Repare Therapeutics Jumps 15% After $10M Licensing Deal With Debiopharm
Warning! GuruFocus has detected 5 Warning Signs with RPTX.
Under the deal, Repare will receive $10 million upfront and could earn up to $257 million in milestone payments, including $5 million in near-term payouts. The company is also entitled to single-digit royalties on future global sales of lunresertib.
Debiopharm will now take over the MYTHIC study and lead all development efforts for the drug, which had previously been tested in combination with Debiopharm's own WEE1 inhibitor, Debio 0123.
This deal ensures lunresertib continues development without draining internal resources, said Repare CEO Steve Forte, who also serves as president and CFO. Forte added that the drug has shown "encouraging results" in early trials.
Following the deal, Repare plans to concentrate on two internal programs:
RP-1664, a PLK4 inhibitor under study in the LIONS trial
RP-3467, a Pol? ATPase inhibitor being tested in the POLAR trial
The company expects data readouts from both studies in H2 2025.
Debiopharm CEO Bertrand Ducrey called the combination of lunresertib and Debio 0123 highly synergistic and potentially capable of producing rapid and deep tumor regressions.
This article first appeared on GuruFocus.
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