
Brandon Aiyuk injury update: 49ers WR expected back about Week 6
The Arizona Cardinals will likely not have to face one of the better wide receivers in the NFC West in one of their two games with the San Francisco 49ers. Their first matchup with the San Francisco 49ers, on the road in Week 3, 49ers receiver Brandon Aiyuk is not expected to play.
They do have somewhat of a timeline, though. Head coach Kyle Shanahan estimated that Aiyuk could return in Week 6.
He is currently on the PUP list as he recovers from the serious knee injury he suffered in Week 7 last season, tearing both his ACL and MCL.
That means the 49ers' top two receivers in Week 3 will be Jauan Jennings and second-year receiver Ricky Pearsall. The, of course, still have running back Christian McCaffrey and tight end George Kittle, but their passing attack will not be as potent without the dynamic threat that Aiyuk is.
In 2023, his last healthy season, he had 75 receptions for 1,342 yards and seven touchdowns.
In his last game against the Cardinals in Week 5 of 2024, he had eight receptions for 147 yards.
Get more Cardinals and NFL coverage from Cards Wire's Jess Root and others by listening to the latest on the Rise Up, See Red podcast. Subscribe on Spotify, YouTube or Apple podcasts.

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