
Type 2 diabetes and erectile dysfunction: How one couple revived their intimacy
'Many men feel embarrassed when I meet them, the term 'erectile dysfunction' rarely leave their lips. Instead they come in saying things like, 'it's not like it used to be, doctor' or 'it's not working properly down there'. There's often a feeling that they've somehow let themselves or their partner down,' says Ralph.
'It's my job to explain that ED is extremely common – particularly with age and underlying health conditions like diabetes – and that it's a medical issue, not a personal failing.'
Why this occurs, says Ralph, is because prolonged high blood sugar can damage the small blood vessels and nerves which are essential for an erection. 'This reduces blood flow and sensation in the penis. Men with diabetes are also more likely to have low testosterone, which further lowers sexual desire,' he adds.
Ralph also points out that psychological factors such as anxiety or low mood can worsen the problem. While other diabetes-related health problems, such as heart or kidney disease, may also play a role in reducing sexual desire and contributing to erection problems.
A midlife diagnosis that changed the marriage
Sara and Arion first met in 2008, moved in together within two months and welcomed their first child a year later. But their whirlwind romance stood the test of time, as they married and went on to have five sons together, now aged 16, 14, 12, nine and three.
'After so many years together we both know sex isn't the be-all and end-all, but it's certainly the important glue, and I'd say we connected this way three to four times a week' says Sara, who helps run Arion's restaurant. 'Having friends who haven't had passion that actually lasts, we always felt very fortunate in that area.'
A routine check-up a few years ago showed Arion was pre-diabetic. 'Diabetes is more prevalent in the South East Asian community, and in my line of work I'm constantly surrounded by delicious chapatis, naan, and we cook with ghee – admittedly not ideal for insulin levels,' he says.
According to Ralph, pre-diabetes is a 'warning sign' and prompt action – modifying lifestyle factors such as weight loss – can minimise the risks by getting the sugars controlled.
Determined to reverse the condition naturally, Arion improved his diet, installed a treadmill in the front room, and played football with his sons. But despite these efforts, by 43, he'd tipped into full Type 2 diabetes. This too, alas, is common says professor Ralph. 'Many patients progress to full blown diabetes, and all of the cardiovascular complications including ED.'
That's when things started to change in the bedroom.
'For someone who is naturally full of beans, Arion became more lethargic,' describes Sara. 'His erections were weaker, and intercourse became a struggle.'
The psychological impact of ED on a relationship
Sara admits she worried Arion had stopped finding her attractive. 'After five babies my body had changed, however many kegel exercises I did. There were tense evenings, and the longer it carried on, the more Arion lost his confidence. His enthusiasm for sex waned, I'm sure he feared it would result in failure.' She knew they needed to talk about it – but not during sex.
'I didn't want to bring it up while in bed, with all that pressure. So instead, the two of us we went out for a walk and I said, 'I love you, come on, let's talk about this.' Arion seemed relieved I'd raised it. 'Of course I still fancy you,' he reassured me. And I cried, 'Of course I don't think you're letting me down.' That initial conversation was an important first step.
Together, they focused on non-penetrative ways to stay intimate. 'We tried massages, different positions, using sex toys, and yes – forgive me if this is frank – we practised more oral sex,' admits Sara says. 'It was worth us both improving our technique, and just lightening up a little if things didn't work out.'
What are the treatment options and technical advances for ED?
When Arion decided he wasn't ready to stop having sex in the way they were used to, he went to the GP, who suggested Viagra.
PDE5 inhibitor oral medications – like sildenafil (Viagra) or tadalafil (Cialis) – remain the first-line treatment according to Ralph. These work by temporarily improving blood flow.
'However, they don't address another key issue that many men with ED face – the problem of blood leaking back out too quickly, which can make it hard to maintain an erection. Studies indicate that around half of men stop taking them within a year. Patients often report side effects like headaches or flushing and do not like having to plan sex around a pill.'
Treatments for ED have advanced considerably, says Professor Ralph, with far more available today than 10 years ago. Second-line options include NHS-provided mechanical vacuum devices, which help draw blood back into the penis. 'While these are effective and non-invasive, many men find them inconvenient or uncomfortable long-term,' admits Professor Ralph.
Penile injections are another alternative. 'Alprostadil injections (which relax the blood vessels in the penis) are used when oral treatments fail and are effective in the majority of cases, but drawbacks include pain, priapism risk (an unwanted erection lasting hours), and the need for self-injection,' says Professor Ralph.
Penile implants are available too, but this surgical option tends to be reserved for more complex or persistent cases. They're irreversible but associated with high satisfaction rates.
'More recently, there's been growing interest in treatments that aim to restore function more naturally – especially among men (such as Arion) who want longer-term solutions or don't like the idea of planning sex around a pill.'
One example is low-intensity shockwave therapy which is a private treatment that uses sound waves to stimulate blood flow and encourage new blood vessel growth.
'It can benefit some, particularly those with mild ED, but the clinical results are mixed, and it requires multiple clinic visits, and can cost up to £3000 ($6,800),' explains Professor Ralph.
'Another option is Vertica, a handheld, at-home device, using radiofrequency energy to improve blood flow and reduce venous leak, a common cause of ED,' he adds.
A peer-reviewed study in the International Journal of Impotence Research reported that 85% of users experienced improvement at four weeks, and 93% had erections sufficient for penetration by 12 weeks.
It's approved by the MHRA (Medicines and Healthcare products Regulatory Agency) though is not available on the NHS and costs approximately £1250-£1500 ($2,800 - $3,400) , depending on the model.
Interestingly, says Ralph, the device worked just as well in men with diabetes 'who are typically harder to treat'.
'Around 40% of men in the trial had Type 2 diabetes – given how often ED and diabetes go hand in hand that's encouraging.'
Finding a way forward their sex life – what finally worked
For Arion personally, 'who doesn't even like taking paracetamol' it was the drug-free solution, Vertica, that worked.
'After about a month of using the device three to four times a week consistently we noticed a difference,' says Arion. 'My morning erections returned, full sex was mostly possible, and crucially my confidence improved,' says Arion. 'It felt like turning back time in a way we didn't think possible.'
Today, the couple feel closer than ever. 'It's just like normal again, before his diabetes diagnosis,' Sara says. 'We laugh more, talk more, touch more. We came through this hurdle together, and who knows, we're not ruling out baby number six in the future...'
The diabetes red flags to watch out for
The symptoms for both Type 1 diabetes and Type 2 can be similar, but Type 1 diabetes usually develops more quickly and is more common in younger people. The most common symptoms of Type 2 diabetes are:
Feeling very tired
Peeing more than usual
Feeling thirsty all the time
Losing weight without trying to
Other symptoms can include:
Blurred vision
Cuts or wounds taking longer to heal
Itching around your penis or vagina, or you keep getting thrush
Erectile dysfunction
These symptoms are the same for both adults and children. If you get symptoms (not everyone gets them), they may develop gradually and if concerned speak to your GP.
How to recognise ED
Early signs include reduced firmness, especially during morning erections, and difficulty maintaining an erection during intercourse.

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NZ Herald
6 days ago
- NZ Herald
Type 2 diabetes and erectile dysfunction: How one couple revived their intimacy
'It's one of the most common complications of the disease – yet it's also one of the least discussed,' says consultant urologist professor David Ralph, of University College London. 'Many men feel embarrassed when I meet them, the term 'erectile dysfunction' rarely leave their lips. Instead they come in saying things like, 'it's not like it used to be, doctor' or 'it's not working properly down there'. There's often a feeling that they've somehow let themselves or their partner down,' says Ralph. 'It's my job to explain that ED is extremely common – particularly with age and underlying health conditions like diabetes – and that it's a medical issue, not a personal failing.' Why this occurs, says Ralph, is because prolonged high blood sugar can damage the small blood vessels and nerves which are essential for an erection. 'This reduces blood flow and sensation in the penis. Men with diabetes are also more likely to have low testosterone, which further lowers sexual desire,' he adds. Ralph also points out that psychological factors such as anxiety or low mood can worsen the problem. While other diabetes-related health problems, such as heart or kidney disease, may also play a role in reducing sexual desire and contributing to erection problems. A midlife diagnosis that changed the marriage Sara and Arion first met in 2008, moved in together within two months and welcomed their first child a year later. But their whirlwind romance stood the test of time, as they married and went on to have five sons together, now aged 16, 14, 12, nine and three. 'After so many years together we both know sex isn't the be-all and end-all, but it's certainly the important glue, and I'd say we connected this way three to four times a week' says Sara, who helps run Arion's restaurant. 'Having friends who haven't had passion that actually lasts, we always felt very fortunate in that area.' A routine check-up a few years ago showed Arion was pre-diabetic. 'Diabetes is more prevalent in the South East Asian community, and in my line of work I'm constantly surrounded by delicious chapatis, naan, and we cook with ghee – admittedly not ideal for insulin levels,' he says. According to Ralph, pre-diabetes is a 'warning sign' and prompt action – modifying lifestyle factors such as weight loss – can minimise the risks by getting the sugars controlled. Determined to reverse the condition naturally, Arion improved his diet, installed a treadmill in the front room, and played football with his sons. But despite these efforts, by 43, he'd tipped into full Type 2 diabetes. This too, alas, is common says professor Ralph. 'Many patients progress to full blown diabetes, and all of the cardiovascular complications including ED.' That's when things started to change in the bedroom. 'For someone who is naturally full of beans, Arion became more lethargic,' describes Sara. 'His erections were weaker, and intercourse became a struggle.' The psychological impact of ED on a relationship Sara admits she worried Arion had stopped finding her attractive. 'After five babies my body had changed, however many kegel exercises I did. There were tense evenings, and the longer it carried on, the more Arion lost his confidence. His enthusiasm for sex waned, I'm sure he feared it would result in failure.' She knew they needed to talk about it – but not during sex. 'I didn't want to bring it up while in bed, with all that pressure. So instead, the two of us we went out for a walk and I said, 'I love you, come on, let's talk about this.' Arion seemed relieved I'd raised it. 'Of course I still fancy you,' he reassured me. And I cried, 'Of course I don't think you're letting me down.' That initial conversation was an important first step. Together, they focused on non-penetrative ways to stay intimate. 'We tried massages, different positions, using sex toys, and yes – forgive me if this is frank – we practised more oral sex,' admits Sara says. 'It was worth us both improving our technique, and just lightening up a little if things didn't work out.' What are the treatment options and technical advances for ED? When Arion decided he wasn't ready to stop having sex in the way they were used to, he went to the GP, who suggested Viagra. PDE5 inhibitor oral medications – like sildenafil (Viagra) or tadalafil (Cialis) – remain the first-line treatment according to Ralph. These work by temporarily improving blood flow. 'However, they don't address another key issue that many men with ED face – the problem of blood leaking back out too quickly, which can make it hard to maintain an erection. Studies indicate that around half of men stop taking them within a year. Patients often report side effects like headaches or flushing and do not like having to plan sex around a pill.' Treatments for ED have advanced considerably, says Professor Ralph, with far more available today than 10 years ago. Second-line options include NHS-provided mechanical vacuum devices, which help draw blood back into the penis. 'While these are effective and non-invasive, many men find them inconvenient or uncomfortable long-term,' admits Professor Ralph. Penile injections are another alternative. 'Alprostadil injections (which relax the blood vessels in the penis) are used when oral treatments fail and are effective in the majority of cases, but drawbacks include pain, priapism risk (an unwanted erection lasting hours), and the need for self-injection,' says Professor Ralph. Penile implants are available too, but this surgical option tends to be reserved for more complex or persistent cases. They're irreversible but associated with high satisfaction rates. 'More recently, there's been growing interest in treatments that aim to restore function more naturally – especially among men (such as Arion) who want longer-term solutions or don't like the idea of planning sex around a pill.' One example is low-intensity shockwave therapy which is a private treatment that uses sound waves to stimulate blood flow and encourage new blood vessel growth. 'It can benefit some, particularly those with mild ED, but the clinical results are mixed, and it requires multiple clinic visits, and can cost up to £3000 ($6,800),' explains Professor Ralph. 'Another option is Vertica, a handheld, at-home device, using radiofrequency energy to improve blood flow and reduce venous leak, a common cause of ED,' he adds. A peer-reviewed study in the International Journal of Impotence Research reported that 85% of users experienced improvement at four weeks, and 93% had erections sufficient for penetration by 12 weeks. It's approved by the MHRA (Medicines and Healthcare products Regulatory Agency) though is not available on the NHS and costs approximately £1250-£1500 ($2,800 - $3,400) , depending on the model. Interestingly, says Ralph, the device worked just as well in men with diabetes 'who are typically harder to treat'. 'Around 40% of men in the trial had Type 2 diabetes – given how often ED and diabetes go hand in hand that's encouraging.' Finding a way forward their sex life – what finally worked For Arion personally, 'who doesn't even like taking paracetamol' it was the drug-free solution, Vertica, that worked. 'After about a month of using the device three to four times a week consistently we noticed a difference,' says Arion. 'My morning erections returned, full sex was mostly possible, and crucially my confidence improved,' says Arion. 'It felt like turning back time in a way we didn't think possible.' Today, the couple feel closer than ever. 'It's just like normal again, before his diabetes diagnosis,' Sara says. 'We laugh more, talk more, touch more. We came through this hurdle together, and who knows, we're not ruling out baby number six in the future...' The diabetes red flags to watch out for The symptoms for both Type 1 diabetes and Type 2 can be similar, but Type 1 diabetes usually develops more quickly and is more common in younger people. The most common symptoms of Type 2 diabetes are: Feeling very tired Peeing more than usual Feeling thirsty all the time Losing weight without trying to Other symptoms can include: Blurred vision Cuts or wounds taking longer to heal Itching around your penis or vagina, or you keep getting thrush Erectile dysfunction These symptoms are the same for both adults and children. If you get symptoms (not everyone gets them), they may develop gradually and if concerned speak to your GP. How to recognise ED Early signs include reduced firmness, especially during morning erections, and difficulty maintaining an erection during intercourse.


NZ Herald
03-06-2025
- NZ Herald
Vaping has created a toxic monster: Here's what it does to your body and how to quit
He highlights the rise of vapes with a refillable pod which 'look exactly the same as the disposable [products] and maintain a lot of the features which are appealing to kids, including the different colours, crazy flavours, design and pricing'. He therefore believes the impact on youth vaping will be 'minimal' as many simply turn to the reusable products instead. Before the ban even began, researchers from University College London (UCL) believed disposable vape users were already switching to refillable and rechargeable devices in preparation, instead of giving up. Doctors and scientists are continuing to explore the long-term effects of vaping. 'There is growing evidence that e-cigarettes are harmful to health because some include carcinogens such as formaldehyde, [and] some have higher concentrations of nicotine than the cigarettes they are attempting to replace,' says Dr Cary Adams, the chief executive of the UICC. 'Nicotine is also highly addictive, which makes users more susceptible to dependency, and more likely to smoke throughout their lifetime.' What are the risks? People who vape as well as smoke have a greater risk of: Cardiovascular disease Stroke Chronic lung disease Asthma Oral disease While vaping is still significantly better for your health than smoking, charities are particularly concerned because research is suggesting that a significant proportion of people both smoke and vape. According to the Action on Smoking and Health organisation, 39% of current vapers in the UK also smoke. 'It's estimated that electronic cigarettes are 95% less harmful than conventional cigarettes,' says Dr Silvano Gallus, the head of the Laboratory of Lifestyle Epidemiology at the Mario Negri Institute for Pharmacological Research in Milan. 'But studies are showing that a significant proportion of electronic cigarette users are dual users, and data suggests this leads to a greatly increased risk of disease.' Last year, a major study in the prestigious New England Journal of Medicine called for a reassessment of the widely held assumption that vaping can prevent cigarette-related diseases, largely because of the risk of people becoming addicted to both. The study found that dual users had a greater risk of cardiovascular disease, stroke, chronic lung disease, asthma and oral disease compared with people who just smoked. Gallus and others feel that because of this, there is a need for better strategies for helping people transition away from all forms of nicotine, including vapes. How can you quit? So how can you go about quitting vaping? Last week, the first ever Cochrane review – a systematic examination of randomised controlled trials – was published, looking at the evidence for helping people quit nicotine-containing vapes, which is admittedly rather limited. 'From the data, it seems that it's easier to stop vaping than it is to stop smoking, which is good,' says Sairah Salim-Sartoni, a health psychologist who spent 16 years working clinically in NHS stop smoking services. 'But we still don't have any official guidance. I'd love to be able to give a blueprint for how to help people quit vaping, but we don't have those studies yet.' However, from tapering and distraction to apps and drug treatments, there are a number of strategies which can be used to try and break a potent vaping addiction. 1. Tapering While many smokers use vaping as a way of transitioning away from conventional cigarettes, Salim-Sartoni says that it is possible to become completely nicotine-free. 'A lot of the smokers I know do want to get rid of their dependence on using anything, and it takes time to do that,' she says. 'The number one thing which people can try is to slowly reduce their nicotine strength.' She describes one particular patient who went from smoking to vaping and then eventually nicotine-free, through tapering down in steps, for example from 20mg/ml nicotine to 18mg/ml, 12mg/ml, 9mg/ml, 6mg/ml, 3mg/ml and then to zero. 'That is very feasible, and there's different ways you can do that,' she says. 'You could either vape less often, or go to a nicotine pouch or a nicotine replacement therapy gum, and then slowly reduce your intake.' However, she says that it's important to make sure that as you reduce your nicotine strength, for example through switching to lower strength vapes, you're not vaping more often. 'Unfortunately sometimes when people try and reduce their nicotine strength, they just vape more and more because they're [subconsciously] still trying to get to the level they had before, and they actually end up consuming more nicotine,' she says. 2. Identify your triggers Dr Sharon Levy is a Harvard Medical School associate professor who also heads the addiction medicine division at Boston Children's Hospital. She says the initial symptoms of nicotine withdrawal persist for somewhere between two and four weeks after completely stopping vaping. However the cravings last significantly longer, up to two months for most people, although they tend to fade over time. 'Making it through the first three months after quitting is a major milestone,' says Dr Levy. 'Though unfortunately people are not entirely out of the woods at that point because they are still at risk of being triggered if they are stressed, in a situation that they'd previously associated with nicotine use, or if they see other people using nicotine.' Because of this, Levy recommends meeting with a behavioural therapist to help identify triggers which you can recognise and avoid, as well as working on healthy stress management techniques. 'When someone becomes addicted to a substance, it's as if their brain mistakes the substance use as a behaviour that's critical for survival,' she says. 'So it takes a lot of money and energy for them to prevent themselves from defaulting to using it. Behavioural health counsellors can help people to unlearn this automatic defaulting.' Some vapes contain more nicotine than traditional cigarettes. Photo / 123RF 3. Set boundaries A key component of behavioural management is not only identifying your triggers but setting boundaries. 'They're very similar tactics you would use for stopping smoking that you can apply to vaping as well,' says Salim-Sartoni. 'You can set rules for where you do and do not vape, so basically saying I'm only using my vape when I'm outside, but the home and car, I do not vape. Lower the nicotine, extend the time between vaping and set rules for where you do and don't vape.' Because this isn't always easy, Salim-Sartoni says that finding 'a buddy' who is also attempting to quit vaping can provide a vital support network which can make the whole process of setting boundaries much easier. 4. Distraction Finding a way to distract the brain is a key aspect of breaking any substance addiction. Salim-Sartoni says that there are all kinds of methods you can use to disengage your brain from the nicotine cravings, such as going to drink water, going to the toilet, playing a game on your phone or going for a walk. One surprisingly effective means of distraction is having a boiled sweet. 'The glucose receptor is very close to the nicotine receptor,' says Salim-Sartoni. 'And so the nicotine receptor feels that it's had something. The science steadily emerged to show this, but in our stop smoking clinics, we realised early on that people were eating a lot of sweet stuff when they were trying to quit, and this is why.' 5. Try apps or text message interventions According to the recent Cochrane review, some trials have found that text message-based interventions, which provide regular support and advice on quitting vaping can be effective. One study which examined a text message-based quit-vaping programme showed that users who used the programme were 35% more likely to quit vaping nicotine within seven months. As well as text message services, Levy says that there are a number of freely available apps and chatbots such as This is Quitting, which provide regular tips and encouragement, which have been shown to be effective in increasing quit rates. 6. Drug therapies For more powerful nicotine addictions, there are also pharmacological therapies such as the prescription drugs varenicline and cytisine. Varenicline binds to the nicotine receptors in the brain and blocks them, preventing the nicotine in vapes from binding to them, and so reducing withdrawal symptoms and cravings. Cytisine mimics the effects of nicotine and so tricks the brain into thinking it has ingested nicotine, which also reduces cravings. Finally, Salim-Sartoni emphasises that the most important thing of all for people looking to quit vaping, particularly ex-smokers, is that they don't return to smoking cigarettes again. 'Smoking is uniquely deadly, and some people can't stop nicotine or don't want to,' she says. 'If that's the case, then it is much better that they switch to e-cigarettes, particularly with the Government's ambition to reduce smoking rates in the UK to 5% or less by 2030.'


Scoop
22-04-2025
- Scoop
We Cannot Turn A Blind Eye To Preventable Epidemics If We Are To Deliver On SDGs
The epidemic-proportion diseases and untimely deaths caused by tobacco use are entirely preventable. Likewise, we have science-based tools and approaches to find all TB cases, treat all of them and prevent transmission of the disease. When even one TB or tobacco death is a death too many, how can one explain 1.25 million TB deaths and over 8 million tobacco-related deaths in 2023 alone? How can TB disease, that is entirely preventable (and curable), become the deadliest infectious disease worldwide? Ahead of World No Tobacco Day 2025 as well as the World Conference on Tobacco Control 2025, Dr Tara Singh Bam, a noted and dedicated leader who has championed both #endTB and #endTobacco agenda – along with connecting more dots, like prevention and control of non-communicable diseases (NCDs), and invoking stronger local actions at sub-national levels to advance progress towards these goals- shared valuable insights on "TB and tobacco: A preventable tragedy, a shared responsibility." Dr Bam called for building result oriented political leadership that translates into effective TB and tobacco control legislation; accountability and sustainability of TB control and tobacco control programmes; and inclusion of smoking cessation through regular TB services at healthcare facilities. Dr Bam serves as Asia Pacific Director for Tobacco Control at Vital Strategies and earlier led the International Union Against Tuberculosis and Lung Disease (The Union) Asia Pacific as its Director. He also serves as a Board Director of Asia Pacific Cities Alliance for Health and Development (APCAT). TB and tobacco both deadly by themselves and together become deadlier TB if left untreated can be deadly. And as per the World Health Organization (WHO), one out of every two tobacco user dies of tobacco-related diseases prematurely. There is ZERO safe level of tobacco use, so tobacco use in all forms is deadly and dangerous for health as well as for the economy. Health is a fundamental human right. So, ending tobacco use and ending TB are urgent priorities for not only global health but also for sustainable development. In addition, both tobacco use and TB jolt our economies. Tobacco causes a loss of US$ 1.4 trillion to the global economy every year. Hence investing in TB and tobacco control is a smart and necessary investment if governments want to deliver on SDGs. For example, every US$ 1invested in TB control yields a return of US$ 46. Agrees Dr Vineet Bhatia, Regional Advisor for TB at the World Health Organization (WHO) in the Southeast Asian region: 'If we must end TB, we must address its determinants – tobacco smoking is an important determinant of TB. WHO Southeast Asian region is the highest TB burden region globally accounting for nearly 5 million new TB patients and around 600,000 deaths in 2023.' Tobacco (industry) fuels TB TB is caused by bacteria but what about tobacco products? Every tobacco-related disease and death could have been averted. But the tobacco industry goes on deceiving us to fill up its bank coffers. Let us hope governments hold them to account and put people before profits. 'TB and tobacco both are big public health threats. Link between TB and tobacco smoking is strong. And well documented scientifically. Tobacco makes it harder to diagnose and treat TB, leads to more severe illness and raises the chances of TB recurrence and even TB death. According to the WHO if we eliminate tobacco use then we can reduce TB rates by up to 20%,' said Dr Gan Quan, who has made a distinguished contribution to tobacco and TB control at The Union earlier, and now serves at Vital Strategies. Dr Vineet Bhatia agrees: 'There is an increased risk of contracting TB as tobacco use impairs the immune system, making it easier for the TB bacteria to infect the lungs. Tobacco smoke impairs the immune response, including ciliary dysfunction, which impairs the clearance of TB bacteria from the respiratory tract. Tobacco smokers have a higher risk of recurrent TB. Smoking negatively influences the response to TB treatment and increases the likelihood of relapse. Smoking is also associated with more severe forms of TB, including cavitary disease and increases the risk of death from TB. Moreover, exposure to second-hand smoke (and third-hand smoke) also increases TB risk, especially in children.' Dr Tara Singh Bam too emphasised: "Passive smoking (second-hand smoking) can increase the risk of TB too, especially the risk of TB infection and progression from latent TB infection to active TB disease as passive smoking impairs lung function and the immune response." Dr Elizabeth Cadena, the new President of The Union Asia Pacific said that 'Tobacco smoking is a major risk factor for lung diseases including TB. There is also association between tobacco smoking and drug-resistant TB. Rates of tobacco use prevalence are declining in all WHO regions, but slowest decline is in the Western Pacific region where high TB burden countries are also located.' The world is not on track to end TB or end tobacco: Why? While remarkable progress has been made in the fight against TB, mountainous challenges still remain towards #endTB: 'More than 3.8 million people were put on TB treatment in 2023 in WHO Southeast Asian region - the highest ever reported in any single year. At the same time, the number of people who were being missed by the TB programmes in this region halved between 2020-2023 (from 44% in 2020 to 22% in 2023). TB deaths reduced too. 'From 763,000 TB deaths in 2021 in WHO Southeast Asian region, the number came downwards to 583,000 in 2023,' said Dr Bhatia. Undernutrition is the biggest TB risk factor globally Undernutrition is not only the biggest TB risk factor worldwide but also in WHO Southeast Asian region. As per the WHO Global TB Report 2024, globally, out of the estimated 10.8 million new TB cases in 2023 (however, only 8.2 million were reported by TB programmes worldwide, rest were missed), almost one million of them were attributed to undernutrition, 752,000 TB cases were attributed to alcohol, 702,000 TB cases were attributed to tobacco use, 681,000 TB cases were attributed to HIV, and 381,000 TB cases were attributed to diabetes. In WHO Southeast Asian region, out of the estimated 4.9 million TB cases in 2023 (of which only 3.8 million cases were notified), over half a million (552,000) TB cases were attributed to undernutrition, followed by 328,000 attributed to tobacco use, 311,000 attributed to alcohol use, 173,000 attributed to diabetes and 92,000 attributed to HIV. Tobacco is the biggest TB risk factor in Indonesia Although undernutrition is overall the biggest TB risk factor globally as well as in southeast Asian region, but for Indonesia, tobacco smoking is the biggest risk factor (followed by undernutrition, diabetes, HIV and alcohol use), said Dr Bhatia. Agrees Dr Gan Quan: 'In Indonesia, one in three TB cases- over 300,000 people - get TB due to tobacco use. According to a few studies, up to 96% of male TB patients in the country smoke tobacco. It is a powerful reminder of how closely these two epidemics are intertwined. If we are serious about ending TB then we have to end tobacco use – that means, higher tobacco taxes, ending all forms of tobacco marketing, standardised health warnings on all tobacco packaging, making indoor spaces smoke- free, and offering support to tobacco users to quit.' In addition, tobacco industry is the biggest threat to implementation of evidence-based tobacco control measures, as well as to the global tobacco treaty (formally called the WHO Framework Convention on Tobacco Control or WHO FCTC), that calls upon governments to stop tobacco industry interference in public policy (Article 5.3) and hold tobacco industry legally and financially liable for the harms they have knowingly caused to human race and our planet (Article 19). Antimicrobial Resistance and tobacco use Dr Vineet Bhatia shared that in 2024 he was part of WHO Indonesia Drug-Resistant TB Mission along with Dr Conradie Francesca of WHO HQ. They found that there were a significant number of patients who were started on individualised drug-resistant TB treatment regimens (but not on the WHO recommended shorter DR-TB treatment regimens) because of extensive lung lesions. The biggest probable causes for this were: late diagnosis, smoking (as a lot of these patients were smokers), undernutrition and other co-morbidities associated with TB. #EndTB and #EndTobacco as enablers of progress towards SDGs Strong science-based evidence shows how we can screen everyone (regardless of TB symptoms) in high burden settings and offer them upfront molecular testing to find ALL TB, link them to same-day-test-and-treat with best of TB regimens (after doing drug susceptibility testing), and implement the full cascade of TB prevention (like TB preventive therapy, ending malnutrition, ending tobacco and alcohol use, diabetes prevention and control, ensuring every person living with HIV has made undetectable equals untransmittable a reality, and addressing other TB risk factors). But reality on how we find TB, treat TB or prevent TB is far away from this science-based approach. Let us bridge this gap. Likewise, it is high time that governments fully implement science-based tobacco control measures (such as MPOWER measures recommended by WHO and WHO FCTC) and end tobacco use. Dr Gan Quan said that in countries like India, Indonesia, Bangladesh and Pakistan, integrating tobacco smoking cessation programmes into routine TB services has led to more people quitting tobacco smoking. Dr Tiffany Tiara Pakasi, Head of Indonesian government's national TB programme, also stresses upon strengthening integration between TB programme as well as tobacco control programme to benefit the people even more. Dr Bhatia of WHO calls for urgent need for targeted interventions to address the two co-epidemics of TB and tobacco use. With only 67 months left to deliver on the promise of SDGs, it is high time accelerated action becomes a reality to end TB and end tobacco, along with enabling progress towards achieving all other SDGs. Shobha Shukla, Bobby Ramakant – CNS (Citizen News Service)