RIPK1 Inhibitor Pipeline 2025: Latest FDA Approvals, Clinical Trials, and Emerging Therapies Assessment by DelveInsight

Globe and Mail

05-08-2025

RIPK1 Inhibitor pipeline constitutes 10+ key companies continuously working towards developing 12+ RIPK1 Inhibitor treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.
' RIPK1 Inhibitor Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the RIPK1 Inhibitor Market.
The RIPK1 Inhibitor Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the RIPK1 Inhibitor Pipeline Report:
Companies across the globe are diligently working toward developing novel RIPK1 Inhibitor treatment therapies with a considerable amount of success over the years. RIPK1 Inhibitor Key players such as - Sanofi, Genfleet Therapeutics, Rigel Pharmaceuticals, GlaxoSmithKline, AbbVie, Sanofi, Voronoi, Boston Pharmaceuticals, Sironax, Nuevolution, and others, are developing therapies for the RIPK1 Inhibitor treatment
RIPK1 Inhibitor Emerging therapies such as - SAR443122, GFH312, R552, and others are expected to have a significant impact on the RIPK1 Inhibitor market in the coming years.
In May 2025, Accropeutics' investigational drug has successfully met the primary objectives in a Phase 2 clinical trial for psoriasis conducted in China, leading the company to commit to accelerating the clinical advancement of its TYK2/JAK1 inhibitor, AC-201. In the trial, 145 Chinese patients with moderate to severe plaque psoriasis were administered one of three doses of AC-201 or a placebo. All dosing groups achieved the primary endpoint, with a significantly higher proportion of patients reaching a 75% improvement in their Psoriasis Area and Severity Score (PASI 75) at Week 12 compared to the placebo group.
In October 2024, Sanofi discontinued its Phase 2 clinical trial of oditrasertib, an experimental RIPK1 inhibitor, in patients with relapsing and progressive multiple sclerosis (MS) after the treatment did not achieve its primary objectives. Initiated early last year, the trial failed to demonstrate a significant reduction in neurofilament light chain (NfL) levels — a biomarker associated with neurodegeneration. Additionally, the therapy did not meet any major secondary endpoints, as noted in a recent SEC filing by Denali Therapeutics, Sanofi's development partner.
RIPK1 Inhibitor Overview
A RIPK1 inhibitor is a type of drug that blocks the activity of Receptor-Interacting Serine/Threonine-Protein Kinase 1 (RIPK1) — an enzyme involved in regulating inflammation, cell death (especially necroptosis), and immune responses. Overactivation of RIPK1 has been linked to several diseases, including autoimmune disorders, neurodegenerative conditions, and inflammatory diseases. By inhibiting RIPK1, these drugs aim to reduce excessive inflammation and tissue damage, offering a promising therapeutic strategy for conditions like multiple sclerosis, Alzheimer's disease, and psoriasis.
Emerging RIPK1 Inhibitor Drugs Under Different Phases of Clinical Development Include:
RIPK1 Inhibitor Pipeline Therapeutics Assessment
RIPK1 Inhibitor Assessment by Product Type
RIPK1 Inhibitor By Stage and Product Type
RIPK1 Inhibitor Assessment by Route of Administration
RIPK1 Inhibitor By Stage and Route of Administration
RIPK1 Inhibitor Assessment by Molecule Type
RIPK1 Inhibitor by Stage and Molecule Type
DelveInsight's RIPK1 Inhibitor Report covers around 12+ products under different phases of clinical development like
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Download Sample PDF Report to know more about RIPK1 Inhibitor drugs and therapies
RIPK1 Inhibitor Pipeline Analysis:
The RIPK1 Inhibitor pipeline report provides insights into
The report provides detailed insights about companies that are developing therapies for the RIPK1 Inhibitor treatment with aggregate therapies developed by each company for the same.
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for RIPK1 Inhibitor Treatment.
RIPK1 Inhibitor key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
RIPK1 Inhibitor Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the RIPK1 Inhibitor market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Scope of RIPK1 Inhibitor Pipeline Drug Insight
Table of Contents
1
RIPK1 Inhibitor Report Introduction
2
RIPK1 Inhibitor Executive Summary
3
RIPK1 Inhibitor Overview
4
RIPK1 Inhibitor- Analytical Perspective In-depth Commercial Assessment
5
RIPK1 Inhibitor Pipeline Therapeutics
6
RIPK1 Inhibitor Late Stage Products (Phase II/III)
7
RIPK1 Inhibitor Mid Stage Products (Phase II)
8
RIPK1 Inhibitor Early Stage Products (Phase I)
9
RIPK1 Inhibitor Preclinical Stage Products
10
RIPK1 Inhibitor Therapeutics Assessment
11
RIPK1 Inhibitor Inactive Products
12
Company-University Collaborations (Licensing/Partnering) Analysis
13
RIPK1 Inhibitor Key Companies
14
RIPK1 Inhibitor Key Products
15
RIPK1 Inhibitor Unmet Needs
16
RIPK1 Inhibitor Market Drivers and Barriers
17
RIPK1 Inhibitor Future Perspectives and Conclusion
18
RIPK1 Inhibitor Analyst Views
19
Appendix
20
About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
Media Contact
Company Name: DelveInsight
Contact Person: Gaurav Bora
Email: Send Email
Phone: [phone]
Address: 304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/