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Here's why belly fat is more common as we age, and 3 ways to prevent it

Here's why belly fat is more common as we age, and 3 ways to prevent it

Yahoo01-05-2025

More people are focused on staying healthy and fit as they grow older — but it's true that it can become more challenging with age.
New research has revealed that cellular changes during the aging process can cause belly fat — and that's exacerbated by stress and sleep issues that contribute to weight gain.
"People often lose muscle and gain body fat as they age — even when their body weight remains the same," study author Qiong (Annabel) Wang, Ph.D., an assistant professor in the Department of Molecular & Cellular Endocrinology at City of Hope, said in a press release.
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Published in the journal Science, the preclinical research involved experiments on mice that were later confirmed with human cells.
Researchers focused on a group of stem cells called adipocyte progenitor cells (APCs) within the fatty tissue responsible for age-related weight gain.
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When they transplanted these cells from mice of various ages into another group of younger mice, they noticed the creation of large numbers of fat cells within the younger mice.
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However, when they transplanted a batch of cells from young mice into old mice, they did not see the same effect.
The results confirmed that older stem cells are more likely to lead to new fat cells, regardless of the age of the host receiving them, the press release noted.
"While most adult stem cells' capacity to grow wanes with age, the opposite holds true with APCs — aging unlocks these cells' power to evolve and spread," said Adolfo Garcia-Ocana, chair of the Department of Molecular & Cellular Endocrinology at City of Hope, in the press release.
Aging also changes these APCs into yet another group of cells called committed preadipocytes, age-specific (CP-As), which actively churn out new fat cells.
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Humans have a "signaling pathway" — a chemical reaction that controls how the body makes cells — called the leukemia inhibitory factor receptor (LIFR), experts said.
"Our research indicates that LIFR plays a crucial role in triggering CP-As to create new fat cells and expand belly fat in older mice," Wang said in the same release.
Despite the effects of aging, there are steps people can take to prevent expanding waistlines, according to Dr. Sajad Zalzala, co-founder and chief medical officer of AgelessRx in Detroit, Michigan.
"As we age, our ability to maintain lean muscle mass decreases, which contributes to metabolic slowdown and increased fat storage, particularly around the abdomen," Zalzala, who was not involved in the City of Hope study, told Fox News Digital.
He recommends starting the day with 20 to 30 grams of protein, which can be found in foods like Greek yogurt, protein shakes and eggs.
Eating protein at the beginning of the day keeps you full longer, stabilizes blood sugar and encourages muscle maintenance, according to the doctor.
"Chronically high cortisol levels, which can be driven by poor sleep or stress, promote fat storage, especially around the waist," Zalzala noted.
People should aim for seven to nine hours of quality sleep per night, according to experts.
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Zalzala also recommends stress-reduction strategies like walking, mindfulness and breathwork, calling them "powerful tools for fat regulation and metabolic health."
"The study reminds us that aging adipose tissue behaves differently — it's more inflammatory and prone to dysfunction," said Zalzala.
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"Minimizing added sugars and highly processed carbs (white bread, pastries, sugary drinks) reduces insulin resistance and fat accumulation, particularly visceral fat that sits deep in the belly."Original article source: Here's why belly fat is more common as we age, and 3 ways to prevent it

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Can adults grow new brain cells?
Can adults grow new brain cells?

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time11 hours ago

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Can adults grow new brain cells?

When you buy through links on our articles, Future and its syndication partners may earn a commission. The developing human brain gains billions of neurons while in the womb, and tacks on some more during childhood. For most of the 20th century, the conventional wisdom was that the brain cells grown before adulthood would be the only ones we would have for the rest of our lives. But over the past few decades, more and more research is challenging that belief. So is it actually possible for adults to grow neurons? While some experts believe there's strong evidence that we can gain brain cells after childhood, others are still skeptical of this notion. The process of creating new brain cells is called neurogenesis. Researchers first observed neurogenesis after birth in lab animals of various ages, including mice, rats and songbirds. In adult mice, they found new neurons growing in parts of the brain collectively called the subventricular zone, an area closely linked with sense of smell, as well as in the hippocampus, a structure that's central to memory. Researchers think that neurogenesis in these brain regions is important for plasticity, or the brain's ability to adapt and change over time. Plasticity underlies the ability to learn and form memories, for instance. In mice, it's clear that lifestyle factors such as living in a stimulating environment and exercising can promote the growth of new neurons. Conversely, in mouse models of diseases like Alzheimer's, neurogenesis is hampered. What's still up for debate is whether these findings extend beyond mice and other lab animals. "Most of our knowledge about adult neurogenesis came from studies in animal models," Hongjun Song, a professor of neuroscience at the University of Pennsylvania Perelman School of Medicine, told Live Science in an email. "Whether such knowledge can be directly translated to human studies is a challenge." That's because many of the studies that have established the existence of adult neurogenesis in animals used methods that aren't possible in human studies, such as injecting radioactive tracer molecules into the brain. These methods enable scientists to visualize if and where new neurons are growing, but the tracers themselves can be toxic. These methods also require dissecting the brain after the animal has been euthanized. "Unfortunately, there is no way to measure neurogenesis in the living person yet," Gerd Kempermann, a professor of genomics of regeneration at the Center for Regenerative Therapies in Dresden, Germany, told Live Science in an email. Related: Is there really a difference between male and female brains? Emerging science is revealing the answer. There are, however, some rare cases in which scientists have been able to apply similar methods to track neurogenesis in humans. For example, the radioactive tracer molecules used in animal neurogenesis studies are also sometimes used by doctors to track tumor growth in patients with brain cancer. While these radioactive tracer molecules are too toxic to give to healthy people, their benefits outweigh their risks in patients who already have cancer. Scientists behind a 1998 study published in the journal Nature Medicine used this approach and analyzed the brains of cancer patients after their deaths. They reported that, in addition to flagging cancer cells, the tracer molecules had marked new neurons in the hippocampus. This finding suggested that humans could grow new neurons well into adulthood, given the patients were 57 to 72 years old. Later, a 2013 study in the journal Cell used a form of radiocarbon dating to look for new neurons in humans. Radiocarbon dating usually determines the age of a sample by comparing the relative proportion of two different forms of carbon, or carbon isotopes, called carbon-14 and carbon-12. But to study neurogenesis in humans, scientists instead looked at carbon-14 concentrations inside the DNA of cells. Their approach took advantage of the fact that there was a spike in carbon-14 levels in the atmosphere caused by nuclear bomb tests in the 1950s and 1960s. People's bodies absorbed this carbon-14 via their diets, and it became incorporated into their DNA. The amount of carbon-14 in a given cell corresponds to the isotope's concentrations in the atmosphere at the time the cell formed, making it possible to roughly pinpoint the "birthday" of that cell — and determine whether it formed after its owner's birth. By analyzing postmortem brain tissue from people ages 19 to 92, this radiocarbon study identified newborn neurons in the adult hippocampus. But while compelling, the study's methods were so complex that the results have never been replicated. That said, there are also more indirect markers of neurogenesis, such as certain proteins that are only present in growing neurons. Using these methods, both Kempermann and other research groups have uncovered additional evidence of newborn neurons in the adult human brain. "There are many different markers that are more or less specific for adult neurogenesis," Kempermann said. "In tissue sections, one can study these markers under the microscope and look for patterns that are consistent with neuronal development." But some researchers aren't convinced by this evidence. Arturo Alvarez-Buylla, a professor of neurological surgery at the University of California, San Francisco, has spent his career studying the growth of new neurons. While he's observed new neurons being formed in children and adolescents, he's found little evidence to support the notion of neurogenesis in adults. Alvarez-Buylla believes there are a number of issues that may lead other researchers to find signs of neurogenesis in adult humans. For example, the chemical markers that some labs use to track new neurons may also show up in other cell types, such as glia, which are cells in the brain that support neurons' function in various ways. This may make it appear that new neurons are growing when they're actually not. He's also skeptical of the use of carbon-14 dating for this purpose, calling it "creative" but arguing that researchers can't confirm that the new cells are neurons, or if there could be other potential reasons for varying carbon-14 levels in cells. But Alvarez-Buylla isn't ruling out the possibility of human adult neurogenesis; he's only saying that — so far — the evidence hasn't convinced him. "I would say that is a rare phenomenon," said Alvarez-Buylla. "If it happens, it's very, very few cells." 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Immigration Research Shows Stephen Miller Wrong About American Science
Immigration Research Shows Stephen Miller Wrong About American Science

Forbes

timea day ago

  • Forbes

Immigration Research Shows Stephen Miller Wrong About American Science

White House Deputy Chief of Staff Stephen Miller attends a press briefing at the White House on ... More February 20, 2025. Miller, the chief architect of the Trump administration's immigration policy, argues that American scientific achievement owes little to immigrants. A significant body of research disputes that contention. (Photo by) Stephen Miller, the chief architect of the Trump administration's immigration policy, said recently that American scientific achievement owes little to immigrants. A significant body of research disputes that contention. Miller's argument and a statement by Vice President JD Vance about the Apollo Program seem designed to justify the administration's restrictions on international students and high-skilled immigrants. On May 31, 2025, in a statement on White House Deputy Chief of Staff Stephen Miller wrote, 'During the middle of the 20th century—when the U.S. achieved unquestioned global scientific dominance—there was net zero migration. From the 20's to the 70's the foreign-born population was cut almost by half while the overall population doubled. (Until Hart-Celler kicked in).' Contrary to the implication of Miller's statement, American science owes a great deal to immigrants in the post-war period. Between 1945 and 1974, 16 of the 30 U.S. winners of the Nobel Prize in physics were immigrants, according to a National Foundation for American Policy analysis. In 1954, the Atomic Energy Act established an award recognizing scientific achievements in atomic energy. Italian-born Enrico Fermi won the first award. Five of the first eight winners of what became the Enrico Fermi Award (named after his death) were immigrants. Four of the nuclear scientists who came to the United States from Europe in the 1930s later received a Nobel Prize for physics: Felix Bloch, born in Switzerland, won it in 1952, Emilio Segre (Italy) in 1959, and Maria Mayer (Poland) and Eugene Wigner (Hungary) won the award in 1963. 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'Truly magical': The 17-year cicada is ready to rock
'Truly magical': The 17-year cicada is ready to rock

Yahoo

timea day ago

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'Truly magical': The 17-year cicada is ready to rock

Woo! Science is a column of science news and newsmakers in Worcester and the region. Got a science news idea? Email Margaret Smith at msmith@ With their bright red eyes and dapper, red-veined wings, the males are truly putting on the ritz, but is it enough to dress to impress? Maybe as Cass Elliot once sang, "Words of love, soft and tender, won't win a girl's heart anymore." Nevertheless, they'll be ready to sing loud, sing proud, and even if humans hear a reedy, frantic cacophony, remember: there's lots of different love languages. We can only be talking about one spectacular insect, and one event: the periodic, 17-year emergence of cicadas. And we as humans are dazzled, delighted, but sometimes confused and maybe a little worried, as we so often are when lots and lots of insects show up all at once. The so-called periodical cicada is emerging now on parts of Cape Cod and the southeastern part of the state, said Tawny Simisky, entomologist with UMass Extension's Landscape, Nursery and Urban Forestry Program. Simisky specializes in insects that may damage trees and shrubs, but not to fear as we shall see, cicadas that depend on trees also give back. "There is a lot of anticipation about the periodical cicadas in Massachusetts," said Simisky. Dubbed "Brood XIV, " or "Brood 14," by means of record-keeping parlance, Simisky said, "These are all cicadas in a given geographic area, expected to emerge at the same time." The female cicada lays her eggs in the stems or twigs of trees, by means of an ovipositor, a sharp organ that can slice a hole in which the female can lay her eggs. And so, for 17 years, the young cicadas move from larval to nymph or adolescent phase, before emerging, ready to shed their juvenile skin, and carefully inflating their newfound, grownup wings. Simisky said, "We have folks reporting them coming up from beneath the ground in Eastern Sandwich, Mass., on May 17." This is when so-called exit holes appear in the ground, small and perfectly dime-sized. Where can you find them? "Some areas on Cape Cod, in Barnstable County, and possibly a much smaller area of Plymouth County," Simisky said. "This past Friday, prior to the long weekend, I went out there, and brought my entire family." Simisky returned with photos, including those of newly-emerged cicadas. If it seems like a curious career, spending most of your existence in the juvenile phase, emerging only for a short time in the hopes of finding a mate and passing on that cicada DNA, it puzzles scientists, too, but from a species survival standpoint, they say it makes sense. "We have hundreds of species of cicadas, but only nine species that do this periodicity thing," said Sebastián Vélez, entomologist and biology professor at Worcester State University. "It's all natural selection. There is something called 'stragglers.'" Some may emerge after 12 years, some at 14, some after 13 years, and in the case of the current emergence, 17 years. This may increase the odds of more cicadas surviving long enough to reproduce, and even if many get eaten by birds and other predators. Over time, there will simply be too many for hunters to eat so many of them that it jeopardizes the next generation. Another hypothesis, said Vélez, is that a lengthy period of living beneath the earth is a sensible adaptation from a time when glaciers are believed to have covered much of the region. "Neither of these two ideas are fool proof, and no one has been able to test it," said Vélez. In a time when invasive species have caused great damage to our forests, it's natural to have concerns about an insect that depends on trees. "The only harm they do is lay their eggs in the roots of trees. That weakens the tree. When the first molt comes out of the ground, they have a little straw that punctures a plant ... they tap into that, like a little straw. But, they don't harm crops. They won't kill your trees," said Vélez. And, they're not interested in your vegetable garden. "The nymphs of the periodical cicadas feet on tree roots, but there is no evidence that they negatively impact trees," Jennifer Forman Orth, environmental biologist of the state Department of Agricultural Resources. Orth said there is some evidence that in the long run, the cicadas may benefit trees, due to the nutrient cycling, as well as the shell left behind in the process of reaching the adult stage. And, after the cicada dies, it will enrich the soil, Orth said. Simisky agrees. "Actually, it makes the canopy of trees healthier over time. You can cover immature trees with bird nettings, with openings less than half an inch, and that will keep the adult cicadas from laying eggs in those small trees." Simisky said, "Adults laying eggs on mature, established trees, actually act like a pruning for them," Simisky added, "One side effect of having adult periodical cicadas above ground and in folks' yards, is trees like oak, apple, ash, birch, is the females will be laying their eggs in the small branches of these trees. It will cause some leaves to turn dry or brown. That is a natural process." The sound of the cicada is like a theme song of summer: that long, reedy hum on a hot, drowsy day. But how do they do that? They don't have vocal cords. And when the male sings, how does the female hear? Firstly, that sound is mostly associated with the so-called "dog day" cicadas, the ones that emerge every year, perhaps not as spectacular in appearance as their periodic relatives, but still making their presence known. "The cicadas that folks all across Massachusetts might be more familiar with are the annual 'dog day' cicadas," Simisky said. With dark brown, black or green features, and black eyes, "Their timing is a little bit different," with appearances in July or August. The male periodic cicadas tend to cluster in a group, and all try really, super hard to attract females by way of really loud sounds. Simisky said, "I can see how some people might be intimidated. Their singing can be loud. The cicada in eastern Massachusetts is one of the quieter cicadas. But when all the males are singing, they are quite loud." How do they do that, anyway? Simisky said, "They have organs on their bodies, called tymbals, on the first segment of their abdomen." Contracting these membranes produces the sound. If you've ever told someone, "You're as cute as a bug's ear," maybe it's time to say, "cute as a bug's typana." What? They're membranous organs that both males and females have, found on the underside of their abdomens, and which register sound. So, I'm that person at a party who, when the subject of insects come up, says without reserve, "All bugs are insects, but not all insects are bugs." Bug is the informal name of everyone in the order, hemiptera, "half wing," basically, the bug club, to which cicadas have membership. By the way, they are edible, but perhaps that's best for a different party. This is maybe a good time to clear the air, as it were: we humans have a peculiar relationship to insects. Unless it's a butterfly, a ladybug (which is really a beetle), or a cute little cricket, something in our primordial brain wants to know: will these things bite, sting or eat me? And if they're plant eaters, are they going to lay waste to our crops? "We do have a natural insect against insects, spiders and snakes, and that makes sense," said Vélez. Because some insects do bite or sting, or carry pathogens, and some insects can devastate crops, and striking a balance is difficult. Simisky said from time to time, someone on social media postulates that those red eyes surely signify a demon in flight. But if anything, the cicada is a vulnerable creature in many ways. Climate change may bring temperature fluctuations that can confuse creatures, cicadas included. Orth said if a building is constructed over a site where cicada nymphs are lying, they may not be able to make that vertical tunnel to the surface, and instead have travel horizontally until they can find an opening. The cicada asks nothing from us, except to live out its life cycle without interference. "Maybe it's unique to me as an entomologist," said Simisky. "I enjoy seeing this insect. It's truly magical that they are only above ground every 17 years. It gives you a sense of the resilience of life on Planet Earth." Every cicada counts. If you find periodic cicadas in your neck of the woods, so to speak, you can reach out to the Department of Agricultural Resources' Brood XIV Project on iNaturalist. This article originally appeared on Telegram & Gazette: Woo! Science: Why cicadas will not go quietly

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