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Can this popular sugar substitute fight pancreatic cancer? Here's what new study says

Can this popular sugar substitute fight pancreatic cancer? Here's what new study says

Hindustan Times6 days ago
A popular sugar substitute found in many kitchens may one day contribute to cancer treatment. A new study from Hiroshima University in Japan has revealed that stevia leaf extract, when fermented with specific bacteria, could help fight pancreatic cancer cells. Research on fermented stevia extract offers hope for pancreatic cancer treatment. (Freepik)
Stevia, derived from the plant Stevia rebaudiana, is widely used as a natural sweetener. However, the study published in the International Journal of Molecular Sciences on 26 March 2025 focused on what happens when the extract is fermented.
Can stevia help fight pancreatic cancer
Researchers found that this version of the extract showed strong antioxidant properties and cytotoxic effects against pancreatic cancer cells in lab tests. These findings suggest that fermented stevia extract could be a promising future candidate for cancer therapy.
"This study is interesting because it shows that something naturally derived, like stevia, can be modified to potentially stop cancer cells from growing in the lab," said Dr. Paul E. Oberstein, a medical oncologist and assistant director at NYU Langone's Pancreatic Cancer Centre, in an interview with Fox News Digital.
Stevia is a natural sweetener.(Shutterstock)
However, he clarified that the regular stevia plant itself doesn't impact cancer cells. The fermentation process is key to enhancing its potential, and there's still a lot to learn about how the modified extract might behave in real-world scenarios. "This wasn't tested on humans, so we don't yet know whether it's safe or effective for patients," Oberstein cautioned. "It's exciting from a research perspective, but not something that will change cancer treatment protocols right away."
Is it safe for patients?
Dr. Kristen Arnold, a surgical oncologist and pancreatic cancer expert at the Orlando Health Cancer Institute, also weighed in. She emphasised how challenging pancreatic cancer is to treat and noted that any encouraging early data is a welcome development.
"Pancreatic cancer is incredibly aggressive, and despite our most intensive treatments, outcomes are often poor," she said. "We're constantly exploring better treatment options, and this kind of research gives us hope."
While the findings are preliminary, Arnold called the study "exciting" and part of the ongoing process of discovery in cancer research. "This is how we eventually find breakthrough treatments, some ideas may not work out, but others can lead to dramatic improvements in patients' lives."
Both doctors emphasised the importance of continued research and clinical trials. For those diagnosed with pancreatic cancer, Arnold recommended discussing trial opportunities with their medical teams, as these studies often guide the future of treatment.
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Hormonal causes of hair loss in women and how to manage them
Hormonal causes of hair loss in women and how to manage them

Time of India

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Hormonal causes of hair loss in women and how to manage them

Hormonal imbalances are a common cause of hair loss in women. Key hormones like androgens (including DHT), estrogen, progesterone, cortisol, thyroid hormones, and insulin all influence the hair growth cycle. When these hormones are too high or too low, they can disrupt the normal growth and shedding of hair, causing thinning and hair loss. Factors such as menopause, stress, thyroid issues, PCOS, diabetes, genetics, and certain medications often trigger these imbalances. Understanding how hormones affect hair and addressing the underlying causes can help manage hair loss and promote healthier, fuller hair. How hormones affect your hair growth Many people try quick fixes and believe common myths about hair loss without understanding the real causes. In reality, hair naturally grows in cycles: a growth phase (anagen), a transition phase (catagen), and a resting or shedding phase (telogen). According to research published in the International Journal of Molecular Sciences, hormones play a key role in controlling how long each phase lasts and how healthy the hair follicles remain. When hormone levels, such as DHT, estrogen, or cortisol, are out of balance, they can disrupt these cycles, leading to thinning hair and increased shedding. Knowing the truth about hormonal effects helps in managing and treating hair loss effectively. Dihydrotestosterone (DHT): This androgen hormone, a derivative of testosterone, is known for its role in male characteristics but is also present in women at lower levels. According to a study published in the National Institutes of Health, excessive DHT can shrink scalp hair follicles, shorten the growth phase, and lengthen the shedding phase. This leads to thinning hair, especially at the crown and along the part line, a condition called female pattern hair loss or androgenic alopecia. Estrogen: Estrogen supports the anagen phase, helping hair stay in the growth cycle longer, which promotes thicker and longer hair. It also blocks testosterone from converting into DHT within hair follicles. When estrogen levels drop, such as during menopause, hair follicles prematurely enter the resting phase, leading to hair thinning and increased shedding. Progesterone: This hormone regulates menstrual cycles and supports pregnancy. Like estrogen, progesterone helps inhibit the conversion of testosterone into DHT. Low progesterone can indirectly raise DHT levels in the scalp, contributing to hair loss. Cortisol: Known as the stress hormone, cortisol spikes during emotional or physical stress, triggering a form of temporary hair loss called telogen effluvium. High cortisol levels push hair follicles into an extended resting phase, causing noticeable hair shedding and thinning a few months after a stressful event. Thyroid Hormones: The thyroid gland produces hormones vital for metabolism and overall bodily function, including hair follicle health. Both hypothyroidism (low thyroid hormone) and hyperthyroidism (high thyroid hormone) disrupt the hair growth cycle, causing hair to become brittle, thin, and prone to shedding. Insulin: Insulin regulates blood sugar by facilitating glucose uptake into cells. Insulin resistance or deficiency leads to elevated blood sugar levels, damaging blood vessels and reducing oxygen and nutrient supply to hair follicles. This impairment can slow hair growth and promote hair thinning. Insulin imbalances may also increase DHT production, further exacerbating female pattern hair loss. What causes hormonal imbalance and hair loss? Several health and lifestyle factors contribute to hormone-related hair loss in women: Menopause: During menopause, estrogen and progesterone levels decline sharply. This hormonal shift shortens the hair growth phase and permits more testosterone to convert into DHT, increasing the risk of female pattern hair loss. Stress: Physical or emotional stress elevates cortisol, which can cause telogen effluvium, a temporary but often significant hair shedding occurring several months after the stressor. Thyroid Disease: Both overactive and underactive thyroid conditions disrupt hormone balance, leading to hair thinning. Thyroid medication may help restore hair growth, though some drugs can initially worsen hair loss. Polycystic Ovary Syndrome (PCOS): PCOS raises androgen levels, including DHT, leading to hair loss primarily on the front scalp and temples. Medical treatment of PCOS often improves hair regrowth. Diabetes: Poor insulin regulation in diabetes can reduce nutrient flow to hair follicles, causing thinning and hair loss. Genetics and Aging: A family history of female pattern baldness increases susceptibility to DHT-driven hair loss. Aging naturally shifts hormone levels, potentially worsening hair thinning. Hormonal Birth Control: Some birth control pills with higher androgenic activity may worsen hair loss in women already sensitive to DHT. Managing hormonal hair loss: key lifestyle tips for healthier hair and hormone balance While hormonal hair loss is not always preventable, certain lifestyle and medical strategies can help manage symptoms and promote healthier hair: Reduce Stress: Incorporate stress-relieving activities such as meditation, yoga, hobbies, or spending time outdoors to lower cortisol levels. Maintain a Balanced Diet: Eating nutrient-rich foods supports hormone production and overall health. Exercise Regularly: Physical activity helps regulate hormones like insulin and reduces stress. Prioritize Sleep: Aim for 7-8 hours of sleep nightly to support hormone balance and recovery. Some women may need medical help to balance hormones and reduce hair loss. If you notice sudden or severe hair loss, bald patches, or other unusual symptoms, it's important to consult your healthcare provider promptly. Early diagnosis can help identify any underlying hormonal issues and guide you toward the right care. Understanding that hormonal imbalances often cause hair loss is the first step in addressing the problem effectively and maintaining healthier hair over time. Seeking professional advice ensures you get the appropriate support for your individual needs. Also Read: Don't eat these 5 foods if you want to stop nasal polyps from getting worse

How To Make Apple Cider Vinegar Moringa For Belly Fat, Gut Health And Skin Glow
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How To Make Apple Cider Vinegar Moringa For Belly Fat, Gut Health And Skin Glow

The world of wellness is constantly evolving, and every few months, a new superfood or supplement takes centre stage. While the market is flooded with trendy ingredients to try, many ancient remedies are quietly but steadily finding their way back into our routines. From turmeric lattes to ashwagandha gummies, the revival of time-tested traditions is hard to ignore. One such drink currently gaining traction across social media and health circles is Apple Cider Vinegar (ACV) Moringa. Touted for benefits ranging from weight loss and improved digestion to clearer skin and better immunity, it is appearing in everything from fizzy tablets to bottled tonics. But before reaching for a packaged version, here is a simple homemade recipe that is not only more affordable but also allows you to control what goes into your drink. If you are looking to start your mornings with something nourishing, earthy, and gently energising, this is one to try. 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The drink is: Easy to prepare at home More affordable than packaged alternatives Believed to support digestion, detox, skin health and weight management Apple Cider Vinegar (ACV) has been studied for its wide-ranging benefits. A review in the British Journal of Medical and Health Sciences highlighted ACV's anti-obesity, anti-diabetic, antimicrobial and antioxidant properties. It may help regulate lipid levels and improve liver metabolism. Moringa oleifera, often called the "miracle tree," is equally well-researched. A study published in the International Journal of Molecular Sciences confirmed its anti-inflammatory and antioxidant effects, with bioactive compounds such as flavonoids and alkaloids contributing to its therapeutic value. Together, ACV and moringa may support nutrient absorption, metabolic function and gentle detoxification. Photo Credit: Pexels How To Make ACV Moringa At Home? Ingredients: 1 tsp raw, unfiltered apple cider vinegar Half tsp organic moringa powder 1 cup warm water Optional: pinch of cinnamon or lemon juice for flavour Method: Mix ACV and moringa powder into warm water Stir well and let it sit for 2-3 minutes Drink on an empty stomach or 30 minutes before meals Expert tip: The drink has an earthy, tangy flavour that may be off-putting. If sugar is not a concern, a small amount of honey or jaggery may improve the taste. What Does ACV Moringa Taste Like? ACV Moringa has a strong, earthy taste with a sour kick. Moringa adds a slightly grassy note, while ACV is sharp and acidic. Together, the flavour may be unusual, especially if you are trying it for the first time. To balance the taste: Add a dash of honey or jaggery if sugar is not a concern Squeeze in lemon juice or a pinch of cinnamon for a brighter flavour Use a straw to avoid direct contact with teeth and to reduce aftertaste The taste might take some getting used to, but many find it easier to drink after a few tries. Can I Make ACV Moringa In Advance? It is best to prepare ACV Moringa fresh every morning to preserve the nutrients and taste. Apple cider vinegar and moringa both contain active compounds that can degrade or become bitter when left to sit for too long. However, if mornings are rushed, you can: Pre-mix the moringa powder and store it dry in a small jar Keep ACV in a measuring bottle for quick pouring Warm the water and mix just before drinking Avoid making the full drink in advance and storing it overnight, as the texture and taste may become unpleasant. Can Moringa Help With Belly Fat? While there is no magic fix for belly fat, moringa may support overall fat loss. It contains compounds that help break down fat and reduce inflammation. A study in the Journal of Food Science and Technology found that moringa leaves had cholesterol-lowering effects, which may contribute to weight loss. Combined with ACV, thought to suppress appetite and improve insulin sensitivity, this drink may support weight management when paired with balanced meals and regular physical activity. Which Type Of Apple Cider Vinegar Works Best For Weight Loss? Always opt for raw, unfiltered apple cider vinegar with the "mother"-a cloudy substance that contains beneficial enzymes and bacteria. Flavoured or sweetened versions should be avoided, as they may include added sugars. Type of ACV: Type Pros Cons Raw and unfiltered May support weight loss, digestion May irritate sensitive stomach Pasteurised Milder taste Lower nutritional potency Flavoured Tastes better Often contains added sugar Can Moringa Support Liver Detox? Yes, moringa has traditionally been used for liver support. According to experts, it may help prevent non-alcoholic fatty liver disease by reducing fat accumulation in the liver. Its antioxidant and anti-inflammatory properties are thought to aid natural liver detox functions. What Should Not Be Mixed With Apple Cider Vinegar? Despite its benefits, there are certain combinations to avoid with ACV, especially when consumed regularly. 1. Milk or Dairy Products: Mixing ACV with milk causes curdling, as its acidity denatures the proteins in milk. While this is harmless when cooking, drinking it may lead to bloating or discomfort. Wait at least 30-45 minutes between consuming ACV and dairy. 2. High-Dose Medications: If you are taking insulin or diuretics, consult a doctor. ACV may interfere with potassium levels and affect blood sugar control. 3. Undiluted ACV: Drinking ACV straight is not advisable. It may erode tooth enamel, irritate the throat or oesophagus, and cause reflux or nausea. Always dilute 1-2 teaspoons in a full glass of water. Also, wait at least 30 minutes after consumption before brushing your teeth to avoid enamel erosion. When Should You Drink ACV Moringa For Weight Loss? Mornings are generally preferred, as the drink may support metabolism and help control cravings. Paired with moringa, it may leave the body feeling lighter and more energised. However, some individuals prefer taking it at night-at least one hour before bed. Consult a healthcare expert to identify a timing and dosage that aligns with your health status. Who Should Avoid ACV Moringa? Although ACV Moringa is popular among wellness enthusiasts, it is not suitable for everyone. Those with the following conditions should speak with a doctor before adding it to their routine: Pregnant or breastfeeding women: Moringa may trigger uterine contractions due to its alkaloid content. The acidity of ACV may also cause heartburn or digestive discomfort during pregnancy. People with kidney or liver conditions: Moringa may lower blood pressure or affect kidney function, particularly when consumed regularly. Individuals on medication: ACV may interact with insulin, diuretics, or heart medications. It can also affect potassium levels. People with sensitive stomachs or acid reflux: The acidity of ACV can worsen acid reflux and may irritate the digestive tract. If you experience discomfort, it is best to pause consumption and consult a medical expert. How Long Does It Take For ACV Moringa To Show Results? There is no fixed timeline, as results depend on individual metabolism, diet and lifestyle. Some people may notice reduced bloating or improved digestion within a week, while others might take a few weeks to see changes in skin clarity or weight management. Consistency matters more than quantity. Drinking ACV Moringa regularly, paired with balanced meals and regular physical activity, tends to yield better results over time. Possible Side Effects Of Drinking ACV Moringa Daily: While the ACV Moringa drink is associated with several wellness benefits, overuse or improper use can lead to side effects: 1. Tooth Enamel Damage: Undiluted ACV is highly acidic and can wear down enamel, causing tooth sensitivity and decay. 2. Stomach Upset: ACV may cause acidity, bloating or nausea in some individuals. Moringa, in large amounts, can act as a laxative. 3. Uterine Contractions: Pregnant or breastfeeding women should seek medical advice. Moringa contains alkaloids that may cause uterine contractions, and ACV may aggravate digestive issues. 4. Kidney Impact: Moringa may affect kidney function and blood pressure. Those with hypotension or kidney issues should avoid daily intake. 5. Allergic Reactions: Although rare, allergic responses can occur, ranging from rashes to breathing difficulties. Always begin with small doses. How To Reduce Risks While Drinking ACV Moringa? Always dilute 1-2 teaspoons of ACV in water Start with small quantities of moringa powder Avoid combining ACV with milk or dairy Do not drink it immediately after meals or just before sleeping Wait at least 30 minutes before brushing your teeth Consult a healthcare provider if you have underlying health conditions Final Thoughts: Is ACV Moringa Worth Including In Your Routine? If you are seeking a natural way to support digestion, skin health and metabolism, ACV Moringa may be a worthy addition. The homemade version is budget-conscious and easy to tailor. Just remember, it is not a miracle solution-its benefits are best experienced when it complements a balanced lifestyle.

Can this popular sugar substitute fight pancreatic cancer? Here's what new study says
Can this popular sugar substitute fight pancreatic cancer? Here's what new study says

Hindustan Times

time6 days ago

  • Hindustan Times

Can this popular sugar substitute fight pancreatic cancer? Here's what new study says

A popular sugar substitute found in many kitchens may one day contribute to cancer treatment. A new study from Hiroshima University in Japan has revealed that stevia leaf extract, when fermented with specific bacteria, could help fight pancreatic cancer cells. Research on fermented stevia extract offers hope for pancreatic cancer treatment. (Freepik) Stevia, derived from the plant Stevia rebaudiana, is widely used as a natural sweetener. However, the study published in the International Journal of Molecular Sciences on 26 March 2025 focused on what happens when the extract is fermented. Can stevia help fight pancreatic cancer Researchers found that this version of the extract showed strong antioxidant properties and cytotoxic effects against pancreatic cancer cells in lab tests. These findings suggest that fermented stevia extract could be a promising future candidate for cancer therapy. "This study is interesting because it shows that something naturally derived, like stevia, can be modified to potentially stop cancer cells from growing in the lab," said Dr. Paul E. Oberstein, a medical oncologist and assistant director at NYU Langone's Pancreatic Cancer Centre, in an interview with Fox News Digital. Stevia is a natural sweetener.(Shutterstock) However, he clarified that the regular stevia plant itself doesn't impact cancer cells. The fermentation process is key to enhancing its potential, and there's still a lot to learn about how the modified extract might behave in real-world scenarios. "This wasn't tested on humans, so we don't yet know whether it's safe or effective for patients," Oberstein cautioned. "It's exciting from a research perspective, but not something that will change cancer treatment protocols right away." Is it safe for patients? Dr. Kristen Arnold, a surgical oncologist and pancreatic cancer expert at the Orlando Health Cancer Institute, also weighed in. She emphasised how challenging pancreatic cancer is to treat and noted that any encouraging early data is a welcome development. "Pancreatic cancer is incredibly aggressive, and despite our most intensive treatments, outcomes are often poor," she said. "We're constantly exploring better treatment options, and this kind of research gives us hope." While the findings are preliminary, Arnold called the study "exciting" and part of the ongoing process of discovery in cancer research. "This is how we eventually find breakthrough treatments, some ideas may not work out, but others can lead to dramatic improvements in patients' lives." Both doctors emphasised the importance of continued research and clinical trials. For those diagnosed with pancreatic cancer, Arnold recommended discussing trial opportunities with their medical teams, as these studies often guide the future of treatment.

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