Padres at Cardinals Prediction: Odds, expert picks, starting pitchers, betting trends and stats for July 24
Yu Darvish is slated to take the mound for San Diego against Sonny Gray for St. Louis.
Each of these clubs comes into the series riding a two-game losing streak. The Padres lost for the second straight day to the Marlins in Miami on Wednesday. San Diego's offense was held in check by Sandy Alcantara who allowed just one unearned run over seven innings as the Marlins won 3-2. The Cards lost their second straight to the Rockies in Denver yesterday. St. Louis was held to five hits by Tanner Gordon and a couple of Colorado relievers in a 6-0 loss.
Lets dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Padres at Cardinals
Date: Thursday, July 24, 2025
Time: 7:45PM EST
Site: Busch Stadium
City: St. Louis, MO
Network/Streaming: SDPA, FDSNMW
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Padres at the Cardinals
The latest odds as of Thursday:
Moneyline: Padres (+115), Cardinals (-136)
Spread: Cardinals -1.5
Total: 8.0 runs
Probable starting pitchers for Padres at Cardinals
Pitching matchup for July 24, 2025: Yu Darvish vs. Sonny Gray
Padres: Yu Darvish (0-2, 6.08 ERA)
Last outing: July 19 at Washington - 5.40 ERA, 3 Earned Runs Allowed, 5 Hits Allowed, 1 Walks, and 1 StrikeoutsCardinals: Sonny Gray (9-4, 4.04 ERA)
Last outing: July 19 at Arizona - 21.60 ERA, 8 Earned Runs Allowed, 11 Hits Allowed, 0 Walks, and 5 Strikeouts
Padres: Yu Darvish (0-2, 6.08 ERA)
Last outing: July 19 at Washington - 5.40 ERA, 3 Earned Runs Allowed, 5 Hits Allowed, 1 Walks, and 1 Strikeouts
Cardinals: Sonny Gray (9-4, 4.04 ERA)
Last outing: July 19 at Arizona - 21.60 ERA, 8 Earned Runs Allowed, 11 Hits Allowed, 0 Walks, and 5 Strikeouts
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Top betting trends & insights to know ahead of Padres at Cardinals
The Cardinals are 1-5 in their last 6 games
Manny Machado is 2-19 in 5 games since the All-Star Break
Willson Contreras has hits in 4 of 5 games since the All-Star Break (7-20)
Fernando Tatis Jr. is 2-17 (.118) since the All-Star Break
Nolan Arenado is 7-32 (.219) in July
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for Thursday's game between the Padres and the Cardinals
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursday's game between the Padres and the Cardinals:
Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the San Diego Padres at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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Jay Croucher (@croucherJD)
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