Padres at Diamondbacks Prediction: Odds, expert picks, starting pitchers, betting trends, stats for August 4
San Diego is one of the hottest teams in the league with seven wins in the last eight games and held eight of the last nine opponents to three or fewer runs scored.
Arizona has won two straight games after losing the past six and are 5-9 over the last 14 contests San Diego is 4-3 against Arizona this season with one series win and one 2-2 split.
Let's dive into the matchup and find a sweat or two. We've got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.
Game details & how to watch Padres at Diamondbacks
Date: Monday, August 4, 2025
Time: 9:40PM EST
Site: Chase Field
City: Phoenix, AZ
Network/Streaming: SDPA, ARID, MLBN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Padres at the Diamondbacks
The latest odds as of Monday:
Moneyline: Padres (-142), Diamondbacks (+120)
Spread: Padres -1.5
Total: 9.0 runs
Probable starting pitchers for Padres at Diamondbacks
Pitching matchup for August 4, 2025: JP Sears vs. Brandon Pfaadt
Padres: JP Sears, (7-9, 4.95 ERA)Last outing: 4.15 ERA, 2 Earned Runs Allowed, 5 Hits Allowed, 3 Walks, and 6 Strikeouts
Diamondbacks: Brandon Pfaadt, (10-7, 5.11 ERA)Last outing: 13.50 ERA, 7 Earned Runs Allowed, 11 Hits Allowed, 0 Walks, and 3 Strikeouts
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Expert picks & predictions for tonight's game between the Padres and the Diamondbacks
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Monday's game between the Padres and the Diamondbacks:
Moneyline: NBC Sports Bet is recommending a play on the San Diego Padres on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Arizona Diamondbacks at +1.5.
Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 9.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.
Top betting trends & insights to know ahead of Padres at Diamondbacks
San Diego is 7-1 in the last eight games
Arizona is 2-6 in the last eight games
The Padres' record in their last 5 games stands at 4-1
The Over is 14-11-1 in the Padres' matchups against NL West teams this season
The Padres have covered in 4 of their last 5 games showing a profit of 3.53 units
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Follow our experts on socials to keep up with all the latest content from the staff:
Jay Croucher (@croucherJD)
Drew Dinsick (@whale_capper)
Vaughn Dalzell (@VmoneySports)
Trysta Krick (@Trysta_Krick)
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