Padres at Nationals Prediction: Odds, expert picks, starting pitchers, betting trends and stats for July 18
Dylan Cease is slated to take the mound for San Diego against Michael Soroka for Washington.
The Padres sit in second place and 5.5 games behind the Dodgers in the National League West. They won six of their last ten prior to the All-Star Break. Mired again this season in last place in the National League East, Washington overhauled their front office and coaching staff prior to the Break. Pitching has been the primary issue as the Nats have allowed 519 runs. Only the Rockies (589) and the Athletics (551) have allowed more.
Lets dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Padres at Nationals
Date: Friday, July 18, 2025
Time: 6:45PM EST
Site: Nationals Park
City: Washington, DC
Network/Streaming: SDPA, MASN
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Padres at the Nationals
The latest odds as of Friday:
Moneyline: Padres (-157), Nationals (+132)
Spread: Padres -1.5
Total: 8.0 runs
Probable starting pitchers for Padres at Nationals
Pitching matchup for July 18, 2025: Dylan Cease vs. Michael Soroka
Padres: Dylan Cease (3-9, 4.88 ERA)Last outing: July 9 vs. Arizona - 6IP, 6ER, 5H, 3BB, 8Ks
Nationals: Michael Soroka (3-7, 5.35 ERA)Last outing: July 10 at St. Louis - 4IP, 2ER, 4H, 2BB, 4Ks
Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!
Top betting trends & insights to know ahead of Padres at Nationals
The Padres have won 7 of their last 9 games at Washington
The Over is 5-0 in the Nationals' last 5 home games
The Padres have covered in 4 of their last 5 games showing a profit of 1.93 units
Fernando Tatis Jr. is enjoying a 6-game hitting streak (9-21)
Manny Machado was 3-10 (.300) in the Padres' 3-game series against the Phillies just prior to the Break
James Wood is 10-41 (.244) with 2 HRs and 5 RBIs in July
If you're looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the Padres and the Nationals
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Friday's game between the Padres and the Nationals:
Moneyline: NBC Sports Bet is recommending a play on the San Diego Padres on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Washington Nationals at +1.5.
Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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