
Mollisonia symmetrica: Fossil suggests spiders originated in the sea
What did scientists discover?
An international team of experts led by the University of Arizona in the US, decided to take a closer look at a half-a-billion-year-old marine fossil of an extinct animal called Mollisonia symmetrica.They undertook a detailed analysis of its well-preserved features including its brain and central nervous system. Until now, the creature was thought to be an ancient member of a specific group of arthropods known as chelicerates, which lived during the Cambrian period (around 500 million years ago) and are ancestors to modern-day horseshoe crabs. However, to the team's surprise, they found that the brain structure of the Mollisonia symmetrica was not similar to that of horseshoe crabs, as would be expected.Instead, it had more in common with modern spiders and their relatives.This led scientists to suggest that the first spiders were marine, originating in the ocean.
Professor Nicholas Strausfield, the lead author of the study, said that many questions still remain over how arachnids evolved and moved from the sea to the land."It is still vigorously debated where and when arachnids first appeared and whether these were marine or semi-aquatic like horseshoe crabs."He also suggested what these ancient spiders could have fed on when they first moved on to the land. "We might imagine that a Mollisonia-like arachnid also became adapted to terrestrial life making early insects and millipedes their daily diet," Professor Strausfield added.The team now think that Mollisonia symmetrica could be the ancient ancestor of a wide range of arachnids including spiders and scorpions.
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Telegraph
5 hours ago
- Telegraph
Trump's new missile that could halt a Chinese invasion of Taiwan
A frantic arms race between the US and China is underway in the Pacific while the fate of Taiwan hangs in the balance. Washington and its allies are trying to stay ahead of Chinese capabilities, shaking Beijing off-balance as it considers whether it can launch a successful invasion of Taiwan. At the heart of the US strategy is a new technology that has the ability to inflict devastating losses on the Chinese navy: precision strike missiles (PrSMs, pronounced 'prisms'). The missile has just been tested in Australia, where it struck a target more than 190 miles away, marking the first time the Lockheed Martin-manufactured weapon has been used by a US ally. It can be fired with either American-made Himars or British MLRS artillery systems: missile launchers that were recently used by Ukraine to launch counter-offensives on invading Russian forces and strike deep inside enemy territory, blunting Moscow's advances. Game-changing firepower To date, those launchers have been used with Atacms missiles, which have been in service for more than three decades with a top range of some 190 miles. But PrSMs reportedly have a range of more than 300 miles, with the potential for this to improve in future variants. And at the recent test flight in Australia, the missile reached speeds of 4,000kmph, beating the Atacms by some 300kmph. Each launch pod will be able to hold two of the precision missiles, compared to just a single Atacm, according to Alex Miller, the US Army's chief technology officer. It is also said to be less susceptible to jamming. The PrSMs combine those next-generation improvements with the advantages of the Himars and MLRS systems, which are quick, agile and relatively easy to disguise – and could wreak havoc on Chinese ships attempting an invasion. Brad Bowman, a senior director at the Foundation for Defence of Democracies, said: 'It really creates a challenge for our adversaries, because where that system is now, it may not be there in 30 seconds or five minutes… That's a real detection and targeting dilemma.' Both the US and China are ramping up their military capabilities in the Pacific and particularly around Taiwan, which Beijing regards as part of its territory even though it has effectively been independent since the 1940s. Taiwan under threat Earlier this year, Xi Jinping, the Chinese premier, said 'reunification' with China was inevitable, and that those on either side of the Taiwan Strait were 'one family'. China has regularly threatened Taiwan with fighter jet and warship incursions, but has always stopped short of a direct confrontation. At a security conference in May, Pete Hegseth, the US defence secretary, warned that a Chinese invasion of Taiwan 'could be imminent'. The stakes couldn't be higher, for both sides. If the US's military capabilities are outstripped by China, it would prove fatal to Taiwan, which relies on Washington to provide a credible deterrent. And if the island nation falls, it means the loss of a key strategic buffer against Beijing expansionism. But failing to take the island would inflict a stunning blow on China, and almost certainly lead to the fall of Xi's regime. 'There's always a constant battle with both sides to try to respond to whatever advances the other side has,' said Doug Bandow, a senior fellow with the Cato Institute. 'But I'd say these [PrSMs] have the potential for dramatically increasing the risk factor for a Chinese fleet. So that's substantial.' China's military will be only too aware of the damage Ukraine has managed to inflict on Russia using Himars since they were first provided by the US in June 2022, and will be warily eyeing the upgraded precision missiles. Taiwan already has 11 Himars from previous arms sales with the US, and it is expected to receive more in 2026. Mr Bandow said the PrSMs will have inflicted an important psychological blow on China without any shots even being fired, and could convince its leadership to delay its imperial ambitions. 'The most important advantage of a weapons advance like this is it simply encourages the Chinese to say, 'No… we don't have to do it now',' he told The Telegraph. 'In my view the best chance of getting through this is to simply have that happen a lot. And hopefully we can get to a point, whatever that point is, where everyone agrees war is really stupid and this won't happen.' Real damage could be inflicted on the Chinese fleet, both in ports and moving out to a potential invasion, if PRsMs are deployed throughout Taiwan and the rest of the first island chain, which includes Japan, Indonesia and parts of the Philippines. Australia aligns with US Elsewhere in the Pacific, Australia signed a $310m deal with the US to join the missile programme in June. 'This is all about extending deterrence in the Indo-Pacific, all about signalling to any potential adversary that pain can be inflicted,' Pat Conroy, Australia's defence industry minister, said at the test flight this month. But China is also moving quickly to innovate, and earlier this year appeared to be constructing D-Day style barges for an invasion that would allow it to bypass rocky or soft beaches unsuitable for tanks, providing multiple fronts for an invasion. Some experts are concerned the US is too slow to procure PrSMs. The Pentagon's recent funding request to Congress shows the army intends to buy 44 of the missiles from Lockheed Martin. 'There's very rarely a decisive game changer by itself… but this is a key capability for the United States and our allies to have,' Mr Bowman said. 'That is the ability to sink Chinese naval vessels in large quantities from ground-based mobile platforms. That's why I think we need a whole lot of them, fast.'


The Sun
5 hours ago
- The Sun
‘Game-changing' Alzheimer's drug could STOP disease in its tracks – as the ‘most powerful weapon' against condition yet
A NEW "game-changing" drug could stop the progression of Alzheimer's disease, early trials suggest. Scientists say the treatment - called trontinemab - could be the most powerful weapon yet against dementia, as they look into giving the drug to people with no symptoms in the hopes of preventing disease. 1 Phase two trial results for trontinemab were presented at he Alzheimer's Association International Conference in Toronto. Researchers said the drug seemed to clear plaques - the abnormal build-up of proteins around brain cells that cause damage and disrupt function - quicker than other drugs licensed to treat Alzheimer's. Trontinemab cleared out plaques and eliminated visible signs of the the disease within 28 weeks for nine out of 10 patients. Drug-maker Roche is now conducting another trial to see if plaque clearance also improves patients' memory. The 18-month study includes 1,600 people, the Telegraph reported. Separate research will examine whether the drug could be given to people without any signs of dementia, just as statins are used to ward off heart disease. Experts hope the drug could stop patients from developing dementia symptoms at all, if it is given early enough. They described the findings so far as 'very promising', suggesting that the drug was much more powerful than existing ones while leading to fewer side effects - as it was able to clear plaques better within seven months that other drugs can in 18 months. Roche's chief medical officer Levi Garraway said: 'Alzheimer's disease represents one of the greatest challenges in healthcare today and tackling it requires early detection and effective therapeutics. 'Trontinemab is designed to target a key driver of Alzheimer's disease biology more effectively in the brain. "Combining new treatment avenues with advanced diagnostics may enable earlier and potentially more effective intervention. "With plans for phase three trials in both early symptomatic and pre-clinical Alzheimer's disease, we are advancing science with the goal of delaying - and ultimately preventing - progression of this devastating condition.' Prof Sir John Hardy, the chairman of molecular biology of neurological disease at University College London's Institute of Neurology told the Telegraph trontinemab could be 'game-changing'. The scientist, who was the first to identify the role of amyloid plaques in Alzeheimer's, said: 'This is absolutely great news. "It sucks the plaque out of the brain really quickly, much faster than we have seen with lecanemab or donanemab.' Both are Alzheimer's drugs approved for used in the UK, which target amyloid proteins in the brain to slow disease progression. However, neither treatment is offered on the NHS, as the National Institute for Health and Care Excellence (Nice) deemed them too expensive - in large part because patients need frequent scans to monitor for brain swelling and bleeds. Prof Hardy added: 'There is no doubt [trontinemab] could be game-changing. "We hope that if we can use these drugs to people early, we can halt the progression of disease, even before people have symptoms. "Now we need to see the size of the clinical effect. 'These results show it is much faster and safer than previous drugs, which means less monitoring. "That brings down the cost significantly, it means fewer MRI scans, so that would surely mean it would get Nice approval.' Early signs of dementia It's not unusual for your memory to lapse a bit as you get older. But dementia is different from 'just getting old' as it will cause noticeable - rather than gradual - changes to mental abilities and make managing everyday tasks and activities increasingly difficult. The symptoms of dementia may be small to start with, but get worse over time. Below are some examples of possible signs. Memory loss Memory loss is a key sign of dementia. This can include: Forgetting something you were only recently told. You may ask for the same information repeatedly – for example, 'Are the doors locked?' Putting objects in unusual places – for example, putting your house keys in the refrigerator. Being unable to learn new tasks, like how to use a new washing machine. Planning and decision making issues People with dementia can have difficulty with planning and decision making. This can include: Getting very confused when planning or thinking things through. Struggling to stay focused on a single task. Not making informed, careful decisions when dealing with money or looking at risks. Finding it hard to manage regular payments, budgets or monthly bills. Problems with language and understanding In people with dementia, this can manifest as: Having frequent problems finding the right word or regularly referring to objects as 'that thing'. Finding it hard to take part in conversations. Regularly being unable to follow what someone is saying even without distractions. Losing sense of time and place Dementia can cause problems with orientation, including: Losing track of the date, season or the passage of time. Getting lost in a place that is familiar or that should be easy to find your way around – for example, a supermarket. Regularly being unable to follow what someone is saying even without distractions. Problems with vision and perception This can mean having problems making sense of what you see. For example, having difficulty judging distances on stairs, or mistaking reflections or patterns for other objects. Mood and behavioural changes Finally, dementia can also make people act differently or shift their mood. This can mean: Becoming withdrawn and losing interest in work, friends or hobbies. Feeling unusually sad, anxious, frightened or low in confidence. Getting easily upset at home, at work, with friends or in places that usually feel comfortable or familiar. Trials for lecanemab and donanemab showed the drugs helped clear toxic clumps out of the brain and slow nerve damage caused by Alzheimer's by 27 per cent and 35 per cent respectively, over the course of 18 months. But the treatments did present a risk of brain swelling and brain bleeds, meaning patients needed intense monitoring. Trontinemab appears to be safer and cause fewer side effects, with less than five per cent of patients showing abnormal results on their brain scans. All of these cases were quickly resolved, researchers said. The drug - administered by infusion into the bloodstream - also doesn't need to be given a frequently. Upcoming trials will examine the impact of giving the drug to patients once a month for six months, then every three months. Trontinemab has been designed to efficiently bypass the blood-brain barrier, a protective layer of cells that stops harmful substances in the blood stream from attacking the brain and spinal cord. This barrier can make it hard for many drugs to reach the brain. Prof Jonathan Schott, the chief medical officer at Alzheimer's Research UK, told the Telegraph: 'We urgently need a range of treatments for Alzheimer's that are effective and safe for the people affected by this devastating disease. 'Evidence presented at the Alzheimer's Association conference in Toronto on trontinemab is very promising, showing that the drug can effectively and rapidly clear amyloid from the brain, seemingly with very few side effects. 'We now need to see whether these early stage results carry through to later stage clinical trials, which are planned to start later this year, including in the UK. "These trials will show whether the drug is not only safe, but impacts on memory, thinking and quality of life.' He said it was 'exciting' that the drug would now be tested in some people without symptoms under the phase three trials.


The Independent
11 hours ago
- The Independent
Krill catch in Antarctica soars to record following collapse of conservation deal
Trawling near Antarctica for krill — a crustacean central to the diet of whales and a critical buffer to global warming — has surged to a record and is fast approaching a never before reached seasonal catch limit that would trigger the unprecedented early closure of the remote fishery, The Associated Press has learned. The fishing boom follows the failure last year of the U.S., Russia, China and two dozen other governments to approve a new management plan that would have mandated spreading out the area in which krill can be caught and creating a California-sized reserve along the environmentally sensitive Antarctic Peninsula. In the first seven months of the 2024-25 season, krill fishing in Antarctica reached 518,568 tons, about 84% of the 620,000-ton limit that, once reached, will force the fishery to automatically close. In one hot spot, the catch through June 30 was nearly 60% higher than all of last year's haul, according to a report from the Commission for the Conservation of Antarctic Marine Living Resources, or CCAMLR, the international organization that manages the world's southernmost fishery. The report, which has not been publicly released and CCAMLR said contains confidential data, was shared with The AP by someone concerned about overfishing in Antarctica on the condition of anonymity because they were not authorized to release the information. 'The vast majority of the krill take is from an increasingly smaller area,' said Capt. Peter Hammarstedt, campaign director for conservation group Sea Shepherd Global, which this year made its third voyage to Antarctica to document the fishery. 'It's the equivalent of a hunter saying that they're only killing 1% of the U.S.' deer population but leaving out that all of the deer were shot in Rhode Island.' Threat from climate change, advances in fishing Krill is one of the most abundant marine species in the world, with an estimated biomass of 63 million metric tons. But advances in fishing, climate change and growing demand for krill's Omega-3 rich oil – for fishmeal, pet food and human dietary supplements — have increased pressure on the krill stocks. In the 2023-24 season, a fleet of 12 industrial trawlers from mostly Norway and China caught 498,350 tons of krill — until now the largest harvest since CCAMLR began collecting catch data in 1973. AP journalists traveled to the icy waters around Antarctica in 2023 and observed how factory ships trawl in close proximity to whales whose numbers are still recovering from a century of industrial culling that nearly drove them to extinction. Underscoring the competition between humans and whales, three humpback whales were found dead or seriously injured last year in the long, cylindrical nets deployed by the vessels to vacuum up the paper-clip sized crustacean. Officials have been negotiating for years a new management plan that would balance the growing market for krill with calls for greater protection of the Antarctic Peninsula, the continent's northernmost point and an area teeming with whales and, increasingly, tourists. Currently, less than 5% of the Southern Ocean is protected — well behind CCAMLR's target and a United Nations goal to preserve 30% of the world's oceans by 2030. But a tentative deal fell apart at last year's CCAMLR meeting over a last minute proposal by the United Kingdom and Australia for an even lower catch limit than the one agreed to during talks, AP reported last year. China, objecting to the persistent Western demands, then withdrew its support for the marine reserve and refused to renew the existing management system. 'The truth was it was the UK,' Matts Johansen, chief executive of Norway's Aker BioMarine, the world's largest supplier of krill-based products, said at the United Nations Oceans conference in June. 'Just a couple days before the vote, the UK threw another suggestion and that's when the Chinese backed off.' A spokesperson for the UK Foreign Office rejected that characterization and said the British government continues to push for a krill management strategy that better safeguards Antarctic marine species and vulnerable ecosystems. Catch limit restrictions expire In the absence of a deal, restrictions adopted 15 years ago to spread out the catch limit expired, allowing the krill fleet to essentially fish anywhere at any time, including in smaller habitats preferred by whales and other animals such as penguins and seals. Krill aren't just vital to marine ecosystems. Increasingly, researchers are focusing on their role as a bulwark against climate change. One peer-reviewed study last year found that krill remove from the atmosphere and store in the ocean 20 million tons of carbon annually. That's the equivalent of taking off the road 5 million cars every year. CCAMLR declined to comment on the report obtained by the AP. Ship tracking data analyzed by Global Fishing Watch at the request of the AP also showed a higher concentration of trawling. Activity in one popular fishing ground, denoted Sub-Area 48.1, appears to have more than doubled so far this season compared to the entire 2023-2024 season, according to the the U.S.-based group, which supports sustainable fishing. Javier Arata, the executive director the Association of Responsible Krill harvesting companies, whose members are responsible for 95% of the krill taken from Antarctica, said the catch limit that lapsed was always intended as an interim measure. His group supports the creation of marine protected areas in Antarctica. But it rejects waiting for a conservation deal to adopt 'ready-to-go measures' raising the quota, which he said can be much higher. 'The failure to advance management was political, not scientific,' he said. The current fishing levels, although higher than previous limits, remain sustainable and reflect the consensus recommendation of scientists before last year's deal fell apart, Arata added. — This story was supported by funding from the Walton Family Foundation. The AP is solely responsible for all content. __ Contact AP's global investigative team at Investigative@ or