
Karolinska Development's portfolio company Umecrine Cognition resumes patient inclusion in its Phase 1b/2a clinical study
STOCKHOLM, SWEDEN – May 26, 2025. Karolinska Development AB (Nasdaq Stockholm: KDEV) today announces that its portfolio company Umecrine Cognition has resumed the inclusion of patients to the clinical phase 1b/2a trial evaluating the drug candidate golexanolone in PBC patients. In March, Umecrine Cognition announced that the study had been halted due to technical issues in the production of capsules used in the study, which, however, had no impact on patient safety.
Umecrine Cognition is developing a new class of drugs to alleviate cognitive symptoms caused by liver disease. The company's most advanced drug candidate, golexanolone, is currently being evaluated in a randomized, double-blind, placebo-controlled phase 1b/2a clinical study in patients with primary biliary cholangitis (PBC) who experience clinically significant fatigue and cognitive symptoms.
Advertisement
Karolinska Development's ownership in Umecrine Cognition amounts to 73%.
For further information, please contact:
Viktor Drvota, CEO, Karolinska Development AB
Phone: +46 73 982 52 02, e-mail: [email protected]
Johan Dighed, General Counsel and Deputy CEO, Karolinska Development AB
Phone: +46 70 207 48 26, e-mail: [email protected]
TO THE EDITORS
About Karolinska Development AB
Karolinska Development AB (Nasdaq Stockholm: KDEV) is a Nordic life sciences investment company. The company focuses on identifying breakthrough medical innovations in the Nordic region that are developed by entrepreneurs and leadership teams. The company invests in the creation and growth of companies that advance these assets into commercial products that are designed to make a difference to patient's lives while providing an attractive return on investment to shareholders.
Karolinska Development has access to world-class medical innovations at the Karolinska Institutet and other leading universities and research institutes in the Nordic region. The company aims to build companies around scientists who are leaders in their fields, supported by experienced management teams and advisers, and co-funded by specialist international investors, to provide the greatest chance of success.
Karolinska Development has a portfolio of eleven companies targeting opportunities in innovative treatment for life-threatening or serious debilitating diseases.
The company is led by an entrepreneurial team of investment professionals with a proven track record as company builders and with access to a strong global network.
For more information, please visit www.karolinskadevelopment.com.
Attachment
KD Umecrine Cognition resumes eng
Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
2 days ago
- Yahoo
Invitation: Sobi's Aspaveli® - 52-week Phase 3 VALIANT data in nephrology
VALIANT Phase 3 data in nephrology after presentation at the ERA congress. STOCKHOLM, June 3, 2025 /PRNewswire/ -- Investors, analysts, and members of the media are invited to a conference call on Thursday, 12 June, at 13:30 CEST, 12:30 GMT, and 08:30 EDT. The call will include a presentation of results and insights from management and Professor Fadi Fakhouri following the European Renal Association (ERA) congress and a Q&A session. The presentation can be followed live here or afterwards on The slides will be made available on before the conference call. To participate in the conference call, please use the following dial-in details: Sweden: +46 8 5051 0031United Kingdom: +44 207 107 06 13United States: +1 631 570 56 13 For other countries, please find the details here. Sobi® Sobi is a global biopharma company unlocking the potential of breakthrough innovations, transforming everyday life for people living with rare diseases. Sobi has approximately 1,900 employees across Europe, North America, the Middle East, Asia and Australia. In 2024, revenue amounted to SEK 26 billion. Sobi's share (STO: SOBI) is listed on Nasdaq Stockholm. More about Sobi at and LinkedIn. Contacts For details on how to contact the Sobi Investor Relations Team, please click here. For Sobi Media contacts, click here. Gerard TobinHead of Investor Relations This information was brought to you by Cision The following files are available for download: Invitation Sobis Aspaveli 52-week data View original content: Sign in to access your portfolio

Miami Herald
2 days ago
- Miami Herald
Nordic Parents Have It Great-But Birth Rates Are Still Falling
Much of the world is facing a birth rate crisis, and Norway is no exception despite implementing many of the policies governments, activists, and experts have touted. Newsweek has broken down why. Many trying to tackle this global issue have called for public health policies and financial plans to help make it easier for couples to have children in society. The financial crisis and its impact on housing, inflation and pay is generally cited a major contributor to people's decisions to delay having children, to have fewer children or not to have them at all. Parental leave and childcare come up just as often, with multiple experts telling Newsweek that improved policies in these areas would be a game-changer. Norway is considered a global leader in parental leave and childcare policies, with the United Nations International Children's Fund (UNICEF) ranking it among the top countries for family-friendly policies. "The Nordic model is characterized by strong institutional support for families with children," Rannveig Kaldager Hart, a senior researcher at the Norwegian Institute of Public Health's Centre for Fertility and Health, told Newsweek. Norway offers parents 12 months of shared paid leave for birth and an additional year each afterward. It also made kindergarten (similar to a U.S. day care) a statutory right for all children 1 year of age or older in 2008, which the government has subsidized to make it possible for "women and men to combine work and family life," as Norway's former Minister of Children, Equality, and Social Inclusion Solveig Horne said at a parental leave event in 2016. And yet, Norway's fertility rate has dropped dramatically from 1.98 children per woman in 2009 to 1.44 children per woman in 2024, according to official figures. The rate for 2023 (1.40) was the lowest-ever recorded fertility rate in the country. Oslo created a Birth Rate Committee to investigate the causes, consequences and possible solutions of Norway's birth rate problem last year. It found that "an important cause is that fewer people are having their first child before age 30" and fewer people have more than two children, Hart, who is also the Committee's chair, said. Professor Katrine Vellesen Løken, from the Norwegian School of Economics, told Newsweek that "one leading hypothesis points to lower rates of couple formation for those in their 20s, which in turn contribute to reduced fertility." "While Norway has eased some financial barriers, that's only part of the picture; other psychological, cultural, and structural factors matter too," said Theodore Cosco, a research fellow at the Oxford Institute of Population Ageing. "Parenting is shaped by many factors, and Norway is beginning to reckon with those beyond just financial support, especially the deeper challenges of parenting itself," he told Newsweek. Indeed, Hart also said that "young adults are more likely to live alone" and "young couples split up more frequently than before." He went on to speak about "intensive parenting," which refers to the modern parenting style in which parents invest time, money and energy into creating successful adults. The expectations of this parenting style "may cause some to postpone or have fewer children than they otherwise would," Hart said. Øystein Kravdal, who was a demography professor at the University of Oslo for almost three decades, said the same. "One may also wonder whether young adults to an increasing extent are being exposed to overwhelming expectations about how 'intensely' one should care for a child to be a responsible parent," he told Newsweek. So does this mean that Norway's progressive parental leave and childcare policies should not be part of other countries' solutions? Cosco does not think Norway's approach should be dismissed globally. "Norway shouldn't be seen as a failure," he said. "Fertility is a complex issue that requires a multi-pronged approach." Kravdal argued that Norway would be worse off without its family-friendly policies. "In the last 15 years, Norway's generous support system has not been weakened. If that had happened, the total fertility rate would likely have been even lower than the current 1.44," he said." Løken agreed, saying: "This uncertainty does not rule out the potential role of family policies in addressing the issue." "Measures that provide families with more financial support or time could, in theory, influence the opportunity costs associated with couple formation and having children," she continued. But she added: "Most studies examining the impact of family policies on fertility find only modest and short-term effects-typically influencing the timing of childbirth rather than the total number of children people have." Løken went on to call for a "more ambitious policy direction" involving "efforts to reduce screen time, enhance community and social engagement opportunities, and shift cultural norms around relationships and fertility, particularly among people in their 20s." In its interim report, the Birth Rate Committee looked at offering additional child allowance for parents younger than 30 years old and better education about the ability to have children and pre-pregnancy help. Related Articles World No. 1 Chess Grandmaster Slams Table After Surprise Defeat: VideoNorway To Randomly Select 100,000 Millennials, Gen Z For Tax CutsChinese Must Remove Stone Lions from the Arctic: ReportsPhoenix Ikner Updates: New Details Emerge on FSU Shooter's Childhood 2025 NEWSWEEK DIGITAL LLC.

Yahoo
2 days ago
- Yahoo
Updated financial Calendar for 2025
Company announcement no. 21In continuation of Nykredit takeover of Spar Nord Bank (company announcement no. 15/2025) the Bank's financial calendar for 2025 is updated. Spar Nord Bank now expects to announce the financial statements on the following dates: Date Event 14th August 2025 Semi-Annual Report 30th October 2025 Quarterly Report – Q3Rune Brandt BørglumCFO Attachment Nr. 21 - Updated financial Calendar for 2025 - UKSign in to access your portfolio