Cardinals at White Sox Prediction: Odds, expert picks, starting pitchers, trends and stats for June 18
Its Wednesday, June 18 and the Cardinals (38-35) are in Chicago to take on the White Sox (23-50).
Sonny Gray is slated to take the mound for St. Louis against Sean Burke for Chicago.
St. Louis smacked Chicago, 12-2, last night to open the series. Brendan Donovan picked up 4 of St. Louis' 13 hits in the game. Edgar Quero had two hits in the loss for the ChiSox.
Lets dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Game details & how to watch Cardinals at White Sox
Date: Wednesday, June 18, 2025
Time: 7:40PM EST
Site: Rate Field
City: Chicago, IL
Network/Streaming: FDSNMW, CHSN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Cardinals at the White Sox
The latest odds as of Wednesday:
Moneyline: Cardinals (-190), White Sox (+157)
Spread: Cardinals -1.5
Total: 8.0 runs
Probable starting pitchers for Cardinals at White Sox
Pitching matchup for June 18, 2025: Sonny Gray vs. Sean Burke
Cardinals: Sonny Gray (7-2, 3.84 ERA)
Last outing: 6/12 at Milwaukee - 4.1IP, 6ER, 8H, 1BB, 4KsWhite Sox: Sean Burke (3-7, 4.71 ERA)
Last outing: 6/11 at Houston - 3.2IP, 7ER, 8H, 1BB, 4Ks
Cardinals: Sonny Gray (7-2, 3.84 ERA)
Last outing: 6/12 at Milwaukee - 4.1IP, 6ER, 8H, 1BB, 4Ks
White Sox: Sean Burke (3-7, 4.71 ERA)
Last outing: 6/11 at Houston - 3.2IP, 7ER, 8H, 1BB, 4Ks
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of Cardinals at White Sox
The Cardinals have won 4 of their last 5 on the road against AL Central teams
The Over is 19-13-3 in the White Sox's home games this season
The Cardinals have covered in 4 of their last 5 games showing a profit of 1.98 units
Brendan Donovan has at least 1 hit in 7 of his last 8 games (12-33)
Edgar Quero is hitting .359 (14-39) in June
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the Cardinals and the White Sox
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Wednesday's game between the Cardinals and the White Sox:
Moneyline: NBC Sports Bet is recommending a play on the St. Louis Cardinals on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
Jay Croucher (@croucherJD)
Drew Dinsick (@whale_capper)
Vaughn Dalzell (@VmoneySports)
Brad Thomas (@MrBradThomas)
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