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FDA issues highest alert for tomato recall due to salmonella risk

FDA issues highest alert for tomato recall due to salmonella risk

The Guardian3 days ago

The Food and Drug Administration has upgraded a tomato recall in three states to its most severe warning due to a potential salmonella contamination.
Three weeks ago the agency announced a voluntary recall by Williams Farms Repack LLC of its tomatoes across Georgia, North Carolina and South Carolina. Last week, the FDA upgraded the recall to Class 1, indicating a reasonable probability that the product could 'cause serious adverse health consequences or death'.
The tomatoes were distributed between 23 and 28 April. Although no illnesses have been reported, the FDA has urged consumers to either return the tomatoes for a full refund or discard them.
Salmonella, one of the world's leading causes of foodborne illness, are a group of bacteria that can cause gastrointestinal issues and fever. The bacteria spreads when people eat raw or undercooked foods, and can be transmitted by food handlers who do not wash their hands properly, as well as the surfaces and tools they use in food preparation. It can spread from animals to people, with those most at risk including children younger than five, elderly people and those with immunocompromised systems.
Symptoms of salmonella – including diarrhea, fever and abdominal cramps – typically begin 12 to 72 hours after infection and last up to a week. Most people are able to recover without requiring treatment, but in some cases the illness can be fatal, with the US Centers for Disease Control and Prevention estimating 450 salmonella-related deaths every year.

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Alzheimer's blood test can spot people with early symptoms, study suggests
Alzheimer's blood test can spot people with early symptoms, study suggests

The Guardian

time6 hours ago

  • The Guardian

Alzheimer's blood test can spot people with early symptoms, study suggests

A new blood test for Alzheimer's disease can accurately detect people with early symptoms, research suggests. Experts from the Mayo Clinic in the US have provided further evidence that blood tests can work to accurately diagnose dementia by examining two proteins in blood plasma. The proteins – amyloid beta 42/40 and p-tau217 – are associated with amyloid plaque buildup, which is a hallmark of Alzheimer's disease. Researchers found the blood test was highly accurate, with 95% sensitivity, which means it was 95% accurate in picking up people with memory problems, with very few cases missed. It was also 82% for specificity, which means it was also highly accurate in ruling out people without dementia. The study was carried out on more than 500 people in an outpatient memory clinic, meaning it is real-world data. The blood test has been approved by the Food and Drug Administration regulator in the US. Dr Gregg Day, who led the study in the journal Alzheimer's and Dementia, said the test was as good as more invasive tests in use. 'Our study found that blood testing affirmed the diagnosis of Alzheimer's disease with 95% sensitivity and 82% specificity,' he said. 'When performed in the outpatient clinical setting, this is similar to the accuracy of cerebrospinal fluid biomarkers of the disease and is much more convenient and cost-effective.' Overall, researchers found that p-tau217 levels were higher in patients with Alzheimer's disease versus those without the disease. Day said the next steps in the research were to evaluate blood-based testing in more diverse patient populations and people with early Alzheimer's who showed no cognitive symptoms. Dr Richard Oakley, associate director for research and innovation at the Alzheimer's Society in the UK, said the results 'suggest this test is very accurate' and could be used alongside other tests and observations from a trained health professional. 'This study shows how blood tests are making diagnosis of Alzheimer's disease quicker, easier and more accessible than ever before in a real-world setting,' he added. 'While focused on Alzheimer's disease, the test was evaluated in people with other types of dementias too, showing that it may help with differentiate causes of cognitive decline, though more research in diverse groups of individuals and in community-based setting is still needed. 'Currently diagnosis options in the UK are often slow, expensive and can be invasive, meaning thousands miss out on the benefits one can bring. 'It's great to see blood tests like this approved for clinical use in the US. We hope to see the same in the NHS, which is why we're part of the Blood Biomarker Challenge.' The Blood Biomarker Challenge is a multimillion-pound research programme supported by the Alzheimer's Society, Alzheimer's Research UK and the National Institute for Health and Care Research. Its goal is to bring blood tests for dementia diagnosis to the National Health Service by 2029. Oakley said: 'Blood tests will be critical to accelerate diagnosis and give more people access to the care, support and treatments they desperately need faster than ever before. 'We must see long-term investment in the tools and workforce needed to ensure everyone living with dementia can get an early an accurate diagnosis, which is even more important with disease-modifying treatments on the horizon.' Dr Julia Dudley, head of research at Alzheimer's Research UK, said: 'We urgently need to improve how we diagnose dementia and it's great to see international research working towards this goal. 'Blood tests in this study look at p-tau217 and amyloid beta 42/40 and showed the tests offered high accuracy in confirming Alzheimer's disease. 'This study adds to the growing evidence that blood tests can detect the diseases that cause dementia in people with early memory and thinking problems. 'An important point to consider is that people taking part in research don't always reflect the full diversity of those affected by dementia, who might have additional conditions or other characteristics. 'That is why work is needed to understand whether these blood tests work in a real-world setting. 'In the UK, studies like the Blood Biomarker Challenge are helping to build this evidence. The study is testing blood tests, including p-tau217, in thousands of people from sites across the UK. 'This work will be a crucial part of making diagnosis easier and faster, which will bring us closer to a cure.'

Massive 400-pound alligator captured by North Carolina cops and hit with hilarious charges
Massive 400-pound alligator captured by North Carolina cops and hit with hilarious charges

Daily Mail​

time7 hours ago

  • Daily Mail​

Massive 400-pound alligator captured by North Carolina cops and hit with hilarious charges

North Carolina police 'arrested' a gigantic alligator and hit him with hilarious charges for crossing the road. Onslow County Sheriff's deputies along with officers from the NC Wildlife Resources Commission captured the massive beast on May 28 on Old 30 Road. '[Officials] wrangled this prehistoric perp off the pavement today after he was caught loitering near the double yellow line,' the sheriff's office said. Deputies decided to have some fun announcing their impressive catch and released a statement playfully claiming the gator had 'scaly intentions' and was charged with a crime. 'Witnesses say he was just chilling and snapping, clearly ignoring the "no loitering or lounging on roadways" sign,' said the sheriff's office. The reptile was named 'Pepe the Gator' and measured up at 400 pounds and almost 10 feet-long. The sheriff's office jokingly said, '[Pepe] has been cited for Suspicion of Being a Dinosaur Without Proper Papers, Public Loitering with Intent to Sunbathe, and Obstructing Traffic.' 'Deputies reported no injuries, unless you count his pride when the gator refused to be cuffed. 'We're told the gator has been safely relocated — and no, he didn't get to ride shotgun.' The cops also posed for some hilarious photos with Pepe, including one image of a deputy standing behind the beast with his thumb. Another photo showed three deputies sitting on the gator while they restrained him after they covered his with a towel and taped his mouth shut. Community members loved the cheeky post, commenting that they loved seeing the deputies have fun, but thought Pepe's charges were unfair. 'I'm so weak the one on the glasses is having the time of his life,' one person said. 'Y'all are brave riding the bronco-gator,' said another. '#FreePepe my homie did nothing wrong,' a third person said. 'Had he just called Uber instead of trying to walk, he wouldn't be in this mess,' added a fourth. A representative from the Onslow County Sheriff's office told PEOPLE that Pepe was was transported safely to Camp Geiger, a Marine Corps base in Jacksonville. The sheriff's office believed that Pepe had traveled at least three miles from the nearest body of water and needed some help getting to safety in case he hurt himself or injured anyone. According to NC Wildlife, male alligators in the Tar Heel state can reach up to 13 feet and weight up to 500 pounds or more. They are common in freshwater areas and the largest populations live in the coastal counties of Brunswick, New Hanover, Craven, Columbus, Onslow and Pender.

8 now arrested in North Carolina house party shootings and more attempted-murder charges are filed
8 now arrested in North Carolina house party shootings and more attempted-murder charges are filed

The Independent

time13 hours ago

  • The Independent

8 now arrested in North Carolina house party shootings and more attempted-murder charges are filed

Eight people have now been arrested and charged in connection with last weekend's shootings at a western North Carolina house party where a barrage of gunfire ended with one person dead and 11 others injured, authorities said. Five defendants whose arrests were announced Thursday or early Friday by the Catawba County Sheriff's Office made court appearances Friday. Four of the five were facing one count each of attempted first-degree murder. A judge ordered two of those four to remain in jail without bond, according to the Catawba County Clerk of Court's office. But late Friday, the sheriff's office announced that 10 additional counts of attempted first-degree murder had been filed against each of the four who already faced one similar count. All four were jailed pending scheduled court appearances early next week, according to an office press release. A prosecutor handling the defendants' appearances Friday said in court that the shootings were gang-related, and the sheriff's office agreed, news outlets reported. 'Gang motives were a part of this tragedy,' sheriff's Maj. Aaron Turk told WSOC-TV. 'We are still unraveling that as part of our larger investigation.' Investigators have said both adults and young people were among the scores of attendees at the house party in a residential neighborhood roughly 55 miles (88.5 kilometers) northwest of Charlotte. Another defendant arrested earlier in the week also is charged with one count of attempted first-degree murder. The two others were charged with helping underage youth possess alcoholic beverages — the sheriff's office identified them as planning and promoting the house party. Authorities have said over 80 shots were fired shortly after midnight June 1 in a crime scene that spanned several properties. The shootings began with gunfire coming from an elevated area in a yard neighboring the house, the Catawba sheriff's office has said, with shots later around the home, the home's front yard and by a road. Shawn Patrick Hood, 58, of Lenoir, was killed. He was the oldest of the victims, who ranged in age from as young as 16, the sheriff's office said. Most of the people injured were shot, Turk has said. As of Friday, no one had been specifically charged for Hood's death. Turk told reporters this week that investigators needed to account for every shot that had been fired at partygoers 'before we can discern who might be responsible for the homicide.' FBI agents had been at the crime scene this week examining bullet trajectories.

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