out and an 11% slump following mixed Q3 figures. Super Micro Computer is set to report earnings postmarket. Management's conference call with analysts and institutional investors is slated for 5 p.m. Last quarter: SMCI issued weak guidance, citing " economic uncertainty and tariff impacts ." This quarter: The data center company is expected to post a steep, year-over-year decline in earnings, LSEG data shows. What to watch: JPMorgan analyst Samik Chatterjee placed SMCI on "negative catalyst watch" ahead of these forthcoming earnings, noting "upside in relation to AI demand drivers is likely to be offset by margin pressures stemming from an increasingly competitive landscape, driving downside to the premium valuation multiple SMCI shares are currently trading at." What history shows: According to Bespoke, Super Micro only beats earnings estimates 64% of the time. However, the stock averages a 2.3% advance when the company reports its latest financials. Wednesday Disney is set to report earnings before the bell, followed by a call at 8:30 a.m. Last quarter: DIS climbed on a surprise uptick in streaming subscribers . This quarter: Analysts anticipate the theme park and media giant will report year-over-year earnings growth of about 7%, per LSEG. What to watch: Disney shares have struggled recently, losing more than 5% in the past month, while the S & P 500 is up slightly. Can this report put the House of Mouse back on track? What history shows: Disney earnings have topped earnings expectations in seven of the last eight quarters, per Bespoke. Thursday Eli Lilly is set to report earnings premarket, with a call slated for 8:30 a.m. Last quarter: LLY posted a 45% sales surge on strong demand for weight loss drugs. This quarter: Analysts polled by LSEG expect the Indianapolis-based drugmaker to reveal earnings growth of around 40%. What to watch: Investors will look for continued momentum out of Eli Lilly's Mounjaro weight loss drug. Last week, Lilly said Mounjaro has shown similar heart health benefits in a head-to-head trial with diabetes drug Trulicity, also made by Lilly. What history shows: Bespoke data shows Lilly beats Wall Street expectations 66% of the time. However, the stock doesn't perform well on earnings days, averaging a 0.2% decline.


New York Post
2 hours ago
- New York Post
Elon Musk's long history of having a short fuse and burning through friends and relationships: ‘he busts up with everybody'
Become friends with Elon Musk and, likely, the clock will be ticking. Characters as diverse as Silicon Valley tech moguls and Canadian alt-pop singer Grimes have all entered his personal orbit before later screeching out again, usually followed by some degree of scorched earth via social media. There is no greater example than Musk's relationship with now-President Donald Trump. Everyone knew the richest man in the world would fall out with the most powerful, but few predicted it would happen so quickly — just six months after the inauguration. 'He is prone to lash out,' admitted Faiz Siddiqui, author of 'Hubris Maximus: The Shattering of Elon Musk,' to The Post. 'He is insulated and can make his point.' Advertisement Regardless of how sharp the point may be, Musk can shed a friend and walk away unscathed. 15 Elon Musk has been known to bring disagreements to X and to comment publicly. Getty Images 'He has an army, the largest following on X [the social media platform], that will back him.' Advertisement Here then is a sampling of former friends, colleagues and loved ones who once embraced Musk, only to later feel the burn. Larry Page Google co-founder Larry Page and Elon Musk were so chummy Musk routinely crashed at Page's home. Fortune included the pair in a story about 'eight business leaders you didn't know were BFFs.' But things fell apart when Musk hired a top scientist away from Google in 2015. Musk's artificial intelligence company, xAI, paid Ilya Sutskever $1.9 million to head up its new lab. According to 'Musk,' by Walter Isaacson, the poaching ended their friendship. 'Larry felt betrayed and was really mad at me,' Musk told Isaacson in the book. 'He refused to hang out with me anymore.' Advertisement 15 Larry Page of Google fell out with Elon Musk after Musk poached one of his employees. AFP/Getty Images Zack 'Asmongold' Hoyt It's hard to imagine the world's richest man in a childish spat with an online gaming streamer. But that was the situation with Musk and Zack 'Asmongold' Hoyt. Like other professional gamers, Asmongold watched Musk playing 'Path of Exile 2' on a livestream. Following common sentiment, he alleged Musk paid other people to play for him, which is called 'boosting.' Apparently insulted by the allegation, Musk unfollowed Asmongold and removed his blue checkmark from X. In response, Asmongold posted a YouTube video called 'Elon Musk has Lost It.' Advertisement Musk went on to push out private direct messages between them. Forbes summed up the fallout by noting about Musk, 'He may not really have time to beef with Twitch streamers … Yet, here we are.' 15 The gamer Zack 'Asmongold' Hoyt saw his relationship with Elon Musk fizzle after he accused Musk of boosting a computer game. Asmongold/ X Justine Wilson Justine Wilson was married to Musk from 2000 to 2008. She watched him become a billionaire and bore six children (one of whom died tragically at 10 weeks due to Sudden Infant Death Syndrome). She later described herself as a 'starter wife.' Musk, according to Wilson, told her, 'If you were my employee, I would fire you.' After eight years and three sessions of couple's counseling, Musk filed for divorce. During two years of litigation – which Musk said cost him $4 million – she rallied for their house in Bel Air, 10 percent of his Tesla shares, 5 percent of his SpaceX shares, $6 million and a glacier blue Tesla Roadster. But thanks to a prenup, Wilson said, 'I had effectively sold away all my rights as a married person.' She wound up with far less than the billions won by other tech divorcees like Bill Gates' ex Melinda French and Jeff Bezos' firs wife, MacKenzie Scott. While Forbes estimates Wilson's wealth at $18 million, they also estimate she would have $17.3 billion had she received the settlement requested. 15 Elon Musk and Justine Wilson when they were still married to one another. Justine Musk Advertisement 15 Had Elon Musk given ex-wife Justine Wilson what she asked for in their divorce, Wilson would be a billionaire today. AFP via Getty Images Vivian Jenna Wilson Originally name Zavier, Vivian Jenna Wilson was born male, to Musk and Justine, along with a twin sister, in 2004. Responding to Vivian's transgender identity, Musk publicly maintained that his offspring was 'not a girl' and described them as being 'dead' to him. Vivian went to a California court to change their name and distance themselves from their father. 'I no longer live with or wish to be related to my biological father in any way, shape or form,' Vivian stated in the filing. 15 Vivian Jenna Wilson told a California court that she no longer wishes 'to be related to my biological father.' Vivian Jenna Wilson/TikTok Philip Low Advertisement After meeting Elon Musk socially in 2011, neuroscientist Philip Low, who had been a test subject for Stephen Hawking, became fast friends with the Silicon Valley mogul. Soon after, Low launched a company called NeuroVigil, which boasted a non-invasive device for brain monitoring. Musk invested and joined the board. In 2021, according to Politico, Musk – who had his own brain implant company, Neuralink – wanted to resign from the other company's advisory board. Not wanting him to exercise his stock options, which could significantly hurt Neurovigil, Low fired him. He sent an email to Musk, warning, 'Don't f—k with me.' Advertisement According to Politico, Low '[cast Musk] as obsessive, prone to seeking revenge, power hungry and in constant search of dominance.' 15 Philip Low warned Musk 'don't f–k with me' when he started making noise about exiting his brain implant start-up. Martin Eberhard In 2003, Martin Eberhard was one of two co-founders who incorporated Tesla. Elon Musk invested in the company and, one year later, became chairman. Musk was later recognized as a cofounder, following a lawsuit. 'That was a side issue and it got sorted out,' Siddiqui told The Post. The falling out has more to do with Musk 'claiming that he was almost solely responsible for the company.' Advertisement It doesn't help that Musk ousted Eberhard from his CEO post in 2007, according to Business Insider. Musk has since described Eberhard as 'by far the worst person I've ever worked with in my entire career.' In 2009, Eberhard sued Musk for defamation. Though the suit was settled out of court, in Isaacson's Musk bio, Eberhard does marvel, 'This is the richest man in the world beating on someone who can't touch him.' 15 Martin Eberhard wonders why 'the richest man in the world' would be 'beating on someone who can't touch him.' AP Sam Harris Disagreeing with Elon Musk might not be a good way to foster a friendship with him. The neuroscientist Sam Harris discovered this the hard way. Harris and Musk first became acquainted in 2008. They fell out in 2020 when Musk tweeted 'the coronavirus panic is dumb.' Harris has claimed that he asked Musk to 'walk back' from the position. 'There was a question about Musk weighing in on something that he does not have the expertise to weigh in on,' said Siddiqui. 'Is that putting people at risk?' Harris claimed Musk bet $1 million with him that there would be no more than 35,000 COVID-19 cases in America. If the number exceeded 35,000 Harris would be paid $1 million, to go to a charity. If it did not, Musk would get a $10,000 bottle of tequila. Harris obviously won. But did the million materialize? His texts went unanswered. Since then, via X, Musk called Harris 'mentally ill.' 15 Neuroscientist Sam Harris claims that musk lost a $1 million bet to him and did not pay it. YouTube/ Recode Harris said there is 'something seriously wrong with [Musk's] moral compass.' Grimes The singer whose real name is Claire Boucher was romantically involved with Elon Musk from 2018 until 2021. They have three children with unique names: X AE A-XII (aka, X), Exa (aka, Y) and Techno Mechanicus. There have also been suits and countersuits over custody. In February 2025, Grimes posted to X Musk should respond to a 'medical crisis' involving one of their children. When somebody questioned her taking a private situation to social media, she replied, 'If I have to apply public pressure then I guess that's where we're at.' X accompanied Musk when he met with President Trump in the Oval Office. Grimes allegedly posted to X she does 'not approve that in every conceivable way … I am desperate to solve it … But currently I don't know how to do it.' 15 Grimes went to X to ask Elon Musk to respond to a 'medical crisis' involving one of their children. Getty Images Sam Altman In 2015, Musk, Altman and others founded artificial intelligence company OpenAI as a non-profit. It then launched its for-profit arm, ChatGPT. Musk and Altman then fell out over the direction of the company. 'Musk wanted OpenAI to hold onto this idea that it is a non-profit,' said Siddiqui. 'Like that it would be for the good of humanity.' When Musk moved to buy OpenAI, Altman, 40, accused the tech billionaire of being in 'a position of insecurity,' adding 'I feel bad for the guy.' He also recently told The Post: 'Elon busts up with everybody, that's what he does,' the 40-year-old golden boy behind ChatGPT told The Post. Musk has taken to referring to Altman as 'Scam Altman.' 15 X, standing in front of Elon Musk, is his child who accompanied him to the White House. Getty Images 15 Regarding his former partner Elon Musk, Sam Altman said, 'I feel bad for the guy.' REUTERS Jack Dorsey Dorsey co-founded micro-blogging site Twitter, which Musk eventually bought and re-named X. In 2022 as the deal was about to go through, Dorsey went so far to say he had faith in Musk's 'mission to extend the light of consciousness.' But once in place, Musk made job cuts, changes in policy and the name change. By 2023, Dorsey was saying Twitter 'went south' after his purchase. 15 Twitter cofounder Jack Dorsey claimed that the site 'went south' after Elon Musk took it over. Getty Images Peter Thiel Peter Thiel and Elon Musk have known each other long enough for their relationship to be complicated. In 2000, they combined their respective banking companies to create PayPal. By 2025, it's been a bit of a roller coaster. According to Thiel biography 'The Contrarian,' the two men realized their differences early on. Soon after the merger, Musk crashed his million dollar McLaren while driving Thiel to a meeting. Thiel, according to the book's author, saw Musk as reckless. Musk viewed Thiel as profit driven. Following the merge, while Musk was on his honeymoon, Thiel and his loyalists pushed Musk out of his CEO spot. But the grudge didn't hold. After all, when Musk's SpaceX was going through choppy times in 2008, Thiel provided a $20 million investment that set the company right — and its rocket entered orbit on its next attempt. Though they have called one another unflattering names – according to Business Insider, Musk regards Thiel as 'a sociopath' and Thiel views Musk as 'a fraud' – Siddiqui sees common ground. 'I think philosophically they are largely aligned,' he said. 'In the political arena, they have advocated for a lot of the same policies.' 15 Peter Thiel is said to view Musk as 'a fraud' while Musk is said to view Thiel as a 'sociopath.' AP Vernon Unsworth Sometimes two people try to do the right thing and it goes terribly sideways. Such was the case when Elon Musk and British caver Vernon Unsworth pitched in to save 12 boys trapped in a waterlogged Thai cave system for 15 days. Musk sent engineers from Tesla and a mini submarine to the site. Unsworth took a more traditional approach, finding skilled cave divers and dispatching them to where the boys – members of a Thai soccer team – were trapped. Musk's vessel never got used and Unsworth dubbed it a PR stunt, suggesting that he 'stick his submarine where it hurts.' Musk entertained his 30 million followers on X by dubbing the diver 'pedo guy' in a since deleted tweet. 15 Vernon Unsworth, who helped save the Thai kids trapped in a cave, sued Elon Musk for defamation. The legal action was unsuccessful. AP Unsworth sued for defamation Musk insisted that, in his native South Africa, 'pedo guy' is a common phrase. The kids were saved, Musk was found not guilty of defamation. Musk's lawyer stated the obvious in his summing up: 'In arguments, you insult people.'