
Karolinska Development's portfolio company Umecrine Cognition resumes patient inclusion in its Phase 1b/2a clinical study
Umecrine Cognition is developing a new class of drugs to alleviate cognitive symptoms caused by liver disease. The company's most advanced drug candidate, golexanolone, is currently being evaluated in a randomized, double-blind, placebo-controlled phase 1b/2a clinical study in patients with primary biliary cholangitis (PBC) who experience clinically significant fatigue and cognitive symptoms.
Advertisement
Karolinska Development's ownership in Umecrine Cognition amounts to 73%.
For further information, please contact:
Viktor Drvota, CEO, Karolinska Development AB
Phone: +46 73 982 52 02, e-mail: [email protected]
Johan Dighed, General Counsel and Deputy CEO, Karolinska Development AB
Phone: +46 70 207 48 26, e-mail: [email protected]
TO THE EDITORS
About Karolinska Development AB
Karolinska Development AB (Nasdaq Stockholm: KDEV) is a Nordic life sciences investment company. The company focuses on identifying breakthrough medical innovations in the Nordic region that are developed by entrepreneurs and leadership teams. The company invests in the creation and growth of companies that advance these assets into commercial products that are designed to make a difference to patient's lives while providing an attractive return on investment to shareholders.
Karolinska Development has access to world-class medical innovations at the Karolinska Institutet and other leading universities and research institutes in the Nordic region. The company aims to build companies around scientists who are leaders in their fields, supported by experienced management teams and advisers, and co-funded by specialist international investors, to provide the greatest chance of success.
Karolinska Development has a portfolio of eleven companies targeting opportunities in innovative treatment for life-threatening or serious debilitating diseases.
The company is led by an entrepreneurial team of investment professionals with a proven track record as company builders and with access to a strong global network.
For more information, please visit www.karolinskadevelopment.com.
Attachment
KD Umecrine Cognition resumes eng
Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles

Politico
an hour ago
- Politico
Putin got a warm Trump meeting. Europe is afraid Zelenskyy won't.
While publicly Europe and Ukraine have appeared upbeat, privately officials were wary of Putin's red carpet welcome back to the West, where he secured the veneer of global legitimacy without making the kind of gestures toward peace the U.S., Europe and Ukraine have sought. 'Worries have been there all the way this year, and yesterday's meeting did not really help,' a European official said. Trump's position on the war has yo-yoed in recent weeks. While he had for months blamed Ukraine for the conflict, he had been more critical of Putin and Russia in the lead-up to the summit. He even said Putin would face 'severe consequences,' if he did not agree to stop the war after Friday's gathering. But after several hours of meetings with Putin in Alaska, Trump backtracked on a demand for an immediate ceasefire, again said it would be up to Ukraine to end the fighting and advised Kyiv to 'take the deal,' without specifying what Putin had suggested. Trump said after the summit that he negotiated with Putin over land swaps but declined to provide more details. The White House didn't immediately respond to a request for comment. French President Emmanuel Macron and U.K. Prime Minister Keir Starmer on Sunday will lead a teleconference among the 'coalition of the willing' — countries that have indicated they will provide troops and other support to Ukraine at the end of the war, according to a European official. Ahead of the summit, Trump said he supported some American role in providing security guarantees — some form of assurance or support from Washington to deter Russia from attacking again after a peace deal is agreed. Nordic and Baltic leaders welcomed those commitments again after Trump spoke with European officials late Friday. While Trump did much more than usual to consult with Europe in the lead-up to the summit with Putin and after, the frequent contact does not seem to have yielded tangible results. European officials are relieved that Trump did not agree to a deal with Putin but disappointed that the threat of steep secondary tariffs targeting third countries buying Russian oil was tabled. 'They want to try to influence the negotiation process as much as possible, because they know Trump really wants to do it this way, and they don't want to leave the initiative to Putin,' said Giuseppe Spatafora, a former NATO official who is now a research analyst at the EU Institute for Security Studies. 'In general, the Europeans talk much more often to Trump than during the first 100 days, which is good. They have influence. But it's limited.' Zelenskyy's last visit to the Oval Office in February quickly went off the rails when Vice President JD Vance and later Trump both lectured him for not being grateful enough for American support and overplaying what they said was a weak diplomatic position. Zelenskyy's decision to wear a black polo, black pants and boots rather than a suit further soured the atmosphere. But Trump and Zelenskyy have been on better terms in recent meetings, as Kyiv's allies sought to improve the relationship and Trump's frustration with Putin mounted.


New York Post
3 hours ago
- New York Post
The ‘Nordic diet' can help you lose weight and prevent heart attacks — stock up on these foods
Forget the Mediterranean — the land of snow and salmon is serving up a fresh way to eat that gives your heart a healthy boost. A growing body of research suggests the Nordic diet can help trim your waist, tame your cholesterol levels and keep your blood pressure in check. That could be a game-changer in the fight against cardiovascular disease, which kills an American every 34 seconds. 4 The Nordic diet is packed with fiber, fatty fish and cold-weather produce. Getty Images This northern European way of eating leans heavily on whole foods that retain their natural nutrients, in sharp contrast to the US food supply, where up to 70% is ultraprocessed. It revolves around seasonal, locally sourced ingredients found across Nordic nations like Denmark, Finland, Iceland, Norway and Sweden. '[The Vikings] were limited to the foods available to them at the time,' Lauren Harris-Pincus, a registered dietitian, told Fox News. 'Their diet focused on clean, sustainable foods, which is why we are discussing its health benefits today.' Like the Mediterranean diet — long hailed for its heart-healthy power — the Nordic style is plant-forward, high in fiber and packed with seafood. 4 Fatty fish are excellent sources of omega-3 fatty acids, which are linked to reduced risk of heart disease. artemidovna – But while the Greeks rely on olive oil, the northern approach leans on rapeseed (or canola) oil, another heart-friendly monounsaturated fat, according to Harvard Health. Rapeseed oil is also a source of alpha-linolenic acid, a plant-based omega-3 fatty acid similar to the kind found in fatty fish like salmon, mackerel, sardines and herring — all staples of the Nordic kitchen. Followers typically eat two to three servings of these fish each week. The omega-3s delivered by both the oil and fish have been shown to reduce the risk of heart rhythm issues, slow plaque buildup in arteries and lower fat levels in the blood, key factors in protecting cardiovascular health. The Nordic diet also emphasizes low-fat dairy, such as yogurt, and incorporates eggs and poultry in moderation. Red and processed meats, on the other hand, rarely make it onto the plate. 4 Root vegetables are loaded with vitamins, minerals, antioxidants and fiber. Viktor Iden – Whole grains such as oats, barley and rye are another cornerstone in this eating pattern. These fiber-rich 'complex' carbs digest slowly, helping to curb cravings and keep blood sugar steady — unlike refined grains in processed staples like white bread. Cold-weather veggies like turnips, carrots, parsnips, cabbage and cauliflower are also featured prominently. They're packed with fiber and nutrients that have been shown to help lower cholesterol and blood pressure. Berries like blueberries, strawberries, cranberries and lingonberries play a starring role, too. Rich in antioxidants called anthocyanins, these fruits help keep arteries flexible and may also lower blood pressure. Unlike many American eating habits, the Nordic diet also goes easy on alcohol and avoids foods high in added sugar and sodium. By avoiding processed junk, saturated fats and high-cholesterol meats while loading up on fiber-rich whole foods, studies suggest the Nordic diet can lead to significant weight loss — a major win for heart health. 4 Every year, about 805,000 people in the US have a heart attack. Pixel-Shot – In one study, people who followed the Nordic diet for just six weeks lost 4% of their body weight — significantly more than those eating a standard western diet. In another trial, people with obesity who stuck to it for six months dropped about 10 pounds — roughly triple the weight loss seen in a typical diet group. And it's not just about the scale. In a 2022 analysis, researchers found that the Nordic diet helped lower cholesterol and blood sugar levels independent of weight loss. 'The group that had been on the Nordic diet for six months became significantly healthier, with lower cholesterol levels, lower overall levels of both saturated and unsaturated fat in the blood, and better regulation of glucose, compared to the control group,' study author Lars Ove Dragsted said in a statement. Other studies have found that the Nordic diet can have a positive impact on blood pressure and inflammation. Taken together, and experts say this cold-climate cuisine could be just what the doctor ordered for your heart. A 2023 review even found that the Nordic diet might reduce the risk of death from cardiovascular disease, the leading cause of death in the US. However, more research is needed to nail down exactly how much. Still, experts say Americans could learn a thing or two from their northern neighbors — especially when it comes to cutting processed meats and sugar-laden snacks. 'People who really like berries, rye bread, and canola oil should go ahead and enjoy a Nordic-style diet rather than waiting 10 years to get more evidence,' advised Dr. Frank Hu, professor of nutrition at the Harvard TH Chan School of Public Health.
Yahoo
a day ago
- Yahoo
Inside information: Aspo to divest its Leipurin business to Lantmännen
Aspo Plc Inside information 15 August 2025 at 11.30 a.m. EEST Inside information: Aspo to divest its Leipurin business to Lantmännen Aspo has today signed an agreement to divest its Leipurin business to Lantmännen at an enterprise value of EUR 63 million. The estimated cash consideration payable at closing is approximately EUR 60 million. The transaction is subject to regulatory approvals. The transaction is expected to be completed in the first quarter of 2026. On Capital Markets Day 14 May 2024, Aspo published its portfolio vision: to form two separate companies, Aspo Compounder (Telko and Leipurin) and Aspo Infra (ESL Shipping), in the coming years. Aspo also communicated that divestment of the businesses is one of the strategic alternatives to be evaluated to maximize shareholder value. The divestment of Leipurin significantly strengthens Aspo's balance sheet and enables future growth investments for the Telko business. The divestment of Leipurin is a major step in executing the communicated vision, along with Telko's already completed M&A activities and ESL Shipping's significant investments in best-in-class vessels. 'The divestment of the Leipurin business is the best way to implement Aspo's strategy and value creation. During the past years, Leipurin has sold its equipment-related businesses, exited its businesses in the east and completed three acquisitions in western markets. We have also clearly improved the performance of Leipurin in recent years and supported the success of our customers. I am very proud of the transformation achieved at Leipurin and the work done by the personnel. As part of Lantmännen, Leipurin will continue to have an excellent framework for systematic and customer-driven growth and development,' says Rolf Jansson, CEO of Aspo Plc. 'The acquisition of Leipurin is part of Lantmännen's strategy to broaden and strengthen the value chain in food ingredients. Together with our existing operations and the new plant-based protein facility currently under construction, we see strong opportunities for growth in both existing and new markets. With Leipurin, we gain valuable expertise in developing innovative products in close collaboration with customers,' says Magnus Kagevik, President and CEO of Lantmännen. In 2024, Leipurin's net sales totaled EUR 133.1 million (2023: EUR 136.1 million), comparable EBITA was EUR 4.9 million (2023: EUR 4.5 million) and invested capital EUR 49.7 million (2023: EUR 46.0 million). Leipurin offers food ingredients and expert services in the bakery, food industry and food service markets in Finland, Sweden and the Baltic countries. Leipurin has approximately 160 employees. According to Lantmännen, Leipurin will operate as a separate business within Lantmännen's Energy Division, which currently includes food ingredients operations, such as plant-based proteins and oat-based ingredients. The sale of the Leipurin business will be implemented as a sale of shares, and it will cover all the companies in the Leipurin segment. Aspo will report the Leipurin business as discontinued operations starting from the third quarter of 2025. Upon completion, Aspo will record a sales gain of approximately EUR 16 million, which has an impact on Aspo's reported result. The transaction does not have an impact on Aspo's guidance for 2025: Aspo Group's comparable EBITA is expected to be EUR 35–45 million in 2025. Aspo Group's comparable EBITA expectation includes the comparable EBITA of the whole Group, including Leipurin business. Lantmännen is an agricultural cooperative and Northern Europe's leader in agriculture, machinery, bioenergy and food products. Lantmännen is owned by 17,000 Swedish farmers and it has 12,000 employees and operations in over 20 countries. The annual turnover of Lantmännen is SEK 70 Plc Rolf Jansson CEOFor additional information, please contact: Rolf Jansson, CEO, Aspo Plc, tel. +358 400 600 264, Nasdaq Helsinki Key media Aspo creates value by owning and developing business operations sustainably and in the long term. Aspo's businesses – ESL Shipping, Telko and Leipurin – enable future-proof, sustainable choices for customers in various industries. Established in 1929, today we are together about 800 experts on land and at sea. While the Nordic region is our core market, we serve our customers with world-class solutions in 18 countries around Europe and parts of Asia. Aspo is listed on Nasdaq Helsinki and is headquartered in Finland. Aspo – Sustainable value creationError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data