Latest news with #JamesRowe
Yahoo
6 days ago
- Sport
- Yahoo
'I'm so proud' - Linnets boss Rowe after opening day show
King's Lynn Town 1 AFC Telford Utd 1 'It was always going to be eventful, wasn't it, if I was the manager? It always is.' And so, in just 17 words, James Rowe summed up what it will be like for King's Lynn Town fans this season. The head coach was more like a ringmaster in his dugout - animated, cajoling, urging his team on, berating them when it went wrong. When his opposite number Kevin Wilkin bemoaned a referee's decision, Rowe was ready to pounce with his opinion. Officials get rarely a moment's rest, and Rowe even urged the crowd to get on their backs as well – not that it takes a lot of doing. It was high energy stuff – on and off the pitch. And, when the 90-minute storm had final abated, Rowe was calmness personified, happy to give his thoughts but keen to get to his family and some different post-match banter. Lynn started with just three players from last season - Gold Omotayo, Ross Crane and Tom Wilson – with new owner Joseph Phua sitting in the stands, after a whirlwind 16-hour trip from Singapore, the return leg of which began immediately after the game. It was all very 'new' – and if what transpired on the pitch is repeated, Lynn fans will surely love this rollercoaster ride. Yes, Lynn should have won and on another day might have had the game tucked up before half-time. But a new squad, considerably younger than last season's, will live and learn. 'I'm so proud, because we're a young group and the enthusiasm and the attacking intent that we played was outstanding,' he said. 'To have 24 shots at home, you expect to score more than one goal. And I think we got 34 box entries as well, so those stats back up the pride, really. 'And 1-0 at home against us at half-time, as a young group could have gone the other way, but they've showed great character. They've come out even stronger and we played better in the second half. I thought for 30 minutes before their goal, we were very, very good. And again, that shows a young group that, after their goal, they had the best spell of their game. So we need to make sure we react better when adversity comes, that'll come as we learn along the journey. 'But my overriding feeling is pride.' It took a Michael Gyasi equaliser just before the hour mark to earn a point, after Matt Stenson had put the visitors ahead on 35 minutes from the penalty spot. Lynn had enjoyed the bulk of the play for much of the opening period, before the visitors came into the game. Gyasi had the balI in the net on four minutes but was ruled offside, but the returnee then slipped in Crane who, with the keeper advancing, fired over from close range. All the opening forays were in the visitors' half, and debutant Joe Nyahwema almost made the most of it on 17 minutes when he cut in from the left and fired a rocket of a shot against the bar from 25 yards. Louis Chadwick, preferred in goal to the experienced Paul Jones, denied Stenson a second, but whatever Rowe said to his players at the break worked. Bar the odd foray from the visitors, it was all Lynn. The reward came when Crane found Gyasi with a drilled ball down the middle and the striker switched on the after-burners before slotting the ball past keeper Alfie Brooks. Gyasi twice went close to scoring a winner, but make no mistake, this is a very different player to the one that struggled at times during his first spell at The Walks. His upper body strength, his confidence, his speed – all improved. In the final reckoning, despite some close shaves and some excellent defending by the visitors, Lynn had to settle for a point. But the thumbs up verdict from the crowd was unanimous. They rather like this bright new world. King's Lynn Town: Chadwick, Hall-Johnson (Williams 89(, Clements, Wilson, Fleming, Clunan, Nyahwema, M Williams, Crane (Forde-Brown 69), Gyasi (Collins 81), Omotayo. Subs: Jones, Doherty, Dickens, Marriott. Goal: Gyasi 59 AFC Telford Utd: Brooks, Harper, Cranston, Pendley, Williams (George 77), Rowe, Stenson (Ilesammi 77), Cawthorne, Hilton (Lawal 57), Leshabela, Walker (Armson 86). Subs not used: Fletcher, Allen-Hadley, Cook, Armson. Goal: Stenson 35 pen Att: 1,354
Yahoo
04-07-2025
- Sport
- Yahoo
Linnets prepare for opening test of the summer
Step one of the James Rowe era goes public on Saturday afternoon with King's Lynn Town's first cobweb-brushing game of the summer. The Linnets make the short trip to Fakenham Town (3pm), with all eyes on how Rowe will line up his team and how different the dynamic will be from the side that ended last season with disappointment in the National League North play-offs. Advertisement That defeat at Chorley triggered a collapse of two regimes – manager Adam Lakeland's, after he laid bare some facts about budgetary cuts, and owner Stephen Cleeve's, as Turn Sports Investments (TSI) took charge. Rowe stepped into the head coach role and set about managing a budget and reinvigorating the squad, with the word 'community' echoing around The Walks. That's another new era, with Cleeve's one-man band now departed and the liaison with a supporters' trust front and centre of promoting brand King's Lynn Town. Around 400 season ticket sales, so far, is early proof of the fans' vote of confidence in the new-look club. But it is what happens on the pitch that will ultimately determine whether this summer of upheaval has worked. Advertisement Rowe has been around the game too long to get sucked into long-term predictions, but the turnover of players, in and out, has been sufficient to stir up plenty of optimism. Rowe has signed 12 players, including former Linnets Tai Fleming, Adam Marriott, Michael Gyasi and new skipper Michael Clunan. There are high hopes for Lynn boy Fletcher Toll, who will be looking to take a prolific scoring record to its highest level yet, as well as Sam Collins, Bailey Clements , Joe Nyahwema and Archie Crowther, while Rowe has done well to persuade Reece Hall-Johnson and Jack Lambert to move to The Walks. Goalkeeper Louis Chadwick will challenge Paul Jones for the shirt in another intriguing duel. They all join current players Jones, Ross Crane, Theo Williams, Tom Wilson, Matty Warburton, Kyle McFadden and Cameron Forde-Brown. Inevitably, some quality players have left - Dylan Crowe (FC Halifax), Jonny Margetts (Gainsborough), Josh McCammon (Spalding), Tommy Hughes, Greg Taylor (Bedford Town), Josh Coulson (Newmarket Town), Sam Walker (FC Halifax), Bailey Marsden (Marine), Finlay Barnes (Ebbsfleet United)), Kian Ronan (Chelmsford City), Freddie Sass (Accrington Stanley), Josh Hmami, Finley Whiteley (Newmarket Town), Paulius Falcao and keeper Patrick Boyes. Advertisement That churn is the consequence of upheaval, but the goalposts have been deliberately shifted with a noticeable swing to a younger squad average age. Getting the balance right is key. 'The remit's quite clear,' Rowe told official club channels. 'The directive from the ownership model in terms of what we want to do here and what sort of club we want to be. Dropping the age is no slight on what's happened before me. 'I'm one to look at the present and looking forward in terms of the remit, it's quite a clear directive in the direction we want to go - we want to be a club where we nurture young talent, whether that's coming from players that have done well at step three, step four and coming up, or whether that's players such as Sam Collins coming down who have not had the opportunities perhaps at a Cat 1 club, who are looking for that first step in professional football and that platform to play 46 games. 'Hopefully we can build on those signings this summer going forward into the season and into next and my time here and we can really have a solid base of talent coming through. Advertisement 'But alongside that it's important that if you chuck 11 youngsters together you tend to struggle so it's important that you have a good mix and with Paul Jones, Kyle McFadden, Mike Clunan, Adam Marriott etc we've got a spine there of experience, Matt Warburton as well, so in terms of that experience around the younger group on and off the field it's crucial. So always striking a balance is important with the squad.'
The Sun
18-06-2025
- Entertainment
- The Sun
Dancing On Ice star Vanessa Bauer stuns in sizzling swimsuit snaps from Bali getaway with boyfriend
DANCING On Ice star Vanessa Bauer has stunned in a series of sizzling swimsuit snaps from her Bali getaway with her boyfriend. It was back in December when the skating pro revealed new boyfriend James Rowe, after a romantic trip to Lapland. 6 6 6 Both she and James, 33, took to Instagram to share loved-up posts from their winter wonderland holiday. Footballer James previously played for Reading FC and went on to play for Cheltenham town, followed by Aldershot Town. Now, the brunette beauty and her man have jetted off again, this time to Bali. Vanessa shared some stunning photos sat on the shore at night. She penned: 'liquid or frozen, happiest by the water 🌊🧊 (once I've eaten) 'thanks to a kind stranger @momohead_ for taking the covert last picture from a far, this was such a beautiful moment ♥️' The brunette beauty put on a sensational display in the series of photos, in a glistening orange bikini. Vanessa let her hair down in beachy waves and sported a makeup free look, while standing up for some of the photos. In another snap, she could be seen with her boyfriend James, as they posed in swimwear while enjoying an al-fresco feast. Dancing on Ice star quits series just hours before live show after devastating injury 'How absolutely beautiful,' one fan wrote, while another said: 'I aspire to be as happy as you whether it's on the ice or off you're just radiating it.' The star's romance with James comes after she split from boyfriend of nine months Dan Underwood in June of last year. And Vanessa previously hinted she could quit Dancing On Ice as she pursues an acting career. She told The Sun: "My acting pursuit is going really well. "I'm actually working on a movie right now as well, so I'm super excited for this to come out next year. "I love Dancing On Ice and I would love to continue doing it for as long as I can but at the same time, other opportunities are piling up and I'm super grateful for everything coming my way right now." The show was recently shelved by ITV with no plans for a new series. It comes after ratings dwindled for this year's series, which was won by Corrie's Sam Aston. 6 6
Daily Mail
18-06-2025
- Entertainment
- Daily Mail
Vanessa Bauer sizzles in a skimpy metallic bikini during moonlit swim as she jets off on romantic trip to Bali with her new boyfriend James Rowe
Vanessa Bauer sizzled in a skimpy metallic bikini as she shared an album of loved-up holiday snaps from her romantic trip to Bali with her new boyfriend James Rowe. The professional figure skater, 28, took to Instagram on Tuesday to share a series of eye-popping snaps of herself showing off her incredible figure in the racy two-piece. She let her beachwear outfit do all the talking as she kept her accessories minimal while striking a series of sultry poses during her moonlit dip in the sea. Vanessa also shared a sweet picture of her cuddling up to her new boyfriend James while they enjoyed a meal together. The couple were later seen watching the sun rise as they sat next to one another on the beach. Alongside the post, she penned: 'liquid or frozen, happiest by the water (once I've eaten) thanks to a kind stranger @momohead_ for taking the covert last picture from a far, this was such a beautiful moment.' Vanessa went public with her James in December as she shared a series of loved-up Instagram snaps from their trip to Lapland. James is a football coach and FIFA-licensed football agent. He retired from professional football after playing for Reading FC, Cheltenham Town and Aldershot Town. Alongside the sweet carousel of snaps, Vanessa took the opportunity to reflect on her father's death in 2021, claiming she has now got to a place in her life where she feels 'the happiest I've ever been.' 'A pull between feeling the happiest I've ever been but the moment I fly home for Christmas a different reality kicks in,' she added. 'I believe that the pulls between my upbringing, our families' loss and the beautiful life I get to live now is not a burden but in a way it can be seen as a blessing. 'And I certainly am grateful for my family and the 25 years I got to know my dad.' She continued: 'Perspective has created the person I am now, to keep me grounded, driven, to know life in its many different ways and remain resilient.' 'Gratitude is an understatement and I'll retain the discipline to keep growing my luck.' 'Anything is possible and love and magic truly is everywhere (love heart emoji).' In June last year, Vanessa split from her boyfriend Dan Underwood after just nine months together after sources claimed they had drifted apart. While Vanessa wanted to focus on her career, she and Dan remained friends, and the pair continued to still follow each other on social media. A source told The Sun at the time: 'Vanessa and Dan are still on good terms and are friends, but their job takes them to different parts of the world and they have struggled with the distance.' 'They realised they better off as friends for now, but still have a lot of love and respect for each other. 'Vanessa is busy with her career and is focusing on herself and her acting right now. While Dan is busy travelling the world for work, so it's been difficult to maintain something long-term.' She and Dan previously made their romance official in September 2023, when they posed for snaps together at the premiere of The Creator.
The Guardian
13-06-2025
- Health
- The Guardian
‘Transformative': the UK lab working on a way to halt genetic type of dementia
Behind the gleaming glass facade of an office block in east London's docklands, Dr Martina Esposito Soccoio is pipetting ribonucleic acid into test tubes. Here, not far from Canary Wharf's multinational banks, a British university spinout is working on a breakthrough treatment for a form of dementia suffered by millions of people worldwide. There is no cure for dementia at present, but scientists at AviadoBio hope their clinical studies can stop the progression of a particular genetic type of frontotemporal dementia (FTD). 'It may be one of the first dementias to have a definitive treatment, a cure if you like, a really transformative treatment that allows people to live much longer and much more normal lives,' says Prof James Rowe, consultant neurologist at Cambridge's Addenbrooke's Hospital. FTD mainly affects the front and sides of the brain and unlike Alzheimer's disease, does not begin with memory loss, which tends to occur later. It is characterised by progressive loss of language and changes in personality and behaviour. Most cases are diagnosed in people aged 45 to 65, but it can affect people in their 20s and 30s. There are an estimated 20,000 to 40,000 people living with FTD in the UK, and between 1m and 2m in the world. Rowe says: 'It's a double-edged sword: the young onset, the high genetic burden and rapid illness are also features that perhaps make it more tractable to treat.' The Die Hard and Pulp Fiction actor Bruce Willis, who recently celebrated his 70th birthday, was diagnosed with FTD two years ago, with his family calling it a 'cruel disease'. They have not said whether he has a genetic form of FTD. The gene therapy developed by AviadoBio, which was spun out of Prof Christopher Shaw's research lab at King's College London in 2021, targets a type of FTD known as FTD-GRN. This is caused by mutations of a gene that lead to a deficiency of progranulin (GRN), a protein that is essential for maintaining healthy brain cells. AviadoBio, which employs 60 people, signed an exclusive licence agreement with the Japanese pharma firm Astellas last October to develop the therapy. It is now recruiting patients for its clinical trial in the UK, as well as the US, Poland, Spain, Sweden and the Netherlands. The first patient received the infusion in Warsaw in March 2024, out of six patients who have had the treatment so far, in Poland and the US. All patients will be followed for up to five years as part of the trial. AviadoBio expects to publish the first data next year. Three years ago, Jessica Crawford, from Beverley in Yorkshire, lost her mother to FTD, caused by mutations of another gene, C9orf72. In 2014, when her mother was 58, her behaviour changed; the family suspected depression. Previously very sociable, she stopped going out and started playing games like Candy Crush or watching TV shows 'over and over,' her daughter recounts. Her mother initially did not want to see a doctor, and was only diagnosed with FTD in February 2019. By this time she was so confused she once put raw chicken in a sandwich. 'Getting the diagnosis wasn't easy because FTD wasn't well known; my mum was aceing in the memory tests,' Crawford says. But her mother became increasingly confused and lost the ability to speak, and to communicate at all. Crawford became her full-time carer in 2020, until her mother deteriorated so much that she had to go to a care home in late 2021, and died the following year. Crawford, 33, found out that she herself carries the gene mutation, and with her husband decided to conceive through IVF with a pre-implantation genetic diagnosis. When their five embryos were screened, four had the gene mutation, and the fifth resulted in the birth of their son. The couple donated their other four embryos to science and she takes part in GENFI – a long-running UK-led global study of families with FTD across 40 sites. AviadoBio itself was born out of the research done at King's by Shaw, a neurologist who has focused on FTD and amyotrophic lateral sclerosis (ALS) for more than three decades, and Dr Youn Bok Lee and Dr Do Young Lee from the UK Dementia Research Institute's centre based at King's. ALS, the most common form of motor neurone disease, has also been linked to mutations of the GRN gene and leads to muscle weakness, paralysis and eventually death. Sign up to Business Today Get set for the working day – we'll point you to all the business news and analysis you need every morning after newsletter promotion Shaw acts as the company's chief scientific and clinical adviser, and while the Lees are no longer involved in the firm's research, all three remain shareholders. David Cooper, AviadoBio's chief medical officer, says: 'It was something that hit me when I first joined the company, you look at the MRI scans of patients with a GRN mutation, the frontal and temporal parts of their brain are just melting away … So we really need earlier treatment, an, earlier diagnosis and a more organised healthcare approach to deal with it.' AviadoBio's lead product, known as AVB-101, is infused directly into the brain by a neurosurgeon using a cannula as thin as a strand of angel hair pasta, during a 90-minute procedure guided by MRI. It delivers a functional copy of the progranulin gene to restore appropriate levels of the protein to affected areas of the brain. It is a once-only treatment, and no immunosuppressant drugs are needed subsequently. 'The patients who have FTD are born with almost half of the progranulin levels that you and I might have,' says chief executive Lisa Deschamps. 'Our goal in the study is to supplement the GRN gene and restore as much progranulin in these individuals as possible to normal levels to reduce the neurodegeneration effect. Other medications in development at AviadoBio include two gene therapies, from Philadelphia-based Passage Bio and Eli Lilly-owned Prevail Therapeutics, but they do not target the thalamus, the 'relay station' in the brain. Passage Bio's therapies are delivered directly to the cerebrospinal fluid in a single treatment. Denmark's Vesper Bio has developed an oral capsule, designed to act on the GRN gene, that is being trialled at University College London Hospital. AviadoBio, whose investors include Johnson & Johnson's innovation arm and the UK not-for-profit LifeArc Ventures, is part of a growing life science cluster in Canary Wharf. At its labs, scientists – assisted by robotics – research how to target a particular gene. 'The UK has real strengths in this area,' says Rowe, pointing to the international GENFI study, run since 2011 by Prof Jonathan Rohrer, a neurologist from UCL Queen Square Institute of Neurology who also sits on AviadoBio's scientific advisory board. 'It's a real win for the UK.'
