Can Statins Reverse Fatty Liver Disease?
There is no evidence to show that statins can reverse fatty liver disease, also known as metabolic dysfunction-associated steatotic liver disease (MASLD). However, they may be able to help prevent the progression of the condition.
Statins are medications typically used to lower cholesterol and reduce the risk of heart disease.
A 2025 review found that, as statins have anti-inflammatory properties, they may be able to prevent the progression of MASLD by:
reducing fat around the liver
decreasing inflammation
improving scarring and damage of the liver
improving liver function
It's important to remember that statins are not the standard treatment option for MASLD and should not be used in place of a prescribed treatment.
How can fatty liver be reversed?
Fatty liver can be reversed if it is in its early stages before any liver damage has occurred.
There are several ways to reduce fatty liver during this period, such as:
Lifestyle measures. Making lifestyle adjustments during the initial stages of MASLD is vital to slowing down the progression of the condition and potentially reversing the condition. This includes:
following a healthy diet
getting regular exercise
avoiding or limiting alcohol consumption
losing weight if you have overweight or obesity
Treating underlying conditions. Several conditions, such as diabetes and high cholesterol, can lead to fat accumulating around the liver. Addressing these underlying conditions may help to manage symptoms and potentially reverse MASLD.
Early diagnosis.
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